4WUY
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![BU of 4wuy by Molmil](/molmil-images/mine/4wuy) | Crystal Structure of Protein Lysine Methyltransferase SMYD2 in complex with LLY-507, a Cell-Active, Potent and Selective Inhibitor | 分子名称: | 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, GLYCEROL, N-lysine methyltransferase SMYD2, ... | 著者 | Nguyen, H, Allali-Hassani, A, Antonysamy, S, Chang, S, Chen, L.H, Curtis, C, Emtage, S, Fan, L, Gheyi, T, Li, F, Liu, S, Martin, J.R, Mendel, D, Olsen, J.B, Pelletier, L, Shatseva, T, Wu, S, Zhang, F.F, Arrowsmith, C.H, Brown, P.J, Campbell, R.M, Garcia, B.A, Barsyte-Lovejoy, D, Mader, M, Vedadi, M. | 登録日 | 2014-11-04 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J.Biol.Chem., 290, 2015
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7CBP
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![BU of 7cbp by Molmil](/molmil-images/mine/7cbp) | CryoEM structure of Zika virus with Fab at 4.1 Angstrom | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, Fab Heavy chain, ... | 著者 | Tyagi, A, Ahmed, T, Shi, J, Bhushan, S. | 登録日 | 2020-06-13 | 公開日 | 2020-07-08 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | A complex between the Zika virion and the Fab of a broadly cross-reactive neutralizing monoclonal antibody revealed by cryo-EM and single particle analysis at 4.1 angstrom resolution. J Struct Biol X, 4, 2020
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7X9B
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![BU of 7x9b by Molmil](/molmil-images/mine/7x9b) | Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Tang, T, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors. Sci Adv, 8, 2022
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7X9C
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![BU of 7x9c by Molmil](/molmil-images/mine/7x9c) | Cryo-EM structure of neuropeptide Y Y4 receptor in complex with PP and Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Tang, T, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors. Sci Adv, 8, 2022
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7X9A
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![BU of 7x9a by Molmil](/molmil-images/mine/7x9a) | Cryo-EM structure of neuropeptide Y Y1 receptor in complex with NPY and Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Tang, T, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors. Sci Adv, 8, 2022
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7WVY
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![BU of 7wvy by Molmil](/molmil-images/mine/7wvy) | Cryo-EM structure of the human formyl peptide receptor 2 in complex with Abeta42 and Gi2 | 分子名称: | Amyloid-beta A4 protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-02-11 | 公開日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7WVW
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![BU of 7wvw by Molmil](/molmil-images/mine/7wvw) | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMYFINILTL and Gi2 | 分子名称: | FME-TYR-PHE-ILE-ASN-ILE-LEU-THE-LEU, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-02-11 | 公開日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7WVU
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![BU of 7wvu by Molmil](/molmil-images/mine/7wvu) | Cryo-EM structure of the human formyl peptide receptor 1 in complex with fMLF and Gi1 | 分子名称: | FME-LEU-PHE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-02-11 | 公開日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7WVV
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![BU of 7wvv by Molmil](/molmil-images/mine/7wvv) | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMLFII and Gi2 | 分子名称: | FME-LEU-PHE-ILE-ILE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-02-11 | 公開日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7WVX
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![BU of 7wvx by Molmil](/molmil-images/mine/7wvx) | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fhumanin and Gi2 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | 著者 | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-02-11 | 公開日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7XBW
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![BU of 7xbw by Molmil](/molmil-images/mine/7xbw) | Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with Gi1 | 分子名称: | CHOLESTEROL, CX3C chemokine receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Lu, M, Zhao, W, Han, S, Zhu, Y, Wu, B, Zhao, Q. | 登録日 | 2022-03-22 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Activation of the human chemokine receptor CX3CR1 regulated by cholesterol. Sci Adv, 8, 2022
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7XBX
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![BU of 7xbx by Molmil](/molmil-images/mine/7xbx) | Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and Gi1 | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Lu, M, Zhao, W, Han, S, Zhu, Y, Wu, B, Zhao, Q. | 登録日 | 2022-03-22 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Activation of the human chemokine receptor CX3CR1 regulated by cholesterol. Sci Adv, 8, 2022
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8K90
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![BU of 8k90 by Molmil](/molmil-images/mine/8k90) | CryoEM structure of LonC protease open pentamer in presence of AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8V
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![BU of 8k8v by Molmil](/molmil-images/mine/8k8v) | CryoEM structure of LonC protease hepatmer, apo state | 分子名称: | PHOSPHATE ION, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8Z
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![BU of 8k8z by Molmil](/molmil-images/mine/8k8z) | CryoEM structure of LonC protease hexamer in presence of AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K92
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![BU of 8k92 by Molmil](/molmil-images/mine/8k92) | CryoEM structure of LonC S582A hexamer with Lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K95
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![BU of 8k95 by Molmil](/molmil-images/mine/8k95) | CryoEM structure of LonC protease open Hexamer, AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K91
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![BU of 8k91 by Molmil](/molmil-images/mine/8k91) | CryoEM structure of LonC S582A hepatmer with Lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K93
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![BU of 8k93 by Molmil](/molmil-images/mine/8k93) | CryoEM structure of LonC protease S582A open hexamer with lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8Y
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![BU of 8k8y by Molmil](/molmil-images/mine/8k8y) | CryoEM structure of LonC heptamer in presence of AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8W
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![BU of 8k8w by Molmil](/molmil-images/mine/8k8w) | CryoEM structure of LonC protease open hexamer, apo state | 分子名称: | endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K96
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![BU of 8k96 by Molmil](/molmil-images/mine/8k96) | CryoEM structure of LonC protease hepatmer with Bortezomib | 分子名称: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K97
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![BU of 8k97 by Molmil](/molmil-images/mine/8k97) | CryoEM structure of LonC protease hexamer with Bortezomib | 分子名称: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8X
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![BU of 8k8x by Molmil](/molmil-images/mine/8k8x) | CryoEM of LonC open pentamer, apo state | 分子名称: | endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K94
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![BU of 8k94 by Molmil](/molmil-images/mine/8k94) | CryoEM structure of LonC protease S582A open pentamer with lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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