7T73

HIV-1 Envelope ApexGT2.2MUT in complex with PCT64.LMCA Fab

This is a non-PDB format compatible entry.

Summary for 7T73

• Entry DOI: 10.2210/pdb7t73/pdb
• EMDB information: 25732 25733 25734 25735 25736
• Descriptor: PCT64.LMCA Fab Heavy Chain, PCT64.LMCA Fab Light Chain, HIV Envelope ApexGT2.2MUT gp120, ... (9 entities in total)
• Functional Keywords: hiv, germline targeting vaccine, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 288271.06

Authors

Berndsen, Z.T.,Ward, A.B. (deposition date: 2021-12-14, release date: 2022-09-28, Last modification date: 2023-07-05)

• Primary citation: Willis, J.R.,Berndsen, Z.T.,Ma, K.M.,Steichen, J.M.,Schiffner, T.,Landais, E.,Liguori, A.,Kalyuzhniy, O.,Allen, J.D.,Baboo, S.,Omorodion, O.,Diedrich, J.K.,Hu, X.,Georgeson, E.,Phelps, N.,Eskandarzadeh, S.,Groschel, B.,Kubitz, M.,Adachi, Y.,Mullin, T.M.,Alavi, N.B.,Falcone, S.,Himansu, S.,Carfi, A.,Wilson, I.A.,Yates 3rd, J.R.,Paulson, J.C.,Crispin, M.,Ward, A.B.,Schief, W.R.; Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.; Immunity, 55:2149-, 2022; PubMed: 36179689; DOI: 10.1016/j.immuni.2022.09.001

Experimental method

ELECTRON MICROSCOPY (4 Å)