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7DWN
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BU of 7dwn by Molmil
Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Predicted DNA-binding transcriptional regulator
著者Wang, W.W, Wu, H, He, J.H, Yu, F.
登録日2021-01-17
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism.
Int.J.Biol.Macromol., 183, 2021
7DWO
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BU of 7dwo by Molmil
Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members
分子名称: Predicted DNA-binding transcriptional regulator
著者Wang, W.W, Wu, H, He, J.H, Yu, F.
登録日2021-01-17
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism.
Int.J.Biol.Macromol., 183, 2021
7DQZ
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BU of 7dqz by Molmil
Crystal structure of SARS 3C-like protease in apo form
分子名称: 3C-like proteinase
著者Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J.
登録日2020-12-24
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
8HQI
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BU of 8hqi by Molmil
Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with inhibitor YH-53
分子名称: 3C-like proteinase nsp5, N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
著者Li, W.W, Zhang, J, Li, J.
登録日2022-12-13
公開日2023-12-20
最終更新日2025-01-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of main proteases of SARS-CoV-2 variants bound to a benzothiazole-based inhibitor.
Acta Biochim.Biophys.Sin., 55, 2023
8HQH
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BU of 8hqh by Molmil
Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with inhibitor YH-53
分子名称: 3C-like proteinase nsp5, N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
著者Zou, X.F, Zhang, J, Li, J.
登録日2022-12-13
公開日2023-12-20
最終更新日2025-01-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structures of main proteases of SARS-CoV-2 variants bound to a benzothiazole-based inhibitor.
Acta Biochim.Biophys.Sin., 55, 2023
4NJL
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BU of 4njl by Molmil
Crystal structure of middle east respiratory syndrome coronavirus S2 protein fusion core
分子名称: S protein, TRIETHYLENE GLYCOL
著者Zhu, Y, Lu, L, Qin, L, Ye, S, Jiang, S, Zhang, R.
登録日2013-11-10
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor.
Nat Commun, 5, 2014
8JJ2
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BU of 8jj2 by Molmil
Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab2G7 in one fab conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab2G7 Heavy Chain, ...
著者Wang, H, Zhu, S.
登録日2023-05-29
公開日2024-06-05
最終更新日2024-12-25
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis.
Nat.Struct.Mol.Biol., 31, 2024
8JJ1
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BU of 8jj1 by Molmil
Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab2G7 in two fab conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2G7 Heavy Chain, ...
著者Wang, H, Zhu, S.
登録日2023-05-29
公開日2024-06-05
最終更新日2024-12-25
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis.
Nat.Struct.Mol.Biol., 31, 2024
8JIZ
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BU of 8jiz by Molmil
Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab5F6 in two fab bind conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab5F6 Heavy Chain, ...
著者Wang, H, Zhu, S.
登録日2023-05-29
公開日2024-06-05
最終更新日2024-12-25
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis.
Nat.Struct.Mol.Biol., 31, 2024
8JJ0
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BU of 8jj0 by Molmil
Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab5F6 in one fab bind conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab5F6 Heavy Chain, ...
著者Wang, H, Zhu, S.
登録日2023-05-29
公開日2024-06-05
最終更新日2024-12-25
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis.
Nat.Struct.Mol.Biol., 31, 2024
7E3J
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BU of 7e3j by Molmil
Crystal structure of SARS-CoV-2 RBD binding to dog ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE2, Spike protein S1, ...
著者Zhang, Z, Zhang, Y.
登録日2021-02-08
公開日2021-04-07
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The molecular basis for SARS-CoV-2 binding to dog ACE2.
Nat Commun, 12, 2021
3HVA
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BU of 3hva by Molmil
Crystal structure of FimX GGDEF domain from Pseudomonas aeruginosa
分子名称: Protein FimX
著者Navarro, M.V.A.S, De, N, Bae, N, Sondermann, H.
登録日2009-06-15
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.042 Å)
主引用文献Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX.
Structure, 17, 2009
3HV8
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BU of 3hv8 by Molmil
Crystal structure of FimX EAL domain from Pseudomonas aeruginosa bound to c-di-GMP
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Protein FimX
著者Navarro, M.V.A.S, De, N, Bae, N, Sondermann, H.
登録日2009-06-15
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.445 Å)
主引用文献Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX.
Structure, 17, 2009
3M45
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BU of 3m45 by Molmil
Crystal structure of Ig1 domain of mouse SynCAM 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 2
著者Yue, L, Modis, Y.
登録日2010-03-10
公開日2010-09-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion.
J.Biol.Chem., 285, 2010
7TQQ
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BU of 7tqq by Molmil
Structure of human TREX1-DNA complex
分子名称: DNA (5'-D(P*TP*TP*GP*GP*CP*CP*GP*GP*CP*CP*AP*TP*C)-3'), Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQO
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BU of 7tqo by Molmil
Structure of human TREX1
分子名称: Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQN
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BU of 7tqn by Molmil
Structure of human TREX1
分子名称: Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQP
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BU of 7tqp by Molmil
Structure of human TREX1
分子名称: SULFATE ION, Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TTI
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BU of 7tti by Molmil
Human KCC1 bound with VU0463271 In an outward-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-cyclopropyl-N-(4-methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]acetamide, Solute carrier family 12 member 4
著者Zhao, Y.X, Cao, E.H.
登録日2022-02-01
公開日2022-06-29
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the human cation-chloride cotransport KCC1 in an outward-open state.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TTH
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BU of 7tth by Molmil
Human potassium-chloride cotransporter 1 in inward-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, POTASSIUM ION, Solute carrier family 12 member 4
著者Zhao, Y.X, Cao, E.H.
登録日2022-02-01
公開日2022-06-29
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structure of the human cation-chloride cotransport KCC1 in an outward-open state.
Proc.Natl.Acad.Sci.USA, 119, 2022
7FIK
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BU of 7fik by Molmil
The cryo-EM structure of the CR subunit from X. laevis NPC
分子名称: MGC154553 protein, MGC83295 protein, MGC83926 protein, ...
著者Shi, Y, Huang, G, Zhan, X.
登録日2021-07-31
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex.
Science, 376, 2022
7FIL
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BU of 7fil by Molmil
The cryo-EM structure of the NTD2 from the X. laevis Nup358
分子名称: Nup358 complex, clamps
著者Shi, Y, Zhan, X, Huang, G.
登録日2021-07-31
公開日2022-06-01
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex.
Science, 376, 2022
8ZC5
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BU of 8zc5 by Molmil
SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with D1F6 Fab, focused refinement of RBD region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D1F6 Fab, Light chain of D1F6 Fab, ...
著者Liu, B, Gao, X, Li, Z, Chen, Q, He, J, Xiong, X.
登録日2024-04-28
公開日2024-05-15
最終更新日2025-07-16
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike.
Cell Rep, 43, 2024
8ZC0
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BU of 8zc0 by Molmil
SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with 3 D1F6 Fabs (2 RBD up)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D1F6 Fab, ...
著者Liu, B, Gao, X, Li, Z, Chen, Q, He, J, Xiong, X.
登録日2024-04-28
公開日2024-05-15
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike.
Cell Rep, 43, 2024
8ZC3
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BU of 8zc3 by Molmil
SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with 3 D1F6 Fabs (1 RBD up)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D1F6 Fab, ...
著者Liu, B, Gao, X, Li, Z, Chen, Q, He, J, Xiong, X.
登録日2024-04-28
公開日2024-05-15
最終更新日2025-07-16
実験手法ELECTRON MICROSCOPY (4.69 Å)
主引用文献An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike.
Cell Rep, 43, 2024

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