4XMP
| Crystal structure of broadly and potently neutralizing antibody VRC08 in complex with HIV-1 clade A strain Q842.d12 gp120 | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2015-01-15 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7831 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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4XVS
| Crystal structure of HIV-1 donor 45 d45-01dG5 coreE gp120 with antibody 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 Light chain, Donor 45 01dG5 coreE gp120, ... | 著者 | Joyce, M.G, Mascola, J.R, Kwong, P.D. | 登録日 | 2015-01-27 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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4XNZ
| Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2015-01-16 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.389 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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4XNY
| Crystal structure of broadly and potently neutralizing antibody VRC08C in complex with HIV-1 clade A strain Q842.d12 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC08C, ... | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2015-01-16 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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4XVT
| Crystal structure of HIV-1 93TH057 coreE gp120 with antibody 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) Light chain, ENVELOPE GLYCOPROTEIN GP120 OF HIV-1 CLADE A/E, ... | 著者 | Joyce, M.G, Mascola, J.R, Kwong, P.D. | 登録日 | 2015-01-28 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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4GEH
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6JWP
| crystal structure of EGOC | 分子名称: | Ego2, GTP-binding protein GTR1, GTP-binding protein GTR2, ... | 著者 | Zhang, T, Ding, J. | 登録日 | 2019-04-21 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases. Sci Adv, 5, 2019
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4YNL
| Crystal structure of the hood domain of Anabaena HetR in complex with the hexapeptide ERGSGR derived from PatS | 分子名称: | Heterocyst differentiation control protein, Heterocyst inhibition-signaling peptide | 著者 | Hu, H.X, Jiang, Y.L, Zhao, M.X, Zhang, C.C, Chen, Y, Zhou, C.Z. | 登録日 | 2015-03-10 | 公開日 | 2015-12-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into HetR-PatS interaction involved in cyanobacterial pattern formation Sci Rep, 5, 2015
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4YRV
| Crystal structure of Anabaena transcription factor HetR complexed with 21-bp DNA from hetP promoter | 分子名称: | CALCIUM ION, DNA (5'-D(P*AP*TP*GP*AP*GP*GP*GP*GP*TP*TP*AP*GP*AP*CP*CP*CP*CP*TP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*AP*GP*GP*GP*GP*TP*CP*TP*AP*AP*CP*CP*CP*CP*TP*CP*AP*T)-3'), ... | 著者 | Hu, H.X, Jiang, Y.L, Zhao, M.X, Zhang, C.C, Chen, Y, Zhou, C.Z. | 登録日 | 2015-03-16 | 公開日 | 2015-12-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into HetR-PatS interaction involved in cyanobacterial pattern formation Sci Rep, 5, 2015
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4WIV
| Crystal Structure of the first bromodomain of human BRD4 in complex with a novel inhibitor UMB32 (N-TERT-BUTYL-2-[4-(3,5-DIMETHYL-1,2-OXAZOL-4-YL) PHENYL]IMIDAZO[1,2-A]PYRAZIN-3-AMINE) | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, GLYCEROL, ... | 著者 | Xu, X, Blacklow, S. | 登録日 | 2014-09-26 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Biased multicomponent reactions to develop novel bromodomain inhibitors. J.Med.Chem., 57, 2014
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4NW7
| PDE4 catalytic domain | 分子名称: | (4-{[4-(3-chlorophenyl)-6-cyclopropyl-1,3,5-triazin-2-yl]amino}phenyl)acetic acid, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | 著者 | Fox III, D, Edwards, T.E. | 登録日 | 2013-12-05 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Discovery of triazines as selective PDE4B versus PDE4D inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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4OCS
| Crystal structure of human Fab CAP256-VRC26.10, a potent V1V2-directed HIV-1 neutralizing antibody | 分子名称: | CAP256-VRC26.10 heavy chain, CAP256-VRC26.10 light chain | 著者 | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | 登録日 | 2014-01-09 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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4OCW
| Crystal structure of human Fab CAP256-VRC26.06, a potent V1V2-directed HIV-1 neutralizing antibody | 分子名称: | CAP256-VRC26.06 heavy chain, CAP256-VRC26.06 light chain | 著者 | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | 登録日 | 2014-01-09 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | 主引用文献 | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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4Z8M
| Crystal structure of the MAVS-TRAF6 complex | 分子名称: | Peptide from Mitochondrial antiviral-signaling protein, TNF receptor-associated factor 6 | 著者 | Shi, Z.B, Zhou, Z. | 登録日 | 2015-04-09 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural Insights into Mitochondrial Antiviral Signaling Protein (MAVS)-Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Signaling J.Biol.Chem., 290, 2015
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4FZF
| Crystal structure of MST4-MO25 complex with DKI | 分子名称: | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, Calcium-binding protein 39, Serine/threonine-protein kinase MST4 | 著者 | Shi, Z.B, Zhou, Z.C. | 登録日 | 2012-07-06 | 公開日 | 2013-03-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | 主引用文献 | Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism Structure, 21, 2013
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4U68
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7LLQ
| Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity | 分子名称: | 1-benzyl-4-methoxybenzene, 1-{4-oxo-4-[(2S)-pyrrolidin-2-yl]butanoyl}-L-proline, Leukotriene A-4 hydrolase, ... | 著者 | Lee, K.H, Lee, S.H, Shim, Y.M, Paige, M, Noble, S.M. | 登録日 | 2021-02-04 | 公開日 | 2022-06-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation. Sci Rep, 12, 2022
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4FZD
| Crystal structure of MST4-MO25 complex with WSF motif | 分子名称: | C-terminal peptide from Serine/threonine-protein kinase MST4, Calcium-binding protein 39, GLYCEROL, ... | 著者 | Shi, Z.B, Zhou, Z.C. | 登録日 | 2012-07-06 | 公開日 | 2013-03-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism Structure, 21, 2013
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6L0X
| The First Tudor Domain of PHF20L1 | 分子名称: | CITRIC ACID, GLYCEROL, PHD finger protein 20-like protein 1 | 著者 | Lv, M.Q, Gao, J. | 登録日 | 2019-09-27 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1. J Phys Chem Lett, 11, 2020
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6L1P
| Crystal structure of PHF20L1 in complex with Hit 1 | 分子名称: | 4-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)phenol, GLYCEROL, PHD finger protein 20-like protein 1, ... | 著者 | Lv, M.Q, Gao, J. | 登録日 | 2019-09-29 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.231 Å) | 主引用文献 | Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1. J Phys Chem Lett, 11, 2020
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6KPP
| BNC105 in complex with tubulin | 分子名称: | (6-methoxy-2-methyl-7-oxidanyl-1-benzofuran-3-yl)-(3,4,5-trimethoxyphenyl)methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, T, Wu, C, Pu, D. | 登録日 | 2019-08-15 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.74524117 Å) | 主引用文献 | Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design. Biochem.Biophys.Res.Commun., 2020
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6L1C
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6L1I
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4YJN
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4FZA
| Crystal structure of MST4-MO25 complex | 分子名称: | Calcium-binding protein 39, GLYCEROL, Serine/threonine-protein kinase MST4 | 著者 | Shi, Z.B, Zhou, Z.C. | 登録日 | 2012-07-06 | 公開日 | 2013-03-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism Structure, 21, 2013
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