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8U2Z
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BU of 8u2z by Molmil
TRPV1 in nanodisc bound with diC8-PIP2 in the dilated state
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, SODIUM ION, ...
著者Arnold, W.R, Julius, D, Cheng, Y.
登録日2023-09-06
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
3A31
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BU of 3a31 by Molmil
Crystal structure of putative threonyl-tRNA synthetase ThrRS-1 from Aeropyrum pernix (selenomethionine derivative)
分子名称: Probable threonyl-tRNA synthetase 1, SULFATE ION, ZINC ION
著者Shimizu, S, Juan, E.C.M, Miyashita, Y, Sato, Y, Hoque, M.M, Suzuki, K, Yogiashi, M, Tsunoda, M, Dock-Bregeon, A.-C, Moras, D, Sekiguchi, T, Takenaka, A.
登録日2009-06-07
公開日2009-10-27
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two complementary enzymes for threonylation of tRNA in crenarchaeota: crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain
J.Mol.Biol., 394, 2009
8T3M
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BU of 8t3m by Molmil
TRPV1 in nanodisc bound with 3 LPA molecules
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
著者Arnold, W.R, Julius, D, Cheng, Y.
登録日2023-06-07
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8TVF
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BU of 8tvf by Molmil
Langya henipavirus fusion protein in prefusion state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya henipavirus fusion protein in prefusion state, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Wang, Z, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-08-18
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVE
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BU of 8tve by Molmil
Langya henipavirus fusion protein in postfusion state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya henipavirus fusion protein in postfusion state
著者Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-08-18
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
3AAU
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BU of 3aau by Molmil
Bovine beta-trypsin bound to meta-diguanidino schiff base copper (II) chelate
分子名称: CALCIUM ION, COPPER (II) ION, Cationic trypsin, ...
著者Iyaguchi, D, Kawano, S, Toyota, E.
登録日2009-11-26
公開日2010-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the design of novel Schiff base metal chelate inhibitors of trypsin
Bioorg.Med.Chem., 18, 2010
3A3Z
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BU of 3a3z by Molmil
Crystal structure of the human VDR ligand binding domain bound to the synthetic agonist compound 2alpha-methyl-AMCR277A(C23S)
分子名称: (1S,2S,3R,5Z,7E,14beta,17alpha)-17-[(2S,4S)-4-(2-hydroxy-2-methylpropyl)-2-methyltetrahydrofuran-2-yl]-2-methyl-9,10-secoandrosta-5,7,10-triene-1,3-diol, SULFATE ION, Vitamin D3 receptor
著者Sato, Y, Antony, P, Huet, T, Sigueiro, R, Rochel, N, Moras, D, Structural Proteomics in Europe 2 (SPINE-2)
登録日2009-06-25
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structure-function relationships and crystal structures of the vitamin D receptor bound 2 alpha-methyl-(20S,23S)- and 2 alpha-methyl-(20S,23R)-epoxymethano-1 alpha,25-dihydroxyvitamin D3
J.Med.Chem., 53, 2010
8TBY
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BU of 8tby by Molmil
Apo Bcs1, unsymmetrized
分子名称: Mitochondrial chaperone BCS1
著者Zhan, J, Xia, D.
登録日2023-06-29
公開日2024-06-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8TPL
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BU of 8tpl by Molmil
ATP-2 state of Bcs1 (unsymmetrized)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
著者Zhan, J, Xia, D.
登録日2023-08-04
公開日2024-06-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8T7U
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BU of 8t7u by Molmil
ADP-bound Bcs1 (unsymmetrized)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1
著者Zhan, J, Xia, D.
登録日2023-06-21
公開日2024-06-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8T5U
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BU of 8t5u by Molmil
ATP-1 state of Bcs1 (C7 symmetrized)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
著者Zhan, J, Xia, D.
登録日2023-06-14
公開日2024-06-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8TI0
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BU of 8ti0 by Molmil
ATP-1 state of Bcs1 (unsymmetrized)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
著者Zhan, J, Xia, D.
登録日2023-07-18
公開日2024-06-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
3A78
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BU of 3a78 by Molmil
Crystal structure of the human VDR ligand binding domain bound to the natural metabolite 1alpha,25-dihydroxy-3-epi-vitamin D3
分子名称: (1S,3S,5Z,7E,14beta,17alpha)-9,10-secocholesta-5,7,10-triene-1,3,25-triol, SULFATE ION, Vitamin D3 receptor
著者Sato, Y, Sigueiro, R, Antony, P, Rochel, N, Moras, D.
登録日2009-09-18
公開日2010-10-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of the activation of the human Vitamin D receptor by the natural metabolite 1alpha,25-dihydroxy-3-epi-vitamin D3
To be Published
8TP1
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BU of 8tp1 by Molmil
ATP-2 state of Bcs1 (C7 symmetrized)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
著者Zhan, J, Xia, D.
登録日2023-08-04
公開日2024-06-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8T2J
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BU of 8t2j by Molmil
Structure of the catalytic domain of PPM1D/Wip1 serine/threonine phosphatase
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, MAGNESIUM ION, ...
著者Kumar, J.P, Kosek, D, Dyda, F.
登録日2023-06-06
公開日2024-06-12
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain.
J.Biol.Chem., 300, 2024
8TAT
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BU of 8tat by Molmil
CRYSTAL STRUCTURE OF R9A SPIN LABELED T4 LYSOZYME MUTANT K65R9A/R76R9A
分子名称: Endolysin, methyl 1-hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrole-3-carboxylate, radical
著者Chen, M, Hubbell, W.L, Cascio, D.
登録日2023-06-27
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Highly Ordered Nitroxide Side Chain for Distance Mapping and Monitoring Slow Structural Fluctuations in Proteins.
Appl.Magn.Reson., 55, 2024
370D
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BU of 370d by Molmil
STRUCTURAL VARIABILITY OF A-DNA IN CRYSTALS OF THE OCTAMER D(PCPCPCPGPCPGPGPG)
分子名称: DNA (5'-D(P*CP*CP*CP*GP*CP*GP*GP*G)-3'), MAGNESIUM ION
著者Fernandez, L.G, Subirana, J.A, Verdaguer, N, Pyshnyi, D, Campos, L.
登録日1997-12-19
公開日1998-07-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG)
J.Biomol.Struct.Dyn., 15, 1997
382D
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BU of 382d by Molmil
HYDRATION AND RECOGNITION OF METHYLATED CPG STEPS IN DNA.
分子名称: DNA (5'-D(*CP*CP*GP*CP*CP*GP*GP*CP*GP*G)-3'), MAGNESIUM ION
著者Mayer-Jung, C, Moras, D, Timsit, Y.
登録日1998-03-02
公開日1999-10-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Hydration and recognition of methylated CpG steps in DNA.
EMBO J., 17, 1998
2DWL
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BU of 2dwl by Molmil
Crystal structure of the PriA protein complexed with oligonucleotides
分子名称: 5'-D(*AP*(DC))-3', Primosomal protein N
著者Sasaki, K, Ose, T, Tanaka, T, Masai, H, Maenaka, K, Kohda, D.
登録日2006-08-15
公開日2006-11-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
EMBO J., 26, 2007
8U31
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BU of 8u31 by Molmil
Crystal structure of PD-1 in complex with a Fab
分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ...
著者Sun, D, Masureel, M.
登録日2023-09-07
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
2SFP
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BU of 2sfp by Molmil
ALANINE RACEMASE WITH BOUND PROPIONATE INHIBITOR
分子名称: PROPANOIC ACID, PROTEIN (ALANINE RACEMASE), PYRIDOXAL-5'-PHOSPHATE
著者Morollo, A.A, Petsko, G.A, Ringe, D.
登録日1999-02-16
公開日1999-02-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase.
Biochemistry, 38, 1999
8T7C
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BU of 8t7c by Molmil
Crystal structure of human phospholipase C gamma 2
分子名称: 1,2-ETHANEDIOL, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, CALCIUM ION
著者Chen, Y, Choi, H, Zhuang, N, Hu, L, Qian, D, Wang, J.
登録日2023-06-20
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal and cryo-EM structures of PLCg2 reveal dynamic inter-domain recognitions in autoinhibition
To Be Published
369D
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BU of 369d by Molmil
STRUCTURAL VARIABILITY OF A-DNA IN CRYSTALS OF THE OCTAMER D(PCPCPCPGPCPGPGPG)
分子名称: DNA (5'-D(P*CP*CP*CP*GP*CP*GP*GP*G)-3')
著者Fernandez, L.G, Subirana, J.A, Verdaguer, N, Pyshnyi, D, Campos, L.
登録日1997-12-19
公開日1998-07-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG)
J.Biomol.Struct.Dyn., 15, 1997
7K45
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BU of 7k45 by Molmil
SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2E12 neutralizing antibody Fab fragment (heavy chain), S2E12 neutralizing antibody Fab fragment (light chain), ...
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-14
公開日2020-10-07
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 370, 2020
383D
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BU of 383d by Molmil
Hydration and recognition of methylated CPG steps in DNA
分子名称: DNA (5'-D(*CP*(5CM)P*GP*CP*(5CM)P*GP*GP*(5CM)P*GP*G)-3'), MAGNESIUM ION
著者Mayer-Jung, C, Moras, D, Timsit, Y.
登録日1998-03-02
公開日1998-04-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hydration and Recognition of Methylated Cpg Steps in DNA
Embo J., 17, 1998

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