1NQX

Crystal Structure of Lumazine Synthase from Aquifex aeolicus in Complex with Inhibitor: 3-(7-hydroxy-8-ribityllumazine-6-yl)propionic acid

Summary for 1NQX

Entry DOI	10.2210/pdb1nqx/pdb
Related	1NQU 1NQV 1NQW
Descriptor	6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION, 3-(7-HYDROXY-8-RIBITYLLUMAZINE-6-YL) PROPIONIC ACID, ... (4 entities in total)
Functional Keywords	lumazine synthase, aquifex aeolicus, inhibitor complex, vitamin biosynthesis, catalytic mechanism, transferase
Biological source	Aquifex aeolicus
Total number of polymer chains	5
Total formula weight	86042.43
Authors	Zhang, X.,Meining, W.,Cushman, M.,Haase, I.,Fischer, M.,Bacher, A.,Ladenstein, R. (deposition date: 2003-01-23, release date: 2004-01-23, Last modification date: 2024-02-14)
Primary citation	Zhang, X.,Meining, W.,Cushman, M.,Haase, I.,Fischer, M.,Bacher, A.,Ladenstein, R. A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus. J.Mol.Biol., 328:167-182, 2003 Cited by PubMed: 12684006 DOI: 10.1016/S0022-2836(03)00186-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation