2N1T
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![BU of 2n1t by Molmil](/molmil-images/mine/2n1t) | Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution | 分子名称: | Synaptosomal-associated protein 25, Synaptotagmin-1, Syntaxin-1A, ... | 著者 | Brewer, K, Bacaj, T, Cavalli, A, Camilloni, C, Swarbrick, J, Liu, J, Zhou, A, Zhou, P, Barlow, N, Xu, J, Seven, A, Prinslow, E, Voleti, R, Haussinger, D, Bonvin, A, Tomchick, D, Vendruscolo, M, Graham, B, Sudhof, T, Rizo, J. | 登録日 | 2015-04-21 | 公開日 | 2015-06-03 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution. Nat.Struct.Mol.Biol., 22, 2015
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4ON3
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![BU of 4on3 by Molmil](/molmil-images/mine/4on3) | Crystal structure of human sorting nexin 10 (SNX10) | 分子名称: | NITRATE ION, PENTAETHYLENE GLYCOL, SODIUM ION, ... | 著者 | Xu, T, Xu, J, Wang, Q, Liu, J. | 登録日 | 2014-01-28 | 公開日 | 2014-09-24 | 最終更新日 | 2014-12-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis. Proteins, 82, 2014
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3SWV
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![BU of 3swv by Molmil](/molmil-images/mine/3swv) | Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) from Homo sapiens (Human), Northeast Structural Genomics Consortium target id HR5562A | 分子名称: | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | 著者 | Seetharaman, J, Su, M, Forouhar, F, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-07-14 | 公開日 | 2011-08-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human), Northeast Structural Genomics Consortium target id HR5562A To be Published
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8GDX
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![BU of 8gdx by Molmil](/molmil-images/mine/8gdx) | |
8GE0
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![BU of 8ge0 by Molmil](/molmil-images/mine/8ge0) | |
3TJ0
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![BU of 3tj0 by Molmil](/molmil-images/mine/3tj0) | Crystal Structure of Influenza B Virus Nucleoprotein | 分子名称: | Nucleoprotein | 著者 | Ng, A.K.L, Zhang, H, Liu, J, Au, S.W.N, Wang, J, Shaw, P.C. | 登録日 | 2011-08-23 | 公開日 | 2012-06-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.233 Å) | 主引用文献 | Structural basis for RNA binding and homo-oligomer formation by influenza B virus nucleoprotein J.Virol., 86, 2012
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4PZG
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![BU of 4pzg by Molmil](/molmil-images/mine/4pzg) | Crystal structure of human sorting nexin 10 (SNX10) | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, NITRATE ION, Sorting nexin-10 | 著者 | Xu, T, Xu, J, Wang, Q, Liu, J. | 登録日 | 2014-03-30 | 公開日 | 2014-09-24 | 最終更新日 | 2014-12-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis. Proteins, 82, 2014
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6ATG
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![BU of 6atg by Molmil](/molmil-images/mine/6atg) | Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis | 分子名称: | Complement regulator-acquiring surface protein 2 (CRASP-2), HCG40889, isoform CRA_b, ... | 著者 | Liu, A, Yan, H, Wu, Y, Li, Y, Liu, J. | 登録日 | 2017-08-29 | 公開日 | 2018-09-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis To Be Published
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2OKA
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![BU of 2oka by Molmil](/molmil-images/mine/2oka) | Crystal structure of Q9HYQ7_PSEAE from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR82 | 分子名称: | Hypothetical protein | 著者 | Benach, J, Neely, H, Seetharaman, J, Chen, X.C, Fang, Y, Cunningham, K, Owens, L, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-01-16 | 公開日 | 2007-01-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of Q9HYQ7_PSEAE from Pseudomonas aeruginosa To be Published
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2O5A
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![BU of 2o5a by Molmil](/molmil-images/mine/2o5a) | Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21 | 分子名称: | BH1328 protein, MANGANESE (II) ION, SULFATE ION | 著者 | Benach, J, Su, M, Seetharaman, J, Ho, C.H, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-12-05 | 公開日 | 2006-12-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21 To be Published
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2OAS
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![BU of 2oas by Molmil](/molmil-images/mine/2oas) | Crystal Structure of 4-hydroxybutyrate coenzyme A transferase (AtoA) in complex with CoA from Shewanella oneidensis, Northeast Structural Genomics Target SoR119. | 分子名称: | 4-hydroxybutyrate coenzyme A transferase, COENZYME A | 著者 | Forouhar, F, Neely, H, Hussain, M, Benach, J, Seetharaman, J, Cunningham, K, Ma, L.C, Owen, L, Fang, Y, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-12-17 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of 4-hydroxybutyrate coenzyme A transferase (AtoA) from Shewanella oneidensis in complex with CoA, Northeast Structural Genomics Target SoR119. To be Published
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2OJL
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![BU of 2ojl by Molmil](/molmil-images/mine/2ojl) | Crystal structure of Q7WAF1_BORPA from Bordetella parapertussis. Northeast Structural Genomics target BpR68. | 分子名称: | Hypothetical protein | 著者 | Benach, J, Neely, H, Seetharaman, J, Wang, H, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-01-12 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Q7WAF1_BORPA from Bordetella parapertussis To be Published
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7C7Q
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![BU of 7c7q by Molmil](/molmil-images/mine/7c7q) | Cryo-EM structure of the baclofen/BHFF-bound human GABA(B) receptor in active state | 分子名称: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | 登録日 | 2020-05-26 | 公開日 | 2020-07-01 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM structures of inactive and active GABABreceptor. Cell Res., 30, 2020
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7C7S
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![BU of 7c7s by Molmil](/molmil-images/mine/7c7s) | Cryo-EM structure of the CGP54626-bound human GABA(B) receptor in inactive state. | 分子名称: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | 登録日 | 2020-05-26 | 公開日 | 2020-07-01 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of inactive and active GABABreceptor. Cell Res., 30, 2020
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7CKI
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![BU of 7cki by Molmil](/molmil-images/mine/7cki) | Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP | 分子名称: | (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Lyu, G, Fan, S, Jin, Y, Liu, J, Zou, S, Wu, G, Yang, Z. | 登録日 | 2020-07-17 | 公開日 | 2021-07-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP To Be Published
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2K5Q
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![BU of 2k5q by Molmil](/molmil-images/mine/2k5q) | NMR Solution structure of membrane associated protein from Bacillus cereus: Northeast Structural Genomics Consortium Target: BcR97A | 分子名称: | Hypothetical Membrane Associated Protein BcR97A | 著者 | Swapna, G, Wang, D, Owens, L, Xiao, R, Liu, J, Baran, M.C, Everett, J, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-06-30 | 公開日 | 2008-08-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution Structure of Membrane associated protein from Bacillus cereus: Northeast Structural Genomics Consortium Target: BcR97A To be Published
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2KAN
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![BU of 2kan by Molmil](/molmil-images/mine/2kan) | Solution NMR structure of ubiquitin-like domain of Arabidopsis thaliana protein At2g32350. Northeast Structural Genomics Consortium target AR3433A | 分子名称: | uncharacterized protein ar3433a | 著者 | Eletsky, A, Mills, J.L, Sukumaran, D, Hua, J, Shastry, R, Jiang, M, Ciccosanti, C, Xiao, R, Liu, J, Everret, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-11-11 | 公開日 | 2008-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of ubiquitin-like domain of Arabidopsis thaliana protein At2g32350. To be Published
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5XDZ
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![BU of 5xdz by Molmil](/molmil-images/mine/5xdz) | Crystal structure of zebrafish SNX25 PX domain | 分子名称: | CHLORIDE ION, Cellular trafficking protein, SODIUM ION | 著者 | Su, K, Zhang, Y, Xu, J, Liu, J. | 登録日 | 2017-03-30 | 公開日 | 2017-06-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the PX domain of SNX25 reveals a novel phospholipid recognition model by dimerization in the PX domain FEBS Lett., 591, 2017
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6A5W
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![BU of 6a5w by Molmil](/molmil-images/mine/6a5w) | FXR-LBD with HNC143 and SRC1 | 分子名称: | 2-[2-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-6-azaspiro[3.4]octan-6-yl]-1,3-benzothiazole-6-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1 | 著者 | Wang, N, Liu, J. | 登録日 | 2018-06-25 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
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3R02
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![BU of 3r02 by Molmil](/molmil-images/mine/3r02) | The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors | 分子名称: | 7-[(cis-4-aminocyclohexyl)amino]-5-bromo-1-benzofuran-2-carboxylic acid, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase pim-1 | 著者 | Xiang, Y, Hirth, B, Asmussen, G, Biemann, H.-P, Good, A, Fitzgerald, M, Gladysheva, T, Jancsics, K, Liu, J, Metz, M, Papoulis, A, Skerlj, R, Stepp, D.J, Wei, R.R. | 登録日 | 2011-03-07 | 公開日 | 2011-05-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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6A5Y
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![BU of 6a5y by Molmil](/molmil-images/mine/6a5y) | Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC143 and 9cRA and SRC1 | 分子名称: | (9cis)-retinoic acid, 2-[2-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-6-azaspiro[3.4]octan-6-yl]-1,3-benzothiazole-6-carboxylic acid, Bile acid receptor, ... | 著者 | Wang, N, Liu, J. | 登録日 | 2018-06-25 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
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6A5X
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![BU of 6a5x by Molmil](/molmil-images/mine/6a5x) | FXR-LBD with HNC180 and SRC1 | 分子名称: | 2-[(1R,5S)-9-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-3-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzothiazole-6-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1, ... | 著者 | Wang, N, Liu, J. | 登録日 | 2018-06-25 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
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6A5Z
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![BU of 6a5z by Molmil](/molmil-images/mine/6a5z) | Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC180 and 9cRA and SRC1 | 分子名称: | (9cis)-retinoic acid, 2-[(1R,5S)-9-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-3-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzothiazole-6-carboxylic acid, Bile acid receptor, ... | 著者 | Wang, N, Liu, J. | 登録日 | 2018-06-25 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
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6A60
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![BU of 6a60 by Molmil](/molmil-images/mine/6a60) | Crystal structure of human FXR/RXR-LBD heterodimer bound to GW4064 and 9cRA and SRC1 | 分子名称: | (9cis)-retinoic acid, 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid, Bile acid receptor, ... | 著者 | Wang, N, Liu, J. | 登録日 | 2018-06-25 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
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2NMU
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![BU of 2nmu by Molmil](/molmil-images/mine/2nmu) | Crystal structure of the hypothetical protein from Salmonella typhimurium LT2. Northeast Structural Genomics Consortium target StR127. | 分子名称: | Putative DNA-binding protein | 著者 | Kuzin, A.P, Abashidze, M, Seetharaman, J, Wang, H, Nwosu, C, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-10-23 | 公開日 | 2006-11-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the hypothetical protein from Salmonella typhimurium LT2. Northeast Structural Genomics Consortium target StR127. To be Published
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