7LLQ
Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity
Summary for 7LLQ
Entry DOI | 10.2210/pdb7llq/pdb |
Descriptor | Leukotriene A-4 hydrolase, ZINC ION, 1-benzyl-4-methoxybenzene, ... (5 entities in total) |
Functional Keywords | leukotriene a4 hydrolase, 4mdm, aminipeptidase, activator, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 209687.84 |
Authors | Lee, K.H.,Lee, S.H.,Shim, Y.M.,Paige, M.,Noble, S.M. (deposition date: 2021-02-04, release date: 2022-06-22, Last modification date: 2023-10-18) |
Primary citation | Lee, K.H.,Ali, N.F.,Lee, S.H.,Zhang, Z.,Burdick, M.,Beaulac, Z.J.,Petruncio, G.,Li, L.,Xiang, J.,Chung, E.M.,Foreman, K.W.,Noble, S.M.,Shim, Y.M.,Paige, M. Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation. Sci Rep, 12:9443-9443, 2022 Cited by PubMed: 35676292DOI: 10.1038/s41598-022-13238-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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