7D8T
 
 | | MITF bHLHLZ complex with M-box DNA | | 分子名称: | DNA (5'-D(*TP*GP*TP*AP*AP*CP*AP*TP*GP*TP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*AP*CP*AP*CP*AP*TP*GP*TP*TP*AP*CP*AP*G)-3'), Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit | | 著者 | Guo, M, Fang, P, Wang, J. | | 登録日 | 2020-10-09 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
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7D8R
 | | MITF HLHLZ structure | | 分子名称: | Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit | | 著者 | Guo, M, Fang, P, Wang, J. | | 登録日 | 2020-10-09 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
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7D8S
 | | MITF bHLHLZ apo structure | | 分子名称: | Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit, SULFATE ION | | 著者 | Guo, M, Fang, P, Wang, J. | | 登録日 | 2020-10-09 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
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5XKU
 | | Crystal structure of hemagglutinin globular head from an H7N9 influenza virus in complex with a neutralizing antibody HNIgGA6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HNIgGA6 heavy chain, HNIgGA6 light chain, ... | | 著者 | Chen, C, Wang, J, Wang, W, Gao, X, Cui, S, Jin, Q. | | 登録日 | 2017-05-09 | | 公開日 | 2017-11-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural Insight into a Human Neutralizing Antibody against Influenza Virus H7N9
J. Virol., 92, 2018
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4EBZ
 | | Crystal structure of the ectodomain of a receptor like kinase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin elicitor receptor kinase 1, ... | | 著者 | Chai, J, Liu, T, Han, Z, She, J, Wang, J. | | 登録日 | 2012-03-26 | | 公開日 | 2012-06-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | | 主引用文献 | Chitin-induced dimerization activates a plant immune receptor.
Science, 336, 2012
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4EBY
 | | Crystal structure of the ectodomain of a receptor like kinase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin elicitor receptor kinase 1, ... | | 著者 | Chai, J, Liu, T, Han, Z, She, J, Wang, J. | | 登録日 | 2012-03-25 | | 公開日 | 2012-06-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Chitin-induced dimerization activates a plant immune receptor.
Science, 336, 2012
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1R5H
 | | Crystal Structure of MetAP2 complexed with A320282 | | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE | | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | | 登録日 | 2003-10-10 | | 公開日 | 2004-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
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4NCB
 | | Structure of Thermus thermophilus Argonaute bound to guide DNA and 19-mer target DNA with Mg2+ | | 分子名称: | 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*C)-3', 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', ... | | 著者 | Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y. | | 登録日 | 2013-10-24 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | | 主引用文献 | Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1R58
 | | Crystal Structure of MetAP2 complexed with A357300 | | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE | | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Ericken, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | | 登録日 | 2003-10-09 | | 公開日 | 2004-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
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4Z0B
 | | Crystal Structure of the Fab Fragment of Anti-ofloxacin Antibody and Exploration Its Receptor Binding Site | | 分子名称: | PHOSPHATE ION, antibody heavy chain, antibody light chain | | 著者 | He, K, Du, X, Sheng, W, Zhou, X, Wang, J, Wang, S. | | 登録日 | 2015-03-26 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal Structure of the Fab Fragment of an Anti-ofloxacin Antibody and Exploration of Its Specific Binding.
J.Agric.Food Chem., 64, 2016
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3CMZ
 | | TEM-1 Class-A beta-lactamase L201P mutant apo structure | | 分子名称: | Beta-lactamase TEM, PHOSPHATE ION | | 著者 | Marciano, D.C, Wang, X, Wang, J, Chen, Y, Thomas, V.L, Shoichet, B.K, Palzkill, T. | | 登録日 | 2008-03-24 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Genetic and structural characterization of an L201P global suppressor substitution in TEM-1 beta-lactamase
J.Mol.Biol., 384, 2008
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3QNO
 | | RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite 3tCo | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA Polymerase, ... | | 著者 | Xia, S, Wang, M, Wang, J, Konigsberg, W.H. | | 登録日 | 2011-02-08 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase.
Biochemistry, 51, 2012
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5ZM7
 | | Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution | | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | | 著者 | Dong, J, Wang, J, Wu, J.W. | | 登録日 | 2018-04-01 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
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5IRI
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3QNN
 | | RB69 DNA Polymerase (Y567A) Ternary Complex with dGT Opposite 3tCo | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA Primer, ... | | 著者 | Xia, S, Wang, M, Wang, J, Konigsberg, W.H. | | 登録日 | 2011-02-08 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase.
Biochemistry, 51, 2012
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1R5G
 | | Crystal Structure of MetAP2 complexed with A311263 | | 分子名称: | (2S,3R)-3-AMINO-2-HYDROXY-5-(ETHYLSULFANYL)PENTANOYL-((S)-(-)-(1-NAPHTHYL)ETHYL)AMIDE, MANGANESE (II) ION, Methionine aminopeptidase 2 | | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | | 登録日 | 2003-10-10 | | 公開日 | 2004-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
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5ZM5
 | | Crystal structure of human ORP1-ORD in complex with cholesterol at 2.6 A resolution | | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | | 著者 | Dong, J, Wang, J, Wu, J.W. | | 登録日 | 2018-04-01 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
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1IH7
 | | High-Resolution Structure of Apo RB69 DNA Polymerase | | 分子名称: | DNA POLYMERASE, GUANOSINE, POTASSIUM ION | | 著者 | Franklin, M.C, Wang, J, Steitz, T.A. | | 登録日 | 2001-04-18 | | 公開日 | 2001-06-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure of the Replicating Complex of a Pol alpha Family DNA Polymerase
Cell(Cambridge,Mass.), 105, 2001
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4N76
 | | Structure of Thermus thermophilus Argonaute bound to guide DNA and cleaved target DNA with Mn2+ | | 分子名称: | 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', Argonaute, ... | | 著者 | Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y. | | 登録日 | 2013-10-15 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4N41
 | | Structure of Thermus thermophilus Argonaute bound to guide DNA and 15-mer target DNA | | 分子名称: | 5'-D(*AP*AP*CP*CP*TP*AP*CP*TP*GP*CP*CP*TP*CP*G)-3', 5'-D(P*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*T*GP*TP*AP*TP*AP*GP*T)-3', ... | | 著者 | Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y. | | 登録日 | 2013-10-08 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.248 Å) | | 主引用文献 | Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6IJZ
 | | Structure of a plant cation channel | | 分子名称: | Calcium permeable stress-gated cation channel 1 | | 著者 | Sun, L, Wang, J, Liu, X. | | 登録日 | 2018-10-12 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2.
Nat Commun, 9, 2018
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2PMY
 | | EF-hand domain of human RASEF | | 分子名称: | CALCIUM ION, RAS and EF-hand domain-containing protein, SULFATE ION, ... | | 著者 | Zhu, H, Shen, Y, Wang, J, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2007-04-23 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | EF-hand domain of human RASEF
To be Published
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1EFG
 | | THE CRYSTAL STRUCTURE OF ELONGATION FACTOR G COMPLEXED WITH GDP, AT 2.7 ANGSTROMS RESOLUTION | | 分子名称: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Czworkowski, J, Wang, J, Steitz, T.A, Moore, P.B. | | 登録日 | 1994-10-17 | | 公開日 | 1995-02-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution.
EMBO J., 13, 1994
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4QPG
 | | Crystal structure of empty hepatitis A virus | | 分子名称: | CHLORIDE ION, Capsid protein VP0, Capsid protein VP1, ... | | 著者 | Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | | 登録日 | 2014-06-23 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Hepatitis A virus and the origins of picornaviruses.
Nature, 517, 2015
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1JE9
 | | NMR SOLUTION STRUCTURE OF NT2 | | 分子名称: | SHORT NEUROTOXIN II | | 著者 | Cheng, Y, Wang, W, Wang, J. | | 登録日 | 2001-06-16 | | 公開日 | 2001-07-04 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure-function relationship of three neurotoxins from the venom of Naja kaouthia: a comparison between the NMR-derived structure of NT2 with its homologues, NT1 and NT3
BIOCHIM.BIOPHYS.ACTA, 1594, 2002
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