7X8O
 
 | | NMR Solution Structure of the 2:1 Coptisine-KRAS-G4 Complex | | 分子名称: | 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, DNA (24-MER) | | 著者 | Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y. | | 登録日 | 2022-03-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
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7X8N
 | | NMR Solution Structure of the Wild-type Bulge-containing KRAS-G4 | | 分子名称: | DNA (24-mer) | | 著者 | Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y. | | 登録日 | 2022-03-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
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7WGW
 | | NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, DNA (20-MER) | | 著者 | Wang, K.B, Liu, Y, Li, Y, Li, J, Dickerhoff, J, Yang, M.H, Yang, D, Kong, L.Y. | | 登録日 | 2021-12-29 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.
J.Am.Chem.Soc., 144, 2022
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7WI7
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6J0Z
 | | Crystal structure of AlpK | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative angucycline-like polyketide oxygenase | | 著者 | Wang, W, Liu, Y, Liang, H. | | 登録日 | 2018-12-27 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.889 Å) | | 主引用文献 | Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin
Biochem. Biophys. Res. Commun., 510, 2019
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6MZC
 | | Human TFIID BC core | | 分子名称: | Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 2, ... | | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | | 登録日 | 2018-11-05 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
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6MZM
 | | Human TFIID bound to promoter DNA and TFIIA | | 分子名称: | SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | | 登録日 | 2018-11-05 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
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6MZD
 | | Human TFIID Lobe A canonical | | 分子名称: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | | 登録日 | 2018-11-05 | | 公開日 | 2018-11-28 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
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7DQO
 | | Marsupenaeus japonicus ferritin mutant-D132R | | 分子名称: | FE (III) ION, Ferritin | | 著者 | Tan, X, Liu, Y, Zang, J, Zhang, T, Zhao, G. | | 登録日 | 2020-12-24 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Hyperthermostability of prawn ferritin nanocage facilitates its application as a robust nanovehicle for nutraceuticals.
Int.J.Biol.Macromol., 191, 2021
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7DQP
 | | Thermal treated Marsupenaeus japonicus ferritin | | 分子名称: | Ferritin | | 著者 | Tan, X, Liu, Y, Zang, J, Zhang, T, Zhao, G. | | 登録日 | 2020-12-24 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | | 主引用文献 | Hyperthermostability of prawn ferritin nanocage facilitates its application as a robust nanovehicle for nutraceuticals.
Int.J.Biol.Macromol., 191, 2021
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7E29
 | | Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP | | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Li, J, Smolle, M, Liang, H, Liu, Y. | | 登録日 | 2021-02-05 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function.
Nucleic Acids Res., 50, 2022
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7YEH
 | | Cryo-EM structure of human OGT-OGA complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... | | 著者 | Lu, P, Liu, Y, Yu, H, Gao, H. | | 登録日 | 2022-07-05 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | | 主引用文献 | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Nat Commun, 14, 2023
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7YEA
 | | Human O-GlcNAc transferase Dimer | | 分子名称: | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | | 著者 | Gao, H, Lu, P, Liu, Y. | | 登録日 | 2022-07-05 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Nat Commun, 14, 2023
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5UY1
 | | X-ray crystal structure of apo Halotag | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Haloalkane dehalogenase | | 著者 | Dunham, N.P, Boal, A.K. | | 登録日 | 2017-02-23 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification.
Biochemistry, 56, 2017
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5UXZ
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5D2R
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8I6Y
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6FKQ
 | | THE CRYSTAL STRUCTURE OF A FRAGMENT OF NETRIN-1 IN COMPLEX WITH A FRAGMENT OF DRAXIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Bhowmick, T, Meijers, R. | | 登録日 | 2018-01-24 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.
Neuron, 97, 2018
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5NS3
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5NS4
 | | Crystal structures of Cy3 cyanine fluorophores stacked onto the end of double-stranded RNA | | 分子名称: | 3-[(2~{Z})-2-[(~{E})-3-[3,3-dimethyl-1-(3-oxidanylpropyl)indol-1-ium-2-yl]prop-2-enylidene]-3,3-dimethyl-indol-1-yl]propan-1-ol, 50S ribosomal protein L5, MAGNESIUM ION, ... | | 著者 | Liu, Y.J, Lilley, D.M.J. | | 登録日 | 2017-04-25 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Cyanine Fluorophores Stacked onto the End of Double-Stranded RNA.
Biophys. J., 113, 2017
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7R4H
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4DVF
 | | Crystal structure of BACE1 with its inhibitor | | 分子名称: | Beta-secretase 1, METHYL (2S)-1-[(2R,5S,8S,12S,13S)-2,13-DIBENZYL-12-HYDROXY-3,5-DIMETHYL-8-(2-METHYLPROPYL)-15-(3-[(METHYLSULFONYL)AMINO]-5-{[(1R)-1-PHENYLETHYL]CARBAMOYL}PHENYL)-4,7,10,15-TETRAOXO-3,6,9,14-TETRAAZAPENTADECAN-1-OYL]PYRROLIDINE-2-CARBOXYLATE | | 著者 | Xu, Y.C, Chen, W.Y, Li, L, Chen, T.T. | | 登録日 | 2012-02-23 | | 公開日 | 2013-01-16 | | 最終更新日 | 2021-09-15 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases
J.Med.Chem., 55, 2012
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5OI9
 | | Trichoplax adhaerens STIL N-terminal domain | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Putative uncharacterized protein | | 著者 | van Breugel, M. | | 登録日 | 2017-07-18 | | 公開日 | 2018-04-18 | | 最終更新日 | 2018-05-09 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
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5OI7
 | | Human CEP85 - coiled coil domain 4 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal protein of 85 kDa | | 著者 | van Breugel, M. | | 登録日 | 2017-07-18 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
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5OID
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