7DQZ

Crystal structure of SARS 3C-like protease in apo form

Summary for 7DQZ

• Entry DOI: 10.2210/pdb7dqz/pdb
• Descriptor: 3C-like proteinase (2 entities in total)
• Functional Keywords: sars apo 3c-like protease, viral protein
• Biological source: Human SARS coronavirus (SARS-CoV)
• Total number of polymer chains: 2
• Total formula weight: 67753.27

Authors

Zhang, Y.T.,Gao, H.X.,Zhou, H.,Zhong, F.L.,Hu, X.H.,Zhou, X.L.,Lin, C.,Wang, Q.S.,Li, J.,Zhang, J. (deposition date: 2020-12-24, release date: 2021-09-29, Last modification date: 2023-11-29)

• Primary citation: Zhang, Y.,Gao, H.,Hu, X.,Wang, Q.,Zhong, F.,Zhou, X.,Lin, C.,Yang, Y.,Wei, J.,Du, W.,Huang, H.,Zhou, H.,He, W.,Zhang, H.,Zhang, Y.,McCormick, P.J.,Fu, J.,Wang, D.,Fu, Y.,Lu, X.,Zhang, T.,Duan, J.,Qin, B.,Jiang, H.,Luo, J.,Zhang, Y.,Chen, Q.,Luo, Q.,Cheng, L.,Zhang, Z.,Zhang, J.,Li, J.; Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.; J.Virol., 96:e0125321-e0125321, 2022; PubMed: 34586857; DOI: 10.1128/JVI.01253-21

Experimental method

X-RAY DIFFRACTION (1.99 Å)