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4F5H
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BU of 4f5h by Molmil
Intercoversion of Substrate Specificity: E. coli Aspatate Aminotransferase to Tyrosine Aminotransferase: Chimera P3.
分子名称: Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4DQZ
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BU of 4dqz by Molmil
Crystal Structure of C-terminal Half of Bacterial Hen1
分子名称: Methyltransferase type 12
著者Huang, R.H, Wang, P.
登録日2012-02-16
公開日2012-08-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DRF
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BU of 4drf by Molmil
Crystal Structure of Bacterial Pnkp-C/Hen1-N Heterodimer
分子名称: GLYCEROL, Metallophosphoesterase, Methyltransferase type 12
著者Huang, R.H, Wang, P.
登録日2012-02-17
公開日2012-08-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair.
Proc.Natl.Acad.Sci.USA, 109, 2012
9IK4
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BU of 9ik4 by Molmil
Cryo-EM structure of Arabidopsis thaliana phosphate transporter PHO1;H1
分子名称: INOSITOL HEXAKISPHOSPHATE, PHOSPHATE ION, Phosphate transporter PHO1 homolog 1
著者Fang, S, Zhang, X, Zhang, P.
登録日2024-06-26
公開日2025-01-22
最終更新日2025-03-05
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis.
Nat.Plants, 11, 2025
3E6U
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BU of 3e6u by Molmil
Crystal structure of Human LanCL1
分子名称: LanC-like protein 1, ZINC ION
著者Zhang, W, Zhu, G, Li, X, Rao, Z, Zhang, C.
登録日2008-08-16
公開日2009-06-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione
Genes Dev., 23, 2009
3E73
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BU of 3e73 by Molmil
Crystal Structure of Human LanCL1 complexed with GSH
分子名称: GLUTATHIONE, LanC-like protein 1, ZINC ION
著者Zhang, W, Zhu, G, Li, X, Rao, Z, Zhang, C.
登録日2008-08-17
公開日2009-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione
Genes Dev., 23, 2009
7T63
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BU of 7t63 by Molmil
Crystal structure of a delta 6 18:0-ACP desaturase from Thunbergia laurifolia
分子名称: DESATURASE, FE (II) ION
著者Liu, Q, Chai, J, Shanklin, J.
登録日2021-12-13
公開日2022-07-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Divergent evolution of extreme production of variant plant monounsaturated fatty acids.
Proc.Natl.Acad.Sci.USA, 119, 2022
9D8U
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BU of 9d8u by Molmil
Crystal structure of CDK6 in complex with atirmociclib
分子名称: Atirmociclib, Cyclin-dependent kinase 6
著者Johnson, E, Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A.
登録日2024-08-20
公開日2025-03-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety.
Cancer Cell, 43, 2025
9JF8
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BU of 9jf8 by Molmil
Cryo-EM structure of the EXS domain of Arabidopsis thaliana phosphate transporter PHO1;H1
分子名称: PHOSPHATE ION, Phosphate transporter PHO1 homolog 1
著者Fang, S, Zhang, X, Zhang, P.
登録日2024-09-04
公開日2025-01-22
最終更新日2025-03-05
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis.
Nat.Plants, 11, 2025
4F5K
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BU of 4f5k by Molmil
Substrate Specificity Conversion of Aspartate Aminotransferase to Tyrosine Aminotransferase By The JANUS Algorithm: Chimera P6.
分子名称: Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5G
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BU of 4f5g by Molmil
Rational Design and Directed Evolution of E. coli Apartate Aminotransferase to Tyrosine Aminotransferase: Mutant P2.
分子名称: Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5L
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BU of 4f5l by Molmil
A Theoretical Optimized Mutant for the Conversion of Substrate Specificity and Activity of Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P7.
分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-05-15
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Janus: an algorithm for ranking functional importance of residues from protein sequence alignments.
To be Published
5TSB
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BU of 5tsb by Molmil
Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Cd2+
分子名称: CADMIUM ION, Membrane protein
著者Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J.
登録日2016-10-28
公開日2017-09-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway.
Sci Adv, 3, 2017
5TSA
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BU of 5tsa by Molmil
Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Zn2+
分子名称: CADMIUM ION, Membrane protein, ZINC ION
著者Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J.
登録日2016-10-28
公開日2017-09-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway.
Sci Adv, 3, 2017
3NPZ
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BU of 3npz by Molmil
Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)
分子名称: Prolactin, Prolactin receptor
著者Van Agthoven, J, England, P, Goffin, V, Broutin, I.
登録日2010-06-29
公開日2010-10-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.
J.Mol.Biol., 404, 2010
5WPW
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BU of 5wpw by Molmil
Crystal structure of coconut allergen cocosin
分子名称: 11S globulin isoform 1
著者Jin, T, Zhang, Y.
登録日2016-11-21
公開日2017-10-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.847 Å)
主引用文献Crystal Structure of Cocosin, A Potential Food Allergen from Coconut (Cocos nucifera)
J. Agric. Food Chem., 65, 2017
8JGF
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BU of 8jgf by Molmil
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22
分子名称: BAM8-22, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, J.P, Xu, H.E, Yang, F, Liu, Z.M, Guo, L.L, Zhang, Y.M, Fang, G.X, Tie, L, Zhuang, Y.M, Xue, C.Y.
登録日2023-05-20
公開日2024-01-10
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Nat Commun, 14, 2023
8JGG
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BU of 8jgg by Molmil
CryoEM structure of Gi-coupled MRGPRX1 with peptide agonist BAM8-22
分子名称: BAM8-22, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, J.P, Xu, H.E, Ynag, F, Liu, Z.M, Guo, L.L, Zhang, Y.M, Fang, G.X, Tie, L, Zhuang, Y.M, Xue, C.Y.
登録日2023-05-20
公開日2024-01-10
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Nat Commun, 14, 2023
8JGB
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BU of 8jgb by Molmil
CryoEM structure of Gi-coupled MRGPRX1 with peptide agonist CNF-Tx2
分子名称: Conorfamide-Tx2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, J.P, Xu, H.E, Yang, F, Liu, Z.M, Guo, L.L, Zhang, Y.M, Fang, G.X, Tie, L, Zhuang, Y.M, Xue, C.Y.
登録日2023-05-20
公開日2024-01-10
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Nat Commun, 14, 2023
4NI7
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BU of 4ni7 by Molmil
Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025)
分子名称: Interleukin-6, SODIUM ION, SOMAmer SL1025
著者Davies, D, Edwards, T, Gelinas, A, Jarvis, T, Clifton, M.C.
登録日2013-11-05
公開日2014-01-22
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand.
J.Biol.Chem., 289, 2014
4NI9
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BU of 4ni9 by Molmil
Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025), FORM 2
分子名称: Interleukin-6, SODIUM ION, SOMAmer SL1025
著者Davies, D, Edwards, T, Gelinas, A, Jarvis, T, Clifton, M.C.
登録日2013-11-05
公開日2014-01-22
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand.
J.Biol.Chem., 289, 2014
3PDV
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BU of 3pdv by Molmil
Structure of the PDlim2 PDZ domain in complex with the C-terminal 6-peptide extension of NS1
分子名称: PDZ and LIM domain protein 2, C-teminal peptide from Nonstructural protein 1, SODIUM ION
著者Li, X.
登録日2010-10-25
公開日2011-09-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1
Plos One, 6, 2011
4PXQ
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BU of 4pxq by Molmil
Crystal structure of D-glucuronyl C5-epimerase in complex with heparin hexasaccharide
分子名称: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, D-glucuronyl C5 epimerase B
著者Ke, J, Qin, Y, Gu, X, Tan, J, Brunzelle, J.S, Xu, H.E, Ding, K.
登録日2014-03-24
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Functional Study of d-Glucuronyl C5-epimerase.
J.Biol.Chem., 290, 2015
5I3O
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BU of 5i3o by Molmil
Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
分子名称: BMP-2-inducible protein kinase, N-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1H-indazol-3-yl)cyclopropanecarboxamide, SULFATE ION
著者Counago, R.M, Sorrell, F.J, Krojer, T, Savitsky, P, Elkins, J.M, Axtman, A, Drewry, D, Wells, C, Zhang, C, Zuercher, W, Willson, T.M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Arruda, P, Gileadi, O, Structural Genomics Consortium (SGC)
登録日2016-02-10
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
To Be Published
5I3R
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BU of 5i3r by Molmil
Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
分子名称: BMP-2-inducible protein kinase, N-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1H-indazol-3-yl]cyclopropanecarboxamide, PHOSPHATE ION
著者Counago, R.M, Sorrell, F.J, Krojer, T, Savitsky, P, Elkins, J.M, Axtman, A, Drewry, D, Wells, C, Zhang, C, Zuercher, W, Willson, T.M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Arruda, P, Gileadi, O, Structural Genomics Consortium (SGC)
登録日2016-02-10
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
To Be Published

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件を2025-07-09に公開中

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