7T74

HIV-1 Envelope ApexGT2 in complex with PCT64.35S Fab and RM20A3 Fab

This is a non-PDB format compatible entry.

Summary for 7T74

• Entry DOI: 10.2210/pdb7t74/pdb
• EMDB information: 25732 25733 25734 25735 25736
• Descriptor: HIV Envelope ApexGT2 gp120, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: hiv, germline targeting vaccine, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1 (HIV-1); More
• Total number of polymer chains: 14
• Total formula weight: 351135.93

Authors

Berndsen, Z.T.,Ward, A.B. (deposition date: 2021-12-14, release date: 2022-09-28, Last modification date: 2023-07-05)

• Primary citation: Willis, J.R.,Berndsen, Z.T.,Ma, K.M.,Steichen, J.M.,Schiffner, T.,Landais, E.,Liguori, A.,Kalyuzhniy, O.,Allen, J.D.,Baboo, S.,Omorodion, O.,Diedrich, J.K.,Hu, X.,Georgeson, E.,Phelps, N.,Eskandarzadeh, S.,Groschel, B.,Kubitz, M.,Adachi, Y.,Mullin, T.M.,Alavi, N.B.,Falcone, S.,Himansu, S.,Carfi, A.,Wilson, I.A.,Yates 3rd, J.R.,Paulson, J.C.,Crispin, M.,Ward, A.B.,Schief, W.R.; Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.; Immunity, 55:2149-, 2022; PubMed: 36179689; DOI: 10.1016/j.immuni.2022.09.001

Experimental method

ELECTRON MICROSCOPY (3.35 Å)