1G0W

CRYSTAL STRUCTURE OF BOVINE RETINAL CREATINE KINASE

Summary for 1G0W

• Entry DOI: 10.2210/pdb1g0w/pdb
• Descriptor: CREATINE KINASE, SULFATE ION (3 entities in total)
• Functional Keywords: brain-type creatine kinase, guanidino kinase cellular energy metabolism, transferase
• Biological source: Bos taurus (cattle)
• Cellular location: Cytoplasm (By similarity): Q9XSC6
• Total number of polymer chains: 1
• Total formula weight: 42826.22

Authors

Tisi, D.,Bax, B.,Loew, A. (deposition date: 2000-10-09, release date: 2001-02-07, Last modification date: 2024-02-07)

Primary citation

Tisi, D.,Bax, B.,Loew, A.
The three-dimensional structure of cytosolic bovine retinal creatine kinase.
Acta Crystallogr.,Sect.D, 57:187-193, 2001

PubMed Abstract: Creatine kinase (CK) catalyses the reversible transfer of the phosphate moiety from phosphocreatine (PCr) to ADP, generating creatine and ATP. The crystal structure of a cytosolic brain-type creatine kinase is reported at 2.3 A. The biological dimer sits on a crystallographic twofold axis. The N-terminal residues of both subunits come very close to the crystallographic twofold at the dimer interface. The electron density observed is consistent with two alternative conformations for the N-termini, as previously found for chicken brain-type creatine kinase.

PubMed: 11173463
DOI: 10.1107/S0907444900015614

Experimental method

X-RAY DIFFRACTION (2.3 Å)