Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)

Summary for 1GKG

DescriptorCOMPLEMENT RECEPTOR TYPE 1 (1 entity in total)
Functional Keywordscomplement, module, scr, sushi
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMembrane; Single-pass type I membrane protein P17927
Total number of polymer chains1
Total molecular weight14706.58
Smith, B.O.,Mallin, R.L.,Krych-Goldberg, M.,Wang, X.,Hauhart, R.E.,Bromek, K.,Uhrin, D.,Atkinson, J.P.,Barlow, P.N. (deposition date: 2001-08-14, release date: 2002-04-18, Last modification date: 2011-07-13)
Primary citation
Smith, B.,Mallin, R.,Krych-Goldberg, M.,Wang, X.,Hauhart, R.,Bromek, K.,Uhrin, D.,Atkinson, J.,Barlow, P.
Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
Cell(Cambridge,Mass.), 108:769-, 2002
PubMed: 11955431 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(02)00672-4
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers32 15.5% 5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload
PDB entries from 2020-11-25