4WO3
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1G87
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![BU of 1g87 by Molmil](/molmil-images/mine/1g87) | THE CRYSTAL STRUCTURE OF ENDOGLUCANASE 9G FROM CLOSTRIDIUM CELLULOLYTICUM | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, ENDOCELLULASE 9G, ... | 著者 | Mandelman, D, Belaich, A, Belaich, J.P, Aghajari, N, Driguez, H, Haser, R. | 登録日 | 2000-11-16 | 公開日 | 2003-07-15 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-Ray Crystal Structure of the Multidomain Endoglucanase Cel9G from Clostridium
cellulolyticum Complexed with Natural and Synthetic Cello-Oligosaccharides J.BACTERIOL., 185, 2003
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1G8Q
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![BU of 1g8q by Molmil](/molmil-images/mine/1g8q) | CRYSTAL STRUCTURE OF HUMAN CD81 EXTRACELLULAR DOMAIN, A RECEPTOR FOR HEPATITIS C VIRUS | 分子名称: | CD81 ANTIGEN, EXTRACELLULAR DOMAIN | 著者 | Kitadokoro, K, Bolognesi, M, Bordo, D, Grandi, G, Galli, G, Petracca, R, Falugi, F. | 登録日 | 2000-11-20 | 公開日 | 2001-02-21 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs. EMBO J., 20, 2001
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1TVT
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4WH0
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![BU of 4wh0 by Molmil](/molmil-images/mine/4wh0) | YcaC from Pseudomonas aeruginosa with S-mercaptocysteine active site cysteine | 分子名称: | CHLORIDE ION, Putative hydrolase | 著者 | Groftehauge, M.K, Truan, D, Vasil, A, Denny, P.W, Vasil, M.L, Pohl, E. | 登録日 | 2014-09-19 | 公開日 | 2015-07-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.563 Å) | 主引用文献 | Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct. Int J Mol Sci, 16, 2015
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1TOF
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![BU of 1tof by Molmil](/molmil-images/mine/1tof) | THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES | 分子名称: | THIOREDOXIN H | 著者 | Mittard, V, Blackledge, M.J, Stein, M, Jacquot, J.-P, Marion, D, Lancelin, J.-M. | 登録日 | 1996-05-30 | 公開日 | 1996-12-07 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of an oxidised thioredoxin h from the eukaryotic green alga Chlamydomonas reinhardtii. Eur.J.Biochem., 243, 1997
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6ODB
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![BU of 6odb by Molmil](/molmil-images/mine/6odb) | Crystal structure of HDAC8 in complex with compound 3 | 分子名称: | GLYCEROL, Histone deacetylase 8, N-{2-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]phenyl}-2-phenoxybenzamide, ... | 著者 | Zheng, X, Conti, C, Caravella, J, Zablocki, M.-M, Bair, K, Barczak, N, Han, B, Lancia Jr, D, Liu, C, Martin, M, Ng, P.Y, Rudnitskaya, A, Thomason, J.J, Garcia-Dancey, R, Hardy, C, Lahdenranta, J, Leng, C, Li, P, Pardo, E, Saldahna, A, Tan, T, Toms, A.V, Yao, L, Zhang, C. | 登録日 | 2019-03-26 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-based Discovery of Novel N-(E)-N-Hydroxy-3-(2-(2-oxoimidazolidin-1-yl)phenyl)acrylamides as Potent and Selective HDAC8 inhibitors To Be Published
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1GKG
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![BU of 1gkg by Molmil](/molmil-images/mine/1gkg) | Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35) | 分子名称: | COMPLEMENT RECEPTOR TYPE 1 | 著者 | Smith, B.O, Mallin, R.L, Krych-Goldberg, M, Wang, X, Hauhart, R.E, Bromek, K, Uhrin, D, Atkinson, J.P, Barlow, P.N. | 登録日 | 2001-08-14 | 公開日 | 2002-04-18 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor Cell(Cambridge,Mass.), 108, 2002
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8D8O
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![BU of 8d8o by Molmil](/molmil-images/mine/8d8o) | Cryo-EM structure of substrate unbound PAPP-A | 分子名称: | Pappalysin-1, ZINC ION | 著者 | Judge, R.A, Jain, R, Hao, Q, Ouch, C, Sridar, J, Smith, C.L, Wang, J.C.K, Eaton, D. | 登録日 | 2022-06-08 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition Nat Commun, 13, 2022
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4WJB
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![BU of 4wjb by Molmil](/molmil-images/mine/4wjb) | X-ray crystal structure of a putative amidohydrolase/peptidase from Burkholderia cenocepacia | 分子名称: | 1,2-ETHANEDIOL, Putative amidohydrolase/peptidase, SULFATE ION, ... | 著者 | Lukacs, C.M, Dranow, D.M, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2014-09-29 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | X-ray crystal structure of a putative amidohydrolase/peptidase from Burkholderia cenocepacia To Be Published
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6OEX
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![BU of 6oex by Molmil](/molmil-images/mine/6oex) | Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor 3-(2-{1-[2-(Piperidin-4-yl)ethyl]-1H-indol-5-yl}-5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3- thiazol-4-yl)-N-(2,2,2-trifluoroethyl)prop-2-yn-1-amine | 分子名称: | 3-(2-{1-[2-(piperidin-4-yl)ethyl]-1H-indol-5-yl}-5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-4-yl)-N-(2,2,2-trifluoroethyl)prop-2-yn-1-amine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Halgas, O, De Gasparo, R, Harangozo, D, Krauth-Siegel, R.L, Diederich, F, Pai, E.F. | 登録日 | 2019-03-28 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Targeting a Large Active Site: Structure-Based Design of Nanomolar Inhibitors of Trypanosoma brucei Trypanothione Reductase. Chemistry, 25, 2019
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1FVT
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![BU of 1fvt by Molmil](/molmil-images/mine/1fvt) | THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH AN OXINDOLE INHIBITOR | 分子名称: | 4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzene-1-sulfonamide, CELL DIVISION PROTEIN KINASE 2 | 著者 | Davis, S.T, Benson, B.G, Bramson, H.N, Chapman, D.E, Dickerson, S.H, Dold, K.M, Eberwein, D.J, Edelstein, M, Frye, S.V, Gampe Jr, R.T, Griffin, R.J, Harris, P.A, Hassell, A.M, Holmes, W.D, Hunter, R.N, Knick, V.B, Lackey, K, Lovejoy, B, Luzzio, M.J, Murray, D, Parker, P, Rocque, W.J, Shewchuk, L, Veal, J.M, Walker, D.H, Kuyper, L.K. | 登録日 | 2000-09-20 | 公開日 | 2001-01-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science, 291, 2001
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4WKU
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![BU of 4wku by Molmil](/molmil-images/mine/4wku) | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ | 分子名称: | Acyl-homoserine lactone acylase PvdQ, GLYCEROL, hexyl(trihydroxy)borate(1-) | 著者 | Wu, R, Clevenger, K.D, Fast, W, Liu, D. | 登録日 | 2014-10-03 | 公開日 | 2014-11-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ. Biochemistry, 53, 2014
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4WMD
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![BU of 4wmd by Molmil](/molmil-images/mine/4wmd) | Crystal structure of catalytically inactive MERS-CoV 3CL protease (C148A) in spacegroup C2221 | 分子名称: | DI(HYDROXYETHYL)ETHER, ORF1a, PENTAETHYLENE GLYCOL, ... | 著者 | Lountos, G.T, Needle, D, Waugh, D.S. | 登録日 | 2014-10-08 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.585 Å) | 主引用文献 | Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity. Acta Crystallogr.,Sect.D, 71, 2015
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3T0Q
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![BU of 3t0q by Molmil](/molmil-images/mine/3t0q) | Motor Domain Structure of the Kar3-like kinesin from Ashbya gossypii | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, AGR253Wp, ... | 著者 | Duan, D, Hnatchuk, D.J, Brenner, J, Davis, D, Allingham, J.S. | 登録日 | 2011-07-20 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of the Kar3-like kinesin motor domain from the filamentous fungus Ashbya gossypii. Proteins, 80, 2012
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6PSC
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![BU of 6psc by Molmil](/molmil-images/mine/6psc) | Antibody scFv-M204 trimeric state | 分子名称: | scFv-M204 antibody | 著者 | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | 登録日 | 2019-07-12 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
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6PZN
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6PXF
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![BU of 6pxf by Molmil](/molmil-images/mine/6pxf) | Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution | 分子名称: | 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonic acid, Cathepsin K | 著者 | Law, S, Aguda, A.H, Nguyen, N.T, Brayer, G.D, Bromme, D. | 登録日 | 2019-07-25 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution To Be Published
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1G0W
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4OAL
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![BU of 4oal by Molmil](/molmil-images/mine/4oal) | Crystal structure of maize cytokinin oxidase/dehydrogenase 4 (ZmCKO4) in complex with phenylurea inhibitor CPPU in alternative spacegroup | 分子名称: | 1-(2-chloropyridin-4-yl)-3-phenylurea, Cytokinin dehydrogenase 4, DIMETHYL SULFOXIDE, ... | 著者 | Kopecny, D, Morera, S, Vigouroux, A, Koncitikova, R. | 登録日 | 2014-01-05 | 公開日 | 2015-04-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Kinetic and structural investigation of the cytokinin oxidase/dehydrogenase active site. Febs J., 283, 2016
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1G84
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![BU of 1g84 by Molmil](/molmil-images/mine/1g84) | THE SOLUTION STRUCTURE OF THE C EPSILON2 DOMAIN FROM IGE | 分子名称: | IMMUNOGLOBULIN E | 著者 | McDonnell, J.M, Cowburn, D, Gould, H.J, Sutton, B.J, Calvert, R, Beavil, R.E, Beavil, A.J, Henry, A.J. | 登録日 | 2000-11-16 | 公開日 | 2001-05-16 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha. Nat.Struct.Biol., 8, 2001
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4Y6W
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6Q3Z
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![BU of 6q3z by Molmil](/molmil-images/mine/6q3z) | Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 16k | 分子名称: | (7~{R})-2-[[2-ethoxy-4-(1-methylpiperidin-4-yl)phenyl]amino]-7-ethyl-5-methyl-8-[(4-methylthiophen-2-yl)methyl]-7~{H}-pteridin-6-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | 著者 | Heidenreich, D, Watts, E, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Knapp, S, Hoelder, S, Structural Genomics Consortium (SGC) | 登録日 | 2018-12-04 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity. J.Med.Chem., 62, 2019
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4Y62
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![BU of 4y62 by Molmil](/molmil-images/mine/4y62) | AAGlyB in complex with amino-acid analogues | 分子名称: | 5'-deoxy-5'-{[(2R)-3-hydroxy-2-(4-phenyl-1H-1,2,3-triazol-1-yl)propanoyl]amino}uridine, Histo-blood group ABO system transferase, octyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside | 著者 | Wang, S, Cuesta-Seijo, J.A, Striebeck, A, Lafont, D, Palcic, M.M, Vidal, S. | 登録日 | 2015-02-12 | 公開日 | 2015-09-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Design of Glycosyltransferase Inhibitors: Serine Analogues as Pyrophosphate Surrogates? Chempluschem, 80, 2015
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1GEF
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![BU of 1gef by Molmil](/molmil-images/mine/1gef) | Crystal structure of the archaeal holliday junction resolvase HJC | 分子名称: | HOLLIDAY JUNCTION RESOLVASE, SULFATE ION | 著者 | Nishino, T, Komori, K, Tsuchiya, D, Ishino, Y, Morikawa, K. | 登録日 | 2000-11-08 | 公開日 | 2001-03-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the archaeal holliday junction resolvase Hjc and implications for DNA recognition. Structure, 9, 2001
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