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8EN1
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BU of 8en1 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 30
分子名称: GII.4 P domain, Nanobody 30
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EMY
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BU of 8emy by Molmil
Structure of GII.4 norovirus in complex with Nanobody 82
分子名称: 1,2-ETHANEDIOL, GII.4 P domain, Nanobody 82
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN2
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BU of 8en2 by Molmil
Structure of GII.10 norovirus in complex with Nanobody 34
分子名称: 1,2-ETHANEDIOL, GII.10 P domain, Nanobody 34
著者Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN3
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BU of 8en3 by Molmil
Structure of GII.17 norovirus in complex with Nanobody 45
分子名称: 1,2-ETHANEDIOL, Capsid protein VP1, Nanobody 45
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN0
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BU of 8en0 by Molmil
Structure of GII.17 norovirus in complex with Nanobody 7
分子名称: Capsid protein VP1, Nanobody 7
著者Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN6
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BU of 8en6 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 76
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GII.4 P domain, ...
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
6BOI
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BU of 6boi by Molmil
Crystal Structure of LdtMt2 (56-408) with a panipenem adduct at the active site cysteine-354
分子名称: (3S,5R)-5-[(2R,3R)-1,3-dihydroxybutan-2-yl]-3-({(3R)-1-[(1E)-ethanimidoyl]pyrrolidin-3-yl}sulfanyl)-L-proline, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Saavedra, H, Bianchet, M.A.
登録日2017-11-20
公開日2018-04-11
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Structures and Mechanism of Inhibition of Mycobacterium tuberculosis L,D-transpeptidase 2 by Panipenem
To Be Published
8QKY
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BU of 8qky by Molmil
Bacteriophage T5 dUTPase
分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL
著者Gabdulkhakov, A.G, Dzhus, U.F, Selikhanov, G.K, Glukhov, A.S.
登録日2023-09-18
公開日2024-01-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Bacteriophage T5 dUTPase: Combination of Common Enzymatic and Novel Functions.
Int J Mol Sci, 25, 2024
8QLD
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BU of 8qld by Molmil
Bacteriophage T5 dUTPase mutant with loop deletion (30-35 aa)
分子名称: CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL, ...
著者Gabdulkhakov, A.G, Dzhus, U.F, Selikhanov, G.K, Glukhov, A.S.
登録日2023-09-19
公開日2024-01-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Bacteriophage T5 dUTPase: Combination of Common Enzymatic and Novel Functions.
Int J Mol Sci, 25, 2024
5ER1
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BU of 5er1 by Molmil
A rational approach to the design of antihypertensives. X-ray studies of complexes between aspartic proteinases and aminoalcohol renin inhibitors
分子名称: ENDOTHIAPEPSIN, methyl N-[(2S,3S)-3-amino-2-hydroxy-5-methylhexyl]-L-valyl-L-isoleucyl-L-phenylalaninate
著者Cooper, J.B, Foundling, S.I, Blundell, T.L.
登録日1990-11-07
公開日1991-01-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Rational Approach to the Design of Antihypertensives. X-Ray Studies of Complexes between Aspartic Proteinases and Aminoalcohol Renin Inhibitors
Topics in Medicinal Chemistry, 1988
8JNC
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BU of 8jnc by Molmil
Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate 10-epi-maltophilin
分子名称: (1Z,3E,5S,8R,9S,10S,11R,13R,15R,16S,18Z,24S,25S)-11-ethyl-2,24-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.09,13.08,15.05,16]octacosa-1(2),3,18-triene-7,20,27,28-tetraone, Cytochrome P450, FORMIC ACID, ...
著者Zhang, Y.L, Zhang, L.P, Zhang, C.S.
登録日2023-06-06
公開日2023-11-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.
Angew.Chem.Int.Ed.Engl., 62, 2023
8JNP
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BU of 8jnp by Molmil
Crystal structure of cytochrome P450 CftA from Streptomyces torulosus NRRL B-3889, in complex with the substrate ikarugamycin
分子名称: (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione, Cytochrome P450 CftA, PROTOPORPHYRIN IX CONTAINING FE
著者Jiang, P, Zhang, L.P, Zhang, C.S.
登録日2023-06-06
公開日2023-11-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.
Angew.Chem.Int.Ed.Engl., 62, 2023
8JNQ
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BU of 8jnq by Molmil
Crystal structure of cytochrome P450 CftA from Streptomyces torulosus NRRL B-3889, in complex with a substrate compound c
分子名称: (1Z,3E,5E,7S,8R,10S,11R,13R,15R,16E,18E,25S)-11-ethyl-2,7-dihydroxy-10-methyl-21,26-diazatetracyclo[23.2.1.09,13.08,15]octacosa-1(2),3,5,16,18-pentaene-20,27,28-trione, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Jiang, P, Zhang, L.P, Zhang, C.S.
登録日2023-06-06
公開日2023-11-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.
Angew.Chem.Int.Ed.Engl., 62, 2023
8JOO
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BU of 8joo by Molmil
Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate ikarugamycin
分子名称: (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione, Cytochrome P450, FORMIC ACID, ...
著者Zhang, Y.L, Zhang, L.P, Zhang, C.S.
登録日2023-06-08
公開日2023-11-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.
Angew.Chem.Int.Ed.Engl., 62, 2023
8JNO
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BU of 8jno by Molmil
Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate 10-epi-deOH-HSAF
分子名称: (1Z,3E,5S,7S,8R,9S,10S,11R,13R,15R,16S,18Z,25S)-11-ethyl-2,7-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.09,13.08,15.05,16]octacosa-1(2),3,18-triene-20,27,28-trione, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhang, Y.L, Zhang, L.P, Zhang, C.S.
登録日2023-06-06
公開日2023-11-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.
Angew.Chem.Int.Ed.Engl., 62, 2023
8JUA
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BU of 8jua by Molmil
Multifunctional cytochrome P450 enzyme IkaD from Streptomyces sp. ZJ306, in complex with epoxyikarugamycin
分子名称: (1Z,3E,5S,7R,8R,10R,11R,12S,13R,15S,16R,17S,19Z,26S)-11-ethyl-2-hydroxy-10-methyl-22,27-diaza-14 oxahexacyclo[24.2.1.05,17.07,16.013,15.08,12]nonacosa-1(2),3,19-triene-21,28,29-trione, Cytochrome P450, FORMIC ACID, ...
著者Zhang, Y.L, Zhang, L.P, Zhang, C.S.
登録日2023-06-26
公開日2023-11-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.00001121 Å)
主引用文献A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.
Angew.Chem.Int.Ed.Engl., 62, 2023
3UGD
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BU of 3ugd by Molmil
Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Protein kinase C delta type, ...
著者Shanmugasundararaj, S, Stehle, T, Miller, K.W.
登録日2011-11-02
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
Biophys.J., 103, 2012
6ILJ
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BU of 6ilj by Molmil
Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 5.5
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Gao, G.F, Liu, S, Zhao, X, Peng, R.
登録日2018-10-18
公開日2019-05-15
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILL
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BU of 6ill by Molmil
Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 5.5
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Gao, G.F, Liu, S, Zhao, X, Peng, R.
登録日2018-10-19
公開日2019-05-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
8YWX
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BU of 8ywx by Molmil
the complex structure of the H4B6 Fab with the RBD of Omicron BA.5 S protein
分子名称: H4B6 Fab's heavy chain, H4B6 Fab's light chain, Spike protein S2'
著者Xia, L.Y, Zhang, Y.Y, Zhou, Q.
登録日2024-04-01
公開日2024-07-31
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献A novel bispecific antibody targeting two overlapping epitopes in RBD improves neutralizing potency and breadth against SARS-CoV-2.
Emerg Microbes Infect, 13, 2024
8YWW
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BU of 8yww by Molmil
The structure of HKU1-B S protein with bsAb1
分子名称: H4B6 heavy chain, H4B6 light chain, Spike glycoprotein, ...
著者Xia, L.Y, Zhang, Y.Y, Zhou, Q.
登録日2024-04-01
公開日2024-07-31
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献A novel bispecific antibody targeting two overlapping epitopes in RBD improves neutralizing potency and breadth against SARS-CoV-2.
Emerg Microbes Infect, 13, 2024
6ILO
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BU of 6ilo by Molmil
Cryo-EM structure of empty Echovirus 6 particle at PH 7.4
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3
著者Gao, G.F, Liu, S, Zhao, X, Peng, R.
登録日2018-10-19
公開日2019-05-15
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
3FAA
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BU of 3faa by Molmil
Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
分子名称: N-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide, PHOSPHATE ION, TGF-beta receptor type-1
著者Boriack-Sjodin, P.A, Fitch, C.
登録日2008-11-16
公開日2009-01-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献2-Aminoimidazoles inhibitors of TGF-beta receptor 1.
Bioorg.Med.Chem.Lett., 19, 2009
5WWK
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BU of 5wwk by Molmil
Highly stable green fluorescent protein
分子名称: Green fluorescent protein
著者Sriram, R, George, A, Kesavan, M, Jaimohan, S.M, Kamini, N.R, Easwaramoorthi, S, Ganesh, S, Gunasekaran, K, Ayyadurai, N.
登録日2017-01-02
公開日2017-12-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.199 Å)
主引用文献Excited State Electronic Interconversion and Structural Transformation of Engineered Red-Emitting Green Fluorescent Protein Mutant.
J.Phys.Chem.B, 123, 2019
8XC4
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BU of 8xc4 by Molmil
Nipah virus attachment glycoprotein head domain in complex with a broadly neutralizing antibody 1E5
分子名称: 1E5-VH, 1E5-VL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Fan, P.F, Yu, C.M, Chen, W.
登録日2023-12-08
公開日2024-01-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer.
Nat Commun, 15, 2024

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件を2025-07-09に公開中

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