6BOI

Crystal Structure of LdtMt2 (56-408) with a panipenem adduct at the active site cysteine-354

Summary for 6BOI

• Entry DOI: 10.2210/pdb6boi/pdb
• Related: 3TUR 3TX4 3U1P 3U1Q 3VYN 4GSU 5D7H 5DC2 5DCC
• Descriptor: Putative conserved lipoprotein LppS, (3S,5R)-5-[(2R,3R)-1,3-dihydroxybutan-2-yl]-3-({(3R)-1-[(1E)-ethanimidoyl]pyrrolidin-3-yl}sulfanyl)-L-proline, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: l, d-transpeptidase 2, carbapenem, complex, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
• Total number of polymer chains: 2
• Total formula weight: 77579.96

Authors

Saavedra, H.,Bianchet, M.A. (deposition date: 2017-11-20, release date: 2018-04-11, Last modification date: 2023-10-04)

• Primary citation: Saavedra, H.,Bianchet, M.A.; Structures and Mechanism of Inhibition of Mycobacterium tuberculosis L,D-transpeptidase 2 by Panipenem; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.102 Å)