3AAU
Bovine beta-trypsin bound to meta-diguanidino schiff base copper (II) chelate
Summary for 3AAU
| Entry DOI | 10.2210/pdb3aau/pdb |
| Related | 3AAS 3AAV |
| Descriptor | Cationic trypsin, N,N'''-{ethane-1,2-diylbis[nitrilo(E)methylylidene(4-hydroxybenzene-3,1-diyl)]}diguanidine, CALCIUM ION, ... (5 entities in total) |
| Functional Keywords | enzyme-inhibitor complex, coordination metal based inhibitor, hydrolase, calcium, digestion, metal-binding, protease, secreted, serine protease, zymogen |
| Biological source | Bos taurus (bovine) |
| Cellular location | Secreted, extracellular space: P00760 |
| Total number of polymer chains | 1 |
| Total formula weight | 23810.33 |
| Authors | Iyaguchi, D.,Kawano, S.,Toyota, E. (deposition date: 2009-11-26, release date: 2010-04-07, Last modification date: 2023-11-01) |
| Primary citation | Iyaguchi, D.,Kawano, S.,Takada, K.,Toyota, E. Structural basis for the design of novel Schiff base metal chelate inhibitors of trypsin Bioorg.Med.Chem., 18:2076-2080, 2010 Cited by PubMed: 20202854DOI: 10.1016/j.bmc.2010.02.016 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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