7LLQ

Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity

Summary for 7LLQ

• Entry DOI: 10.2210/pdb7llq/pdb
• Descriptor: Leukotriene A-4 hydrolase, ZINC ION, 1-benzyl-4-methoxybenzene, ... (5 entities in total)
• Functional Keywords: leukotriene a4 hydrolase, 4mdm, aminipeptidase, activator, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 209687.84

Authors

Lee, K.H.,Lee, S.H.,Shim, Y.M.,Paige, M.,Noble, S.M. (deposition date: 2021-02-04, release date: 2022-06-22, Last modification date: 2023-10-18)

• Primary citation: Lee, K.H.,Ali, N.F.,Lee, S.H.,Zhang, Z.,Burdick, M.,Beaulac, Z.J.,Petruncio, G.,Li, L.,Xiang, J.,Chung, E.M.,Foreman, K.W.,Noble, S.M.,Shim, Y.M.,Paige, M.; Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation.; Sci Rep, 12:9443-9443, 2022; PubMed: 35676292; DOI: 10.1038/s41598-022-13238-6

Experimental method

X-RAY DIFFRACTION (2.85 Å)