4Q2V
 
 | | Crystal Structure of Ricin A chain complexed with Baicalin inhibitor | | 分子名称: | 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, Ricin | | 著者 | Deng, X, Li, X, Dong, J, Chen, Y. | | 登録日 | 2014-04-10 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | Baicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.
J.Biol.Chem., 290, 2015
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3TEF
 | | Crystal Structure of the Periplasmic Catecholate-Siderophore Binding Protein VctP from Vibrio Cholerae | | 分子名称: | Iron(III) ABC transporter, periplasmic iron-compound-binding protein | | 著者 | Liu, X, Wang, Z, Liu, S, Li, N, Chen, Y, Zhu, C, Zhu, D, Wei, T, Huang, Y, Xu, S, Gu, L. | | 登録日 | 2011-08-13 | | 公開日 | 2012-08-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Crystal structure of periplasmic catecholate-siderophore binding protein VctP from Vibrio cholerae at 1.7 A resolution
Febs Lett., 586, 2012
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5WSU
 | | Crystal structure of Myosin VIIa IQ5-SAH in complex with apo-CaM | | 分子名称: | Calmodulin, Unconventional myosin-VIIa | | 著者 | Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M. | | 登録日 | 2016-12-08 | | 公開日 | 2017-06-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension
Structure, 25, 2017
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5EKI
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5WST
 | | Crystal structure of Myo7a SAH | | 分子名称: | Unconventional myosin-VIIa | | 著者 | Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M. | | 登録日 | 2016-12-08 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension
Structure, 25, 2017
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5WSV
 | | Crystal structure of Myosin VIIa IQ5 in complex with Ca2+-CaM | | 分子名称: | CALCIUM ION, Calmodulin, SULFATE ION, ... | | 著者 | Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M. | | 登録日 | 2016-12-08 | | 公開日 | 2017-06-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension
Structure, 25, 2017
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4PAS
 | | Heterodimeric coiled-coil structure of human GABA(B) receptor | | 分子名称: | Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2 | | 著者 | Burmakina, S, Geng, Y, Chen, Y, Fan, Q.R. | | 登録日 | 2014-04-10 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Heterodimeric coiled-coil interactions of human GABAB receptor.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5FNO
 | | Manganese Lipoxygenase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MANGANESE (II) ION, ... | | 著者 | Wennman, A, Karkehabadi, S, Oliw, E.H, Chen, Y. | | 登録日 | 2015-11-16 | | 公開日 | 2016-01-27 | | 最終更新日 | 2025-04-09 | | 実験手法 | X-RAY DIFFRACTION (2.038 Å) | | 主引用文献 | Crystal Structure of Manganese Lipoxygenase of the Rice Blast Fungus Magnaporthe Oryzae
J.Biol.Chem., 291, 2016
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5GOR
 | | Crystal structure of alkaline invertase InvA from Anabaena sp. PCC 7120 | | 分子名称: | Alkaline Invertase, GLYCEROL, SULFATE ION | | 著者 | Xie, J, Cai, K, Hu, H.X, Jiang, Y.L, Yang, F, Hu, P.F, Chen, Y, Zhou, C.Z. | | 登録日 | 2016-07-28 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.673 Å) | | 主引用文献 | Structural Analysis of the Catalytic Mechanism and Substrate Specificity of Anabaena Alkaline Invertase InvA Reveals a Novel Glucosidase
J. Biol. Chem., 291, 2016
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8DZB
 | | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor 11 | | 分子名称: | 3C-like proteinase nsp5, GLYCEROL, benzyl {(3S)-1-[(2S)-1-({(2S,3R)-4-(cyclopropylamino)-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-5-oxopyrrolidin-3-yl}carbamate | | 著者 | Sacco, M, Chen, Y. | | 登録日 | 2022-08-06 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Development of the Safe and Broad-Spectrum Aldehyde and Ketoamide Mpro inhibitors Derived from the Constrained alpha , gamma-AA Peptide Scaffold.
Chemistry, 29, 2023
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8DZC
 | | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor 17 | | 分子名称: | (3,5-difluorophenyl)methyl {(3S)-1-[(2S)-1-({(2S,3R)-4-(cyclopropylamino)-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-6-oxopiperidin-3-yl}carbamate, 3C-like proteinase nsp5, GLYCEROL | | 著者 | Sacco, M, Chen, Y. | | 登録日 | 2022-08-06 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Development of the Safe and Broad-Spectrum Aldehyde and Ketoamide Mpro inhibitors Derived from the Constrained alpha , gamma-AA Peptide Scaffold.
Chemistry, 29, 2023
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2LVO
 | | Structure of the gp78CUE domain bound to monubiquitin | | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | | 登録日 | 2012-07-09 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
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3QFO
 | | Crystal structure of Streptococcal asymmetric Ap4A hydrolase and phosphodiesterase Spr1479/SapH im complex with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, FE (III) ION, MANGANESE (II) ION, ... | | 著者 | Jiang, Y.L, Zhang, J.W, Yu, W.L, Cheng, W, Zhang, C.C, Zhou, C.Z, Chen, Y. | | 登録日 | 2011-01-22 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
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8Y58
 | | Crystal structure of TRIM21 PRYSPRY (D355A) in complex with acepromazine. | | 分子名称: | 1-[10-(3-DIMETHYLAMINO-PROPYL)-10H-PHENOTHIAZIN-2-YL]-ETHANONE, E3 ubiquitin-protein ligase TRIM21, FORMIC ACID | | 著者 | Lu, P, Cheng, Y, Xue, L, Ren, X, Huang, N, Han, T. | | 登録日 | 2024-01-31 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders.
Cell, 187, 2024
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8Y59
 | | Crystal structure of TRIM21 PRYSPRY (D355A) in complex with (S)-hydroxyl-acepromazine. | | 分子名称: | (1~{S})-1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanol, E3 ubiquitin-protein ligase TRIM21 | | 著者 | Lu, P, Cheng, Y, Xue, L, Ren, X, Huang, N, Han, T. | | 登録日 | 2024-01-31 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders.
Cell, 187, 2024
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8Y5B
 | | Crystal structure of TRIM21 PRYSPRY (D355A) in complex with (R)-hydroxyl-acepromazine. | | 分子名称: | (1~{R})-1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanol, E3 ubiquitin-protein ligase TRIM21 | | 著者 | Lu, P, Cheng, Y, Xue, L, Ren, X, Huang, N, Han, T. | | 登録日 | 2024-01-31 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders.
Cell, 187, 2024
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5A6U
 | | Native mammalian ribosome-bound Sec61 protein-conducting channel in the 'non-inserting' state | | 分子名称: | SEC61A, SEC61B, SEC61G | | 著者 | Pfeffer, S, Burbaum, L, Unverdorben, P, Pech, M, Chen, Y, Zimmermann, R, Beckmann, R, Foerster, F. | | 登録日 | 2015-07-01 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structure of the Native Sec61 Protein-Conducting Channel.
Nat.Commun., 6, 2015
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3QFN
 | | Crystal structure of Streptococcal asymmetric Ap4A hydrolase and phosphodiesterase Spr1479/SapH in complex with inorganic phosphate | | 分子名称: | FE (III) ION, MANGANESE (II) ION, PHOSPHATE ION, ... | | 著者 | Jiang, Y.L, Zhang, J.W, Yu, W.L, Cheng, W, Zhang, C.C, Zhou, C.Z, Chen, Y. | | 登録日 | 2011-01-22 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
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4RM0
 | | Crystal structure of Norovirus OIF P domain in complex with Lewis a trisaccharide | | 分子名称: | Capsid protein, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z. | | 登録日 | 2014-10-18 | | 公開日 | 2015-06-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
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3QFM
 | | Crystal structure of Streptococcal asymmetric Ap4A hydrolase and phosphodiesterase Spr1479/SapH | | 分子名称: | FE (III) ION, MANGANESE (II) ION, Putative uncharacterized protein | | 著者 | Jiang, Y.L, Zhang, J.W, Yu, W.L, Cheng, W, Zhang, C.C, Zhou, C.Z, Chen, Y. | | 登録日 | 2011-01-22 | | 公開日 | 2011-08-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
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2LVQ
 | | gp78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin | | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | | 登録日 | 2012-07-09 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
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4RLZ
 | | Crystal structure of Norovirus OIF P domain | | 分子名称: | Capsid protein, GLYCEROL | | 著者 | Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z. | | 登録日 | 2014-10-18 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
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2KGP
 | | Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone) | | 分子名称: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, RNA (25-MER) | | 著者 | Zheng, S, Chen, Y, Donahue, C.P, Wolfe, M.S, Varani, G. | | 登録日 | 2009-03-13 | | 公開日 | 2009-06-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone).
Chem.Biol., 16, 2009
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2LVP
 | | gp78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin | | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | | 登録日 | 2012-07-09 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
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5DEM
 | | Structure of Pseudomonas aeruginosa LpxA | | 分子名称: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, PHOSPHATE ION | | 著者 | Smith, E.W, Chen, Y. | | 登録日 | 2015-08-25 | | 公開日 | 2015-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity.
Biochemistry, 54, 2015
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