5CA0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ca0 by Molmil](/molmil-images/mine/5ca0) | Crystal structure of T2R-TTL-Lexibulin complex | 分子名称: | 1-ethyl-3-[2-methoxy-4-(5-methyl-4-{[(1S)-1-(pyridin-3-yl)butyl]amino}pyrimidin-2-yl)phenyl]urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, Y, Yu, Y, Chen, Q, Yang, J. | 登録日 | 2015-06-29 | 公開日 | 2015-11-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery. Febs J., 283, 2016
|
|
1YO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yo5 by Molmil](/molmil-images/mine/1yo5) | Analysis of the 2.0A crystal structure of the protein-DNA complex of human PDEF Ets domain bound to the prostate specific antigen regulatory site | 分子名称: | Enhancer site of Prostate Specific Antigen Promoter Region, SAM pointed domain containing ets transcription factor | 著者 | Wang, Y, Feng, L, Said, M, Balderman, S, Fayazi, Z, Liu, Y, Ghosh, D, Gulick, A.M. | 登録日 | 2005-01-26 | 公開日 | 2005-05-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Analysis of the 2.0 A Crystal Structure of the Protein-DNA Complex of the Human PDEF Ets Domain Bound to the Prostate Specific Antigen Regulatory Site Biochemistry, 44, 2005
|
|
5CB4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cb4 by Molmil](/molmil-images/mine/5cb4) | Crystal structure of T2R-TTL-Tivantinib complex | 分子名称: | (3R,4R)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, Y, Yu, Y, Chen, Q, Yang, J. | 登録日 | 2015-06-30 | 公開日 | 2015-11-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.193 Å) | 主引用文献 | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery. Febs J., 283, 2016
|
|
7REI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rei by Molmil](/molmil-images/mine/7rei) | The crystal structure of nickel bound human ADO C18S C239S variant | 分子名称: | 2-aminoethanethiol dioxygenase, GLYCEROL, NICKEL (II) ION | 著者 | Wang, Y, Shin, I, Li, J, Liu, A. | 登録日 | 2021-07-12 | 公開日 | 2021-09-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal structure of human cysteamine dioxygenase provides a structural rationale for its function as an oxygen sensor. J.Biol.Chem., 297, 2021
|
|
8D5Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d5q by Molmil](/molmil-images/mine/8d5q) | TCR TG6 in complex with Ld-HF10 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Dense granule protein 6, HF10 peptide, ... | 著者 | Wang, Y, Dai, S. | 登録日 | 2022-06-05 | 公開日 | 2022-09-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Peptide Centric V beta Specific Germline Contacts Shape a Specialist T Cell Response. Front Immunol, 13, 2022
|
|
6O58
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o58 by Molmil](/molmil-images/mine/6o58) | Human MCU-EMRE complex, dimer of channel | 分子名称: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | 著者 | Wang, Y, Bai, X, Jiang, Y. | 登録日 | 2019-03-01 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter. Cell, 177, 2019
|
|
2F90
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f90 by Molmil](/molmil-images/mine/2f90) | Crystal structure of bisphosphoglycerate mutase in complex with 3-phosphoglycerate and AlF4- | 分子名称: | 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, TETRAFLUOROALUMINATE ION | 著者 | Wang, Y, Liu, L, Wei, Z, Gong, W. | 登録日 | 2005-12-05 | 公開日 | 2006-10-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase J.Biol.Chem., 281, 2006
|
|
6VI8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vi8 by Molmil](/molmil-images/mine/6vi8) | Observing a ring-cleaving dioxygenase in action through a crystalline lens - a superoxo bound structure | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate 3,4-dioxygenase, ... | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | 登録日 | 2020-01-12 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6VIA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6via by Molmil](/molmil-images/mine/6via) | Observing a ring-cleaving dioxygenase in action through a crystalline lens - a seven-membered lactone bound structure | 分子名称: | (2R,3E)-2-hydroxy-3-imino-2,3-dihydrooxepine-4-carboxylic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, ... | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | 登録日 | 2020-01-12 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.591 Å) | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6VI6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vi6 by Molmil](/molmil-images/mine/6vi6) | Observing a ring-cleaving dioxygenase in action through a crystalline lens - a substrate monodentately bound structure | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate 3,4-dioxygenase, ... | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | 登録日 | 2020-01-12 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6VI7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vi7 by Molmil](/molmil-images/mine/6vi7) | Probing extradiol dioxygenase mechanism in NAD(+) biosynthesis by viewing reaction cycle intermediates - a substrate bidentately bound structure | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate 3,4-dioxygenase, ... | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | 登録日 | 2020-01-12 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.617 Å) | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6VIB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vib by Molmil](/molmil-images/mine/6vib) | Observing a ring-cleaving dioxygenase in action through a crystalline lens - enol tautomers of ACMS bidentately bound structure | 分子名称: | (2Z,3Z)-2-[(2Z)-3-hydroxyprop-2-en-1-ylidene]-3-iminobutanedioic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, ... | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | 登録日 | 2020-01-12 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6VI9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vi9 by Molmil](/molmil-images/mine/6vi9) | Observing a ring-cleaving dioxygenase in action through a crystalline lens - an alkylperoxo bound structure | 分子名称: | (5R,6Z)-5-(hydroperoxy-kappaO)-5-(hydroxy-kappaO)-6-iminocyclohexa-1,3-diene-1-carboxylato(2-)iron, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, ... | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | 登録日 | 2020-01-12 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6X11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6x11 by Molmil](/molmil-images/mine/6x11) | Observing a ring-cleaving dioxygenase in action through a crystalline lens - an enol tautomer of ACMS monodentately bound structure | 分子名称: | (2Z,3Z)-2-[(2Z)-3-hydroxyprop-2-en-1-ylidene]-3-iminobutanedioic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, ... | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | 登録日 | 2020-05-17 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
1YJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yjx by Molmil](/molmil-images/mine/1yjx) | Crystal structure of human B type phosphoglycerate mutase | 分子名称: | CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1 | 著者 | Wang, Y, Wei, Z, Liu, L, Gong, W. | 登録日 | 2005-01-16 | 公開日 | 2005-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of human B-type phosphoglycerate mutase bound with citrate. Biochem.Biophys.Res.Commun., 331, 2005
|
|
6VI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vi5 by Molmil](/molmil-images/mine/6vi5) | Observing a ring-cleaving dioxygenase in action through a crystalline lens - a resting state structure | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, CHLORIDE ION, ... | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | 登録日 | 2020-01-12 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.604 Å) | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
5JZI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jzi by Molmil](/molmil-images/mine/5jzi) | Crystal structure of 1406 TCR bound to HLA-A2 with HCV 1406-1415 antigen peptide | 分子名称: | Beta-2-microglobulin, HCV1406 TCR alpha chain, HCV1406 TCR beta chain, ... | 著者 | Wang, Y, Piepenbrink, K.H, Baker, B.M. | 登録日 | 2016-05-16 | 公開日 | 2017-05-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | How an alloreactive T-cell receptor achieves peptide and MHC specificity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
2A9J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2a9j by Molmil](/molmil-images/mine/2a9j) | |
1YFK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yfk by Molmil](/molmil-images/mine/1yfk) | Crystal structure of human B type phosphoglycerate mutase | 分子名称: | CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1 | 著者 | Wang, Y, Wei, Z, Liu, L, Gong, W. | 登録日 | 2005-01-02 | 公開日 | 2005-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of human B-type phosphoglycerate mutase bound with citrate. Biochem.Biophys.Res.Commun., 331, 2005
|
|
8X1V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8x1v by Molmil](/molmil-images/mine/8x1v) | |
4ESP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4esp by Molmil](/molmil-images/mine/4esp) | |
6ON3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6on3 by Molmil](/molmil-images/mine/6on3) | A substrate bound structure of L-DOPA dioxygenase from Streptomyces sclerotialus | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,4-DIHYDROXYPHENYLALANINE, FE (II) ION, ... | 著者 | Wang, Y, Shin, I, Fu, Y, Colabroy, K, Liu, A. | 登録日 | 2019-04-19 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Crystal Structures of L-DOPA Dioxygenase fromStreptomyces sclerotialus. Biochemistry, 58, 2019
|
|
1M2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m2s by Molmil](/molmil-images/mine/1m2s) | Solution Structure of A New Potassium Channels Blocker from the Venom of Chinese Scorpion Buthus martensi Karsch | 分子名称: | Toxin BmTX3 | 著者 | Wang, Y, Li, M, Zhang, N, Wu, G, Hu, G, Wu, H. | 登録日 | 2002-06-25 | 公開日 | 2004-04-06 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of BmTx3B, a member of the scorpion toxin subfamily alpha-KTx 16 Proteins, 58, 2005
|
|
7K0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0o by Molmil](/molmil-images/mine/7k0o) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0k by Molmil](/molmil-images/mine/7k0k) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound | 分子名称: | 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|