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8YJG
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BU of 8yjg by Molmil
Crystal structure of the nucleotide-binding domain of Candida glabrata Hsp90
分子名称: ATP-dependent molecular chaperone HSC82
著者Tan, L, Li, X, Zhang, G, Chen, L, Im, Y.J.
登録日2024-03-01
公開日2025-03-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the nucleotide-binding domain of Candida glabrata Hsp90
To Be Published
3QRF
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BU of 3qrf by Molmil
Structure of a domain-swapped FOXP3 dimer
分子名称: Forkhead box protein P3, MAGNESIUM ION, Nuclear factor of activated T-cells, ...
著者Bandukwala, H.S, Wu, Y, Feurer, M, Chen, Y, Barbosa, B, Ghosh, S, Stroud, J.C, Benoist, C, Mathis, D, Rao, A, Chen, L.
登録日2011-02-17
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Immunity, 34, 2011
3R29
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BU of 3r29 by Molmil
Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2
分子名称: Nuclear receptor corepressor 2, Retinoic acid receptor RXR-alpha
著者Zhang, H, Chen, L, Chen, J, Jiang, H, Shen, X.
登録日2011-03-14
公開日2011-05-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for retinoic x receptor repression on the tetramer.
J.Biol.Chem., 286, 2011
3R2A
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BU of 3r2a by Molmil
Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and antagonist rhein
分子名称: 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, Nuclear receptor corepressor 2, Retinoic acid receptor RXR-alpha
著者Zhang, H, Chen, L, Chen, J, Jiang, H, Shen, X.
登録日2011-03-14
公開日2011-05-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for retinoic x receptor repression on the tetramer.
J.Biol.Chem., 286, 2011
8J6F
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BU of 8j6f by Molmil
Cryo-EM structure of the Tocilizumab Fab/IL-6R complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Tocilizumab Fab, IL6R-D2 peptide, ...
著者She, J, Chen, L.
登録日2023-04-25
公開日2024-03-27
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into IL-6 signaling inhibition by therapeutic antibodies.
Cell Rep, 43, 2024
8IOW
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BU of 8iow by Molmil
Cryo-EM structure of the sarilumab Fab/IL-6R complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Sarilumab Fab, Interleukin-6 receptor subunit alpha, ...
著者She, J, Chen, L, Wang, M.X.
登録日2023-03-13
公開日2024-03-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into IL-6 signaling inhibition by therapeutic antibodies.
Cell Rep, 43, 2024
7ULG
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BU of 7ulg by Molmil
recombinant alpha cobra toxin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, Alpha-cobratoxin
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-04
公開日2023-05-03
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structure of recombinant alpha cobra toxin at 1.57 Angstroms
To Be Published
7ULR
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BU of 7ulr by Molmil
recombinant kappa-bungarotoxin
分子名称: Kappa-bungarotoxin
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-05
公開日2023-05-03
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of recombinant kappa-bungarotoxin at 1.8 Angstroms resolution.
To Be Published
7ULS
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BU of 7uls by Molmil
Recombinant muscarinic toxin alpha
分子名称: GLYCEROL, Muscarinic toxin alpha
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-05
公開日2023-05-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献recombinant MTalpha at 1.8 Angstroms resolution
To Be Published
7ULB
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BU of 7ulb by Molmil
recombinant Mambalgin-1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Mambalgin-1
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-04
公開日2023-05-03
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure of recombinant mambalgin at 2.49 Angstroms resolution.
To Be Published
7ULQ
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BU of 7ulq by Molmil
Recombinant Hannalgesin
分子名称: ACETATE ION, GLYCEROL, Long neurotoxin OH-55, ...
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-05
公開日2023-05-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of recombinant Hannalgesin at 2.2 Angstroms resolution.
To Be Published
3OZJ
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BU of 3ozj by Molmil
Crystal structure of human retinoic X receptor alpha complexed with bigelovin and coactivator SRC-1
分子名称: (3aR,4S,4aR,7aR,8R,9aS)-4a,8-dimethyl-3-methylidene-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl acetate, Retinoic acid receptor RXR-alpha, SRC-1, ...
著者Zhang, H, Li, L, Chen, L, Hu, L, Shen, X.
登録日2010-09-25
公開日2011-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode
J.Mol.Biol., 407, 2011
3Q47
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BU of 3q47 by Molmil
Crystal structure of TPR domain of CHIP complexed with pseudophosphorylated Smad1 peptide
分子名称: STIP1 homology and U box-containing protein 1, Smad1 peptide
著者Wang, L, Chen, L, Wu, J.W.
登録日2010-12-23
公開日2011-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.705 Å)
主引用文献Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q49
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BU of 3q49 by Molmil
Crystal structure of the TPR domain of CHIP complexed with Hsp70-C peptide
分子名称: Hsp70-C peptide, STIP1 homology and U box-containing protein 1
著者Wang, L, Chen, L, Wu, J.W.
登録日2010-12-23
公開日2011-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.543 Å)
主引用文献Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q4A
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BU of 3q4a by Molmil
Crystal structure of the TPR domain of CHIP complexed with phosphorylated Smad1 peptide
分子名称: STIP1 homology and U box-containing protein 1, Smad1 peptide
著者Wang, L, Chen, L, Wu, J.W.
登録日2010-12-23
公開日2011-03-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.542 Å)
主引用文献Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3RTP
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BU of 3rtp by Molmil
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration
分子名称: Mitogen-activated protein kinase 10, N-[4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide
著者Bowers, S, Truong, A.P, Neitz, R.J, Hom, R.K, Sealy, J.M, Probst, G.D, Quincy, Q, Peterson, B, Chan, W, Galemmo Jr, R.A, Konradi, A.W, Sham, H.L, Pan, H, Lin, M, Yao, N, Artis, D.R, Zhang, H, Chen, L, Dryer, M, Samant, B, Zmolek, W, Wong, K, Lorentzen, C, Goldbach, E, Tonn, G, Quinn, K.P, Sauer, J, Wright, S, Powell, K, Ruslim, L, Ren, Z, Bard, F, Yednock, T.A, Griswold-Prenne, I.
登録日2011-05-03
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration.
Bioorg.Med.Chem.Lett., 21, 2011
3P8F
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BU of 3p8f by Molmil
Crystal Structure of MT-SP1 in complex with SFTI-1
分子名称: GLUTATHIONE, ST14 protein, Trypsin inhibitor 1
著者Yuan, C, Huang, M, Chen, L.
登録日2010-10-13
公開日2011-08-10
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1.
Bmc Struct.Biol., 11, 2011
3OV8
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BU of 3ov8 by Molmil
Crystal structure of AF1382 from Archaeoglobus fulgidus, High resolution
分子名称: ACETATE ION, CHLORIDE ION, Protein AF_1382
著者Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Hao, X, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2010-09-16
公開日2011-11-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8501 Å)
主引用文献Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal.
Acta Crystallogr.,Sect.D, 68, 2012
3PA2
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BU of 3pa2 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type Ley
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-10-18
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3PA1
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BU of 3pa1 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type A
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-10-18
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3Q6Q
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BU of 3q6q by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lea
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2011-01-03
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3PZ7
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BU of 3pz7 by Molmil
Crystal structure of Ccd1-DIX domain
分子名称: 1,2-ETHANEDIOL, Dixin
著者Liu, Y.T, Wang, J.W, Chen, L, Wu, J.W.
登録日2010-12-14
公開日2010-12-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.441 Å)
主引用文献Molecular basis of WNT Activation via the DIX-domain protein CCD1
To be Published
3Q3A
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BU of 3q3a by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type H2 (triglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q38
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Crystal structure of P domain from norwalk virus strain vietnam 026 in complex with HBGA type B (triglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q39
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Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type H2 (diglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011

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