1AV8
 
 | | RIBONUCLEOTIDE REDUCTASE R2 SUBUNIT FROM E. COLI | | 分子名称: | MU-OXO-DIIRON, RIBONUCLEOTIDE REDUCTASE R2 | | 著者 | Han, S, Arvai, A, Tainer, J.A. | | 登録日 | 1997-09-30 | | 公開日 | 1998-10-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography.
Biochemistry, 37, 1998
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8T4S
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7MWH
 | | Crystal structure of BAZ2A with DNA | | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ... | | 著者 | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2021-05-17 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal structure of the BAZ2B TAM domain.
Heliyon, 8, 2022
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3F1Z
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6OGK
 | | MeCP2 MBD in complex with DNA | | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*CP*TP*CP*CP*G)-3'), ... | | 著者 | Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | | 登録日 | 2019-04-02 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.
Biochim Biophys Acta Gene Regul Mech, 1862, 2019
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8SDV
 | | Crystal structure of PDC-3 Y221H beta-lactamase in complex with the boronic acid inhibitor S02030 | | 分子名称: | 1-{(2R)-2-(dihydroxyboranyl)-2-[(thiophen-2-ylacetyl)amino]ethyl}-1H-1,2,3-triazole-4-carboxylic acid, Beta-lactamase, DIMETHYL SULFOXIDE, ... | | 著者 | Kumar, V, van den Akker, F. | | 登録日 | 2023-04-07 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase.
Antimicrob.Agents Chemother., 67, 2023
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8SDR
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8SDN
 | | Crystal structure of PDC-3 Y221H beta-lactamase | | 分子名称: | Beta-lactamase, ISOPROPYL ALCOHOL | | 著者 | Kumar, V, van den Akker, F. | | 登録日 | 2023-04-07 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase.
Antimicrob.Agents Chemother., 67, 2023
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8SDL
 | | Crystal structure of PDC-3 beta-lactamase | | 分子名称: | Beta-lactamase, IMIDAZOLE, ISOPROPYL ALCOHOL | | 著者 | Kumar, V, van den Akker, F. | | 登録日 | 2023-04-07 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase.
Antimicrob.Agents Chemother., 67, 2023
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8SDT
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8SDS
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6WUS
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3DEE
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4YZC
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4YZ9
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4YZD
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2MP0
 | | Protein Phosphorylation upon a Fleeting Encounter | | 分子名称: | Glucose-specific phosphotransferase enzyme IIA component, PHOSPHITE ION, Phosphoenolpyruvate-protein phosphotransferase | | 著者 | Xing, Q, Yang, J, Huang, P, Zhang, W, Tang, C. | | 登録日 | 2014-05-08 | | 公開日 | 2014-08-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Visualizing an ultra-weak protein-protein interaction in phosphorylation signaling.
Angew.Chem.Int.Ed.Engl., 53, 2014
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3HW5
 | | crystal structure of avian influenza virus PA_N in complex with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Polymerase acidic protein | | 著者 | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Liang, S, Rao, Z. | | 登録日 | 2009-06-17 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center
J.Virol., 83, 2009
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4KJU
 | | Crystal structure of XIAP-Bir2 with a bound benzodiazepinone inhibitor. | | 分子名称: | E3 ubiquitin-protein ligase XIAP, N-{(3S)-5-(4-aminobenzoyl)-1-[(2-methoxynaphthalen-1-yl)methyl]-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl}-N~2~-methyl-L-alaninamide, ZINC ION | | 著者 | Lukacs, C.M, Janson, C.A. | | 登録日 | 2013-05-03 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Optimization of Benzodiazepinones as Selective Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain.
J.Med.Chem., 56, 2013
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4KJV
 | | Crystal structure of XIAP-Bir2 with a bound spirocyclic benzoxazepinone inhibitor. | | 分子名称: | 6-methoxy-5-({(3S)-3-[(N-methyl-L-alanyl)amino]-4-oxo-2',3,3',4,5',6'-hexahydro-5H-spiro[1,5-benzoxazepine-2,4'-pyran]-5-yl}methyl)naphthalene-2-carboxylic acid, E3 ubiquitin-protein ligase XIAP, ZINC ION | | 著者 | Lukacs, C.M, Janson, C.A. | | 登録日 | 2013-05-03 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Optimization of Benzodiazepinones as Selective Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain.
J.Med.Chem., 56, 2013
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2YU1
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8KG5
 | | Prefusion RSV F Bound to Lonafarnib and D25 Fab | | 分子名称: | 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, D25 heavy chain, D25 light chain, ... | | 著者 | Yang, Q, Xue, B, Liu, F, Peng, W, Chen, X. | | 登録日 | 2023-08-17 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Signal Transduct Target Ther, 9, 2024
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7QXP
 | | Proteasome-ZFAND5 Complex Z+B state | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhu, Y, Lu, Y. | | 登録日 | 2022-01-26 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Mol.Cell, 83, 2023
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7QXX
 | | Proteasome-ZFAND5 Complex Z+E state | | 分子名称: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | | 著者 | Zhu, Y, Lu, Y. | | 登録日 | 2022-01-27 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Mol.Cell, 83, 2023
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7QXU
 | | Proteasome-ZFAND5 Complex Z+C state | | 分子名称: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | | 著者 | Zhu, Y, Lu, Y. | | 登録日 | 2022-01-27 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Mol.Cell, 83, 2023
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