3JB6
 
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ... | | 著者 | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | 登録日 | 2015-08-02 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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3JB7
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | 分子名称: | CPV RNA-dependent RNA polymerase, CYTIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | 登録日 | 2015-08-03 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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3J9D
 | | Atomic structure of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry | | 分子名称: | Outer capsid protein VP2, ZINC ION | | 著者 | Zhang, X, Patel, A, Celma, C, Roy, P, Zhou, Z.H. | | 登録日 | 2015-01-09 | | 公開日 | 2015-12-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Atomic model of a nonenveloped virus reveals pH sensors for a coordinated process of cell entry.
Nat.Struct.Mol.Biol., 23, 2016
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5ZMD
 | | Crystal structure of FTO in complex with m6dA modified ssDNA | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase FTO, DNA (5'-D(P*TP*CP*TP*(6MA)P*TP*AP*TP*CP*G)-3'), MANGANESE (II) ION, ... | | 著者 | Zhang, X, Wei, L.H, Luo, J, Xiao, Y, Liu, J, Zhang, W, Zhang, L, Jia, G.F. | | 登録日 | 2018-04-02 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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3J9E
 | | Atomic structure of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry | | 分子名称: | VP5 | | 著者 | Zhang, X, Patel, A, Celma, C, Roy, P, Zhou, Z.H. | | 登録日 | 2015-01-10 | | 公開日 | 2015-12-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Atomic model of a nonenveloped virus reveals pH sensors for a coordinated process of cell entry.
Nat.Struct.Mol.Biol., 23, 2016
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4JDA
 | | Complex structure of abscisic acid receptor PYL3 with (-)-ABA | | 分子名称: | (2Z,4E)-5-[(1R)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL3 | | 著者 | Zhang, X, Wang, G, Chen, Z. | | 登録日 | 2013-02-24 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural Insights into the Abscisic Acid Stereospecificity by the ABA Receptors PYR/PYL/RCAR
Plos One, 8, 2013
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5K3H
 | | Crystals structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans, Apo form-II | | 分子名称: | Acyl-coenzyme A oxidase | | 著者 | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | | 登録日 | 2016-05-19 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5K3G
 | | Crystals structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans, Apo form-I | | 分子名称: | Acyl-coenzyme A oxidase | | 著者 | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | | 登録日 | 2016-05-19 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.859 Å) | | 主引用文献 | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5K3J
 | | Crystals structure of Acyl-CoA oxidase-2 in Caenorhabditis elegans bound with FAD, ascaroside-CoA, and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | | 登録日 | 2016-05-19 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5K3I
 | | Crystal structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans complexed with FAD and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | | 登録日 | 2016-05-19 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.683 Å) | | 主引用文献 | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6ID0
 | | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | | 登録日 | 2018-09-07 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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6ICZ
 | | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | | 登録日 | 2018-09-07 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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8SG1
 | | Cryo-EM structure of CMKLR1 signaling complex | | 分子名称: | CHOLESTEROL, Chemerin 9, Chemerin-like receptor 1, ... | | 著者 | Zhang, X, Zhang, C. | | 登録日 | 2023-04-11 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structural basis of G protein-Coupled receptor CMKLR1 activation and signaling induced by a chemerin-derived agonist.
Plos Biol., 21, 2023
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8T3V
 | | Cryo-EM structure of the DHA bound FFA1-Gq complex | | 分子名称: | CHOLESTEROL, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 1, ... | | 著者 | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | 登録日 | 2023-06-07 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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8T3Q
 | | Cryo-EM structure of the DHA bound FFA4-Gq complex | | 分子名称: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | 登録日 | 2023-06-07 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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8T3O
 | | Cryo-EM structure of the TUG-891 bound FFA4-Gq complex | | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, ... | | 著者 | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | 登録日 | 2023-06-07 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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8T3S
 | | Cryo-EM structure of the Butyrate bound FFA2-Gq complex | | 分子名称: | CHOLESTEROL, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | 登録日 | 2023-06-07 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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3AH5
 | | Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | | 著者 | Zhang, X, Zhang, J, Hu, Y, Zou, Q, Wang, D. | | 登録日 | 2010-04-14 | | 公開日 | 2011-04-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure and functional analysis of a flavin dependent thymidylate synthase from helicobacter pylori
To be Published
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3IYL
 | | Atomic CryoEM Structure of a Nonenveloped Virus Suggests How Membrane Penetration Protein is Primed for Cell Entry | | 分子名称: | Core protein VP6, MYRISTIC ACID, Outer capsid VP4, ... | | 著者 | Zhang, X, Jin, L, Fang, Q, Hui, W, Zhou, Z.H. | | 登録日 | 2010-02-02 | | 公開日 | 2010-05-12 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | 3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry.
Cell(Cambridge,Mass.), 141, 2010
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3J4U
 | | A new topology of the HK97-like fold revealed in Bordetella bacteriophage: non-covalent chainmail secured by jellyrolls | | 分子名称: | cementing protein, major capsid protein | | 著者 | Zhang, X, Guo, H, Jin, L, Czornyj, E, Hodes, A, Hui, W.H, Nieh, A.W, Miller, J.F, Zhou, Z.H. | | 登録日 | 2013-10-09 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution.
Elife, 2, 2013
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2CSE
 | | Features of Reovirus Outer-Capsid Protein mu1 Revealed by Electron and Image Reconstruction of the virion at 7.0-A Resolution | | 分子名称: | Minor core protein lambda 3, Sigma 2 protein, guanylyltransferase, ... | | 著者 | Zhang, X, Ji, Y, Zhang, L, Harrison, S.C, Marinescu, D.C, Nibert, M.L, Baker, T.S. | | 登録日 | 2005-05-21 | | 公開日 | 2005-10-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolution.
Structure, 13, 2005
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6IMB
 | | Crystal structure of PDE4D complexed with a novel inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ... | | 著者 | Zhang, X, Su, H, Xu, Y. | | 登録日 | 2018-10-22 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.549 Å) | | 主引用文献 | Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
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6IMI
 | | Crystal structure of PDE4D complexed with a novel inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 6-ethoxy-7-methoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ... | | 著者 | Zhang, X, Su, H, Xu, Y. | | 登録日 | 2018-10-23 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
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6IMD
 | | Crystal structure of PDE4D complexed with a novel inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ... | | 著者 | Zhang, X, Su, H, Xu, Y. | | 登録日 | 2018-10-22 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | | 主引用文献 | Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
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5XJC
 | | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | | 登録日 | 2017-04-30 | | 公開日 | 2017-07-05 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
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