3A78
Crystal structure of the human VDR ligand binding domain bound to the natural metabolite 1alpha,25-dihydroxy-3-epi-vitamin D3
Summary for 3A78
Entry DOI | 10.2210/pdb3a78/pdb |
Related | 1DB1 |
Descriptor | Vitamin D3 receptor, (1S,3S,5Z,7E,14beta,17alpha)-9,10-secocholesta-5,7,10-triene-1,3,25-triol, SULFATE ION, ... (4 entities in total) |
Functional Keywords | transcription, gene regulation, disease mutation, dna-binding, metal-binding, nucleus, phosphoprotein, receptor, transcription regulation, zinc-finger |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P11473 |
Total number of polymer chains | 1 |
Total formula weight | 30414.10 |
Authors | Sato, Y.,Sigueiro, R.,Antony, P.,Rochel, N.,Moras, D. (deposition date: 2009-09-18, release date: 2010-10-13, Last modification date: 2023-11-01) |
Primary citation | Molnar, F.,Sigueiro, R.,Sato, Y.,Antony, P.,Mourino, A.,Rochel, N.,Moras, D. Structural basis of the activation of the human Vitamin D receptor by the natural metabolite 1alpha,25-dihydroxy-3-epi-vitamin D3 To be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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