5LNT
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![BU of 5lnt by Molmil](/molmil-images/mine/5lnt) | Crystal structure of Arabidopsis thaliana Pdx1K166R-preI320 complex | 分子名称: | PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.1, [(~{E},4~{S})-4-azanyl-3-oxidanylidene-pent-1-enyl] dihydrogen phosphate | 著者 | Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. | 登録日 | 2016-08-06 | 公開日 | 2017-01-18 | 最終更新日 | 2017-02-22 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
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5LNV
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![BU of 5lnv by Molmil](/molmil-images/mine/5lnv) | Crystal structure of Arabidopsis thaliana Pdx1-I320 complex from multiple crystals | 分子名称: | (4~{S})-4-azanyl-5-oxidanyl-pent-1-en-3-one, PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... | 著者 | Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. | 登録日 | 2016-08-06 | 公開日 | 2017-01-18 | 最終更新日 | 2018-09-19 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
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5LNR
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![BU of 5lnr by Molmil](/molmil-images/mine/5lnr) | Crystal structure of Arabidopsis thaliana Pdx1-PLP complex | 分子名称: | GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal 5'-phosphate synthase subunit PDX1.3 | 著者 | Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. | 登録日 | 2016-08-06 | 公開日 | 2017-01-18 | 最終更新日 | 2017-02-22 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
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5LNW
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![BU of 5lnw by Molmil](/molmil-images/mine/5lnw) | Crystal structure of Arabidopsis thaliana Pdx1-I320-G3P complex | 分子名称: | 5-O-phosphono-beta-D-ribofuranose, GLYCEROL, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... | 著者 | Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. | 登録日 | 2016-08-06 | 公開日 | 2017-01-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
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1FPB
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![BU of 1fpb by Molmil](/molmil-images/mine/1fpb) | CRYSTAL STRUCTURE OF THE NEUTRAL FORM OF FRUCTOSE 1,6-BISPHOSPHATASE COMPLEXED WITH REGULATORY INHIBITOR FRUCTOSE 2,6-BISPHOSPHATE AT 2.6-ANGSTROMS RESOLUTION | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, FRUCTOSE 1,6-BISPHOSPHATASE | 著者 | Liang, J.Y, Huang, S, Zhang, Y, Ke, H, Lipscomb, W.N. | 登録日 | 1992-02-03 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of the neutral form of fructose 1,6-bisphosphatase complexed with regulatory inhibitor fructose 2,6-bisphosphate at 2.6-A resolution. Proc.Natl.Acad.Sci.USA, 89, 1992
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7FIN
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![BU of 7fin by Molmil](/molmil-images/mine/7fin) | Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GIPR-Gs complex | 分子名称: | CHOLESTEROL, GAMMA-L-GLUTAMIC ACID, Gastric inhibitory polypeptide receptor,human glucose-dependent insulinotropic polypeptide receptor, ... | 著者 | Zhao, F.h, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-07-31 | 公開日 | 2022-02-23 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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7FIY
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![BU of 7fiy by Molmil](/molmil-images/mine/7fiy) | Cryo-EM structure of the tirzepatide-bound human GIPR-Gs complex | 分子名称: | CHOLESTEROL, Gastric inhibitory polypeptide receptor,Gastric inhibitory polypeptide receptor,human glucose-dependent insulinotropic polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-08-01 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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7FIM
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![BU of 7fim by Molmil](/molmil-images/mine/7fim) | Cryo-EM structure of the tirzepatide (LY3298176)-bound human GLP-1R-Gs complex | 分子名称: | Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,human glucagon like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-07-31 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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6PWW
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![BU of 6pww by Molmil](/molmil-images/mine/6pww) | Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | 登録日 | 2019-07-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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6PWC
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![BU of 6pwc by Molmil](/molmil-images/mine/6pwc) | A complex structure of arrestin-2 bound to neurotensin receptor 1 | 分子名称: | Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ... | 著者 | Yin, W, Li, Z, Jin, M, Yin, Y.-L, de Waal, P.W, Pal, K, Gao, X, He, Y, Gao, J, Wang, X, Zhang, Y, Zhou, H, Melcher, K, Jiang, Y, Cong, Y, Zhou, X.E, Yu, X, Xu, H.E. | 登録日 | 2019-07-22 | 公開日 | 2019-12-04 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | A complex structure of arrestin-2 bound to a G protein-coupled receptor. Cell Res., 29, 2019
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6PWX
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![BU of 6pwx by Molmil](/molmil-images/mine/6pwx) | Cryo-EM structure of RbBP5 bound to the nucleosome | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | 登録日 | 2019-07-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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6PWV
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![BU of 6pwv by Molmil](/molmil-images/mine/6pwv) | Cryo-EM structure of MLL1 core complex bound to the nucleosome | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | 登録日 | 2019-07-23 | 公開日 | 2019-12-18 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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3OS5
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![BU of 3os5 by Molmil](/molmil-images/mine/3os5) | SET7/9-Dnmt1 K142me1 complex | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Dnmt1, ... | 著者 | Esteve, P.-O, Chang, Y, Samaranayake, M, Upadhyay, A.K, Horton, J.R, Feehery, G.R, Cheng, X, Pradhan, S. | 登録日 | 2010-09-08 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat.Struct.Mol.Biol., 18, 2011
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7XLZ
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![BU of 7xlz by Molmil](/molmil-images/mine/7xlz) | |
7O6E
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![BU of 7o6e by Molmil](/molmil-images/mine/7o6e) | 2.12 A cryo-EM structure of Mycobacterium tuberculosis Ferritin | 分子名称: | Ferritin BfrB | 著者 | Gijsbers, A, Zhang, Y, Gao, Y, Peters, P.J, Ravelli, R.B.G. | 登録日 | 2021-04-10 | 公開日 | 2021-05-19 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Mycobacterium tuberculosis ferritin: a suitable workhorse protein for cryo-EM development. Acta Crystallogr D Struct Biol, 77, 2021
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6EDR
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![BU of 6edr by Molmil](/molmil-images/mine/6edr) | Crystal Structure of Human CD38 in Complex with 4'-Thioribose NAD+ | 分子名称: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)thiolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | 著者 | Dai, Z, Zhang, X.N, Nasertorabi, F, Cheng, Q, Pei, H, Louie, S.G, Stevens, C.R, Zhang, Y. | 登録日 | 2018-08-10 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Facile chemoenzymatic synthesis of a novel stable mimic of NAD. Chem Sci, 9, 2018
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6PB0
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![BU of 6pb0 by Molmil](/molmil-images/mine/6pb0) | Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 1 receptor in complex with Gs protein and Nb35 | 分子名称: | CHOLESTEROL, Corticotropin-releasing factor receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. | 登録日 | 2019-06-12 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
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7BV2
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![BU of 7bv2 by Molmil](/molmil-images/mine/7bv2) | The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP) | 分子名称: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. | 登録日 | 2020-04-09 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
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7BV1
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![BU of 7bv1 by Molmil](/molmil-images/mine/7bv1) | Cryo-EM structure of the apo nsp12-nsp7-nsp8 complex | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. | 登録日 | 2020-04-09 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
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6PB1
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![BU of 6pb1 by Molmil](/molmil-images/mine/6pb1) | Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 | 分子名称: | CHOLESTEROL, Corticotropin-releasing factor receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. | 登録日 | 2019-06-12 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
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1GN6
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![BU of 1gn6 by Molmil](/molmil-images/mine/1gn6) | G152A mutant of Mycobacterium tuberculosis iron-superoxide dismutase. | 分子名称: | FE (III) ION, SUPEROXIDE DISMUTASE | 著者 | Bunting, K.A, Cooper, J.B, Saward, S, Erskine, P.T, Badasso, M.O, Wood, S.P, Zhang, Y, Young, D.B. | 登録日 | 2001-10-03 | 公開日 | 2001-10-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | X-Ray Structure Analysis of an Engineered Fe-Superoxide Dismutase Gly-Ala Mutant with Significantly Reduced Stability to Denaturant FEBS Lett., 387, 1996
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6AZ3
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![BU of 6az3 by Molmil](/molmil-images/mine/6az3) | Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin | 分子名称: | 60S ribosomal protein L10, putative, 60S ribosomal protein L11 (L5, ... | 著者 | Shalev-Benami, M, Zhang, Y, Rozenberg, H, Nobe, Y, Taoka, M, Matzov, D, Zimmerman, E, Bashan, A, Isobe, T, Jaffe, C.L, Yonath, A, Skiniotis, G. | 登録日 | 2017-09-09 | 公開日 | 2017-12-06 | 最終更新日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin. Nat Commun, 8, 2017
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7VAB
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![BU of 7vab by Molmil](/molmil-images/mine/7vab) | Cryo-EM structure of the non-acylated tirzepatide (LY3298176)-bound human GIPR-Gs complex | 分子名称: | CHOLESTEROL, Gastric inhibitory polypeptide receptor,Gastric inhibitory polypeptide receptor,Gastric inhibitory polypeptide receptor,human glucose-dependent insulinotropic polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-08-28 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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7VBI
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![BU of 7vbi by Molmil](/molmil-images/mine/7vbi) | Cryo-EM structure of the non-acylated tirzepatide (LY3298176)-bound human GLP-1R-Gs complex | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-08-31 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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3O71
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![BU of 3o71 by Molmil](/molmil-images/mine/3o71) | Crystal structure of ERK2/DCC peptide complex | 分子名称: | Mitogen-activated protein kinase 1, Peptide of Deleted in Colorectal Cancer, THIOCYANATE ION | 著者 | Ma, W.F, Shang, Y, Wei, Z.Y, Wen, W.Y, Wang, W.N, Zhang, M.J. | 登録日 | 2010-07-30 | 公開日 | 2011-06-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase Structure, 18, 2010
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