Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032052 | molecular_function | bile acid binding |
| A | 0038183 | biological_process | bile acid signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | ASN271 |
| A | LYS275 |
| A | SER279 |
| A | ALA280 |
| A | ASN354 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | GLN416 |
| A | PHE430 |
| A | ARG436 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | GLN267 |
| A | GLU268 |
| A | PRO266 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | LYS338 |
| A | THR378 |
| A | GLN379 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue 9R3 A 505 |
| Chain | Residue |
| A | ARG264 |
| A | THR270 |
| A | LEU287 |
| A | THR288 |
| A | MET328 |
| A | PHE329 |
| A | ARG331 |
| A | SER332 |
| A | ILE335 |
| A | SER342 |
| A | GLY343 |
| A | TYR369 |
| A | HIS447 |
| A | TRP454 |
| A | TRP469 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 801 |
| Chain | Residue |
| A | SER453 |
| A | VAL456 |
| A | ASN457 |
| B | TYR751 |
| B | LYS755 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 224 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"6HL1","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKC/PRKCZ","evidences":[{"source":"PubMed","id":"18668687","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"23546875","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Motif: {"description":"LXXLL motif 5"} |
6A5X
