1A4I

HUMAN TETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE

Summary for 1A4I

DescriptorMETHYLENETETRAHYDROFOLATE DEHYDROGENASE / METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywordsthf, bifunctional, dehydrogenase, cyclohydrolase, folate, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P11586
Total number of polymer chains2
Total molecular weight66791.93
Authors
Allaire, M.,Li, Y.,Mackenzie, R.E.,Cygler, M. (deposition date: 1998-01-30, release date: 1999-02-09, Last modification date: 2011-07-13)
Primary citation
Allaire, M.,Li, Y.,MacKenzie, R.E.,Cygler, M.
The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution.
Structure, 6:173-182, 1998
PubMed: 9519408 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(98)00019-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.226402.1%5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1a4i
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