Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8Y58

Crystal structure of TRIM21 PRYSPRY (D355A) in complex with acepromazine.

Summary for 8Y58
Entry DOI10.2210/pdb8y58/pdb
Related8Y59 8Y5B
DescriptorE3 ubiquitin-protein ligase TRIM21, 1-[10-(3-DIMETHYLAMINO-PROPYL)-10H-PHENOTHIAZIN-2-YL]-ETHANONE, FORMIC ACID, ... (4 entities in total)
Functional Keywordstrim21, pryspry, acepromazine, ligase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight22061.76
Authors
Lu, P.,Cheng, Y.,Xue, L.,Ren, X.,Huang, N.,Han, T. (deposition date: 2024-01-31, release date: 2024-10-09)
Primary citationLu, P.,Cheng, Y.,Xue, L.,Ren, X.,Chen, C.,Li, J.,Wu, Q.,Sun, S.,Hou, J.,Jia, W.,Li, C.,Qi, X.,Huang, N.,Han, T.
Selective degradation of multimeric proteins via chemically induced proximity to TRIM21.
To be published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon