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7KLC
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BU of 7klc by Molmil
Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 gp120 core and to 17b Fab
分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kumar, S, Wilson, I.A.
登録日2020-10-29
公開日2021-07-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
3TV3
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BU of 3tv3 by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with Man9
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMYLAMINE, GLYCEROL, ...
著者Pejchal, R, Wilson, I.A.
登録日2011-09-19
公開日2011-10-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
7T2P
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BU of 7t2p by Molmil
The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2021-12-06
公開日2022-10-19
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun, 13, 2022
7T4G
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BU of 7t4g by Molmil
The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2021-12-09
公開日2022-10-19
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun, 13, 2022
8EQN
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BU of 8eqn by Molmil
BG505 UFO-E2p-L4P nanoparticle reconstructed by focused refinement with a mask around the nanoparticle core
分子名称: BG505 UFO-E2p-L4P
著者Antanasijevic, A, Zhang, Y.N, Zhu, J, Ward, A.B.
登録日2022-10-08
公開日2023-04-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimmers as HIV-1 vaccine candidates.
Nat Commun, 14, 2023
7TI6
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BU of 7ti6 by Molmil
Crystal structure of the wild-type least mutated common ancestor (LMCA) of the HIV-targeting PCT64 antibody lineage
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PCT64_LMCA Fab heavy chain, PCT64_LMCA light chain (wild type)
著者Omorodion, O, Wilson, I.A.
登録日2022-01-12
公開日2022-10-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
7T75
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BU of 7t75 by Molmil
HIV-1 Envelope ApexGT2 in complex with RM20A3 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT2 gp120, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2021-12-14
公開日2022-09-28
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
7T74
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BU of 7t74 by Molmil
HIV-1 Envelope ApexGT2 in complex with PCT64.35S Fab and RM20A3 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT2 gp120, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2021-12-14
公開日2022-09-28
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
7T76
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BU of 7t76 by Molmil
HIV-1 Envelope ApexGT3 in complex with PG9.iGL Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT3 gp120, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2021-12-14
公開日2022-09-28
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.43 Å)
主引用文献Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
7T77
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BU of 7t77 by Molmil
HIV-1 Envelope ApexGT3.N130 in complex with PG9 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT3.N130 gp120, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2021-12-14
公開日2022-09-28
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.75 Å)
主引用文献Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
7T73
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BU of 7t73 by Molmil
HIV-1 Envelope ApexGT2.2MUT in complex with PCT64.LMCA Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT2.2MUT gp120, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2021-12-14
公開日2022-09-28
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
3TYG
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BU of 3tyg by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with a glycosylated engineered gp120 outer domain with miniV3 (eODmV3)
分子名称: Envelope glycoprotein gp160, PGT128 heavy chain, Ig gamma-1 chain C region, ...
著者Pejchal, R, Huang, P.S, Schief, W.R, Stanfield, R.L, Wilson, I.A.
登録日2011-09-25
公開日2011-10-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3TWC
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BU of 3twc by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT127 in complex with Man9
分子名称: AMYLAMINE, PGT127 heavy chain, Ig gamma-1 chain C region, ...
著者Pejchal, R, Wilson, I.A.
登録日2011-09-21
公開日2011-10-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
6OLP
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BU of 6olp by Molmil
Full length HIV-1 Env AMC011 in complex with PGT151 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rantalainen, K, Cottrell, C.A.
登録日2019-04-16
公開日2019-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
Plos Pathog., 15, 2019
6OZC
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BU of 6ozc by Molmil
BG505 SOSIP.664 with 2G12 Fab2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 Fab Heavy chain, ...
著者Cottrell, C.A, Ward, A.B.
登録日2019-05-15
公開日2020-05-20
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.79 Å)
主引用文献Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions.
Structure, 28, 2020
6NIJ
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BU of 6nij by Molmil
PGT145 Fab in complex with full length AMC011 HIV-1 Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 Glycoprotein 120, ...
著者Cottrell, C.A, Torrents de la Pena, A, Rantalainen, K, Torres, J.L, Ward, A.B.
登録日2018-12-29
公開日2019-07-31
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
Plos Pathog., 15, 2019
7T6X
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BU of 7t6x by Molmil
Cryo-EM structure of full-length hepatitis C virus E1E2 glycoprotein in complex with AR4A, AT12009, and IGH505 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AR4A Fab, ...
著者Torrents de la Pena, A, Ward, A.B, Eshun-Wilson, L, Lander, G.C.
登録日2021-12-14
公開日2022-11-02
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.83 Å)
主引用文献Structure of the hepatitis C virus E1E2 glycoprotein complex.
Science, 378, 2022
8EJE
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BU of 8eje by Molmil
Structure of lineage II Lassa virus glycoprotein complex (strain NIG08-A41)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein GP1, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJF
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BU of 8ejf by Molmil
Structure of lineage V Lassa virus glycoprotein complex (strain Soromba-R)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJJ
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BU of 8ejj by Molmil
Lassa virus glycoprotein complex (Josiah) bound to S370.7 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJH
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BU of 8ejh by Molmil
Lassa virus glycoprotein complex (Josiah) bound to 12.1F Fab
分子名称: 12.1F Fab heavy chain, 12.1F Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJI
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BU of 8eji by Molmil
Lassa virus glycoprotein complex (Josiah) bound to 19.7E Fab
分子名称: 19.7E Fab heavy chain, 19.7E Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJD
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BU of 8ejd by Molmil
Structure of lineage IV Lassa virus glycoprotein complex (strain Josiah)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJG
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BU of 8ejg by Molmil
Structure of lineage VII Lassa virus glycoprotein complex (strain Togo/2016/7082)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein GP1, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8GJE
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BU of 8gje by Molmil
HIV-1 Env subtype C CZA97.12 SOSIP.664 in complex with 3BNC117 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 Fab heavy chain, ...
著者Ozorowski, G, Lee, J.H, Ward, A.B.
登録日2023-03-15
公開日2023-10-18
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.
Plos Pathog., 19, 2023

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件を2024-11-06に公開中

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