6A5X

FXR-LBD with HNC180 and SRC1

Summary for 6A5X

• Entry DOI: 10.2210/pdb6a5x/pdb
• Related: 6A5W
• Descriptor: Bile acid receptor, Nuclear receptor coactivator 1, SULFATE ION, ... (5 entities in total)
• Functional Keywords: nuclear receptor, coactivator, agonist, complex, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 29336.20

Authors

Wang, N.,Liu, J. (deposition date: 2018-06-25, release date: 2018-10-10, Last modification date: 2024-03-27)

• Primary citation: Wang, N.,Zou, Q.,Xu, J.,Zhang, J.,Liu, J.; Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding; J. Biol. Chem., 293:18180-18191, 2018; PubMed: 30275017; DOI: 10.1074/jbc.RA118.004652

Experimental method

X-RAY DIFFRACTION (2.6 Å)