8Y58
Crystal structure of TRIM21 PRYSPRY (D355A) in complex with acepromazine.
Summary for 8Y58
Entry DOI | 10.2210/pdb8y58/pdb |
Related | 8Y59 8Y5B |
Descriptor | E3 ubiquitin-protein ligase TRIM21, 1-[10-(3-DIMETHYLAMINO-PROPYL)-10H-PHENOTHIAZIN-2-YL]-ETHANONE, FORMIC ACID, ... (4 entities in total) |
Functional Keywords | trim21, pryspry, acepromazine, ligase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 22061.76 |
Authors | |
Primary citation | Lu, P.,Cheng, Y.,Xue, L.,Ren, X.,Chen, C.,Li, J.,Wu, Q.,Sun, S.,Hou, J.,Jia, W.,Li, C.,Qi, X.,Huang, N.,Han, T. Selective degradation of multimeric proteins via chemically induced proximity to TRIM21. To be published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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