4G5Q
| Structure of LGN GL4/Galphai1 complex | 分子名称: | CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W. | 登録日 | 2012-07-18 | 公開日 | 2012-09-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins To be Published
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4MBS
| Crystal Structure of the CCR5 Chemokine Receptor | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4,4-difluoro-N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl}-1-phenylpropyl]cyclohexanecarboxamide, Chimera protein of C-C chemokine receptor type 5 and Rubredoxin, ... | 著者 | Tan, Q, Zhu, Y, Han, G.W, Li, J, Fenalti, G, Liu, H, Cherezov, V, Stevens, R.C, GPCR Network (GPCR), Zhao, Q, Wu, B. | 登録日 | 2013-08-19 | 公開日 | 2013-09-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science, 341, 2013
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6ADQ
| Respiratory Complex CIII2CIV2SOD2 from Mycobacterium smegmatis | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | 著者 | Gong, H.R, Xu, A, Gao, R.G, Ji, W.X, Wang, S.H, Wang, Q, Li, J, Rao, Z.H. | 登録日 | 2018-08-01 | 公開日 | 2018-11-14 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | An electron transfer path connects subunits of a mycobacterial respiratory supercomplex. Science, 362, 2018
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6KUZ
| E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01 | 分子名称: | 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Chen, X, Hu, Y.L, Li, X.K, Guo, Y, Li, J. | 登録日 | 2019-09-03 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase. Chem Sci, 11, 2020
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7TYM
| Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry | 分子名称: | Insulin receptor-related protein | 著者 | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | 登録日 | 2022-02-13 | 公開日 | 2023-02-15 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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7TYJ
| Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was focused on one of two halves with C1 symmetry applied | 分子名称: | Insulin receptor-related protein | 著者 | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | 登録日 | 2022-02-13 | 公開日 | 2023-02-15 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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7TYK
| Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was applied with C2 symmetry | 分子名称: | Insulin receptor-related protein | 著者 | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | 登録日 | 2022-02-13 | 公開日 | 2023-02-15 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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4NX2
| Crystal structure of DCYRS complexed with DCY | 分子名称: | 3,5-dichloro-L-tyrosine, Tyrosine--tRNA ligase | 著者 | Wang, J, Gong, W, Li, J, Gao, F, Li, H. | 登録日 | 2013-12-08 | 公開日 | 2014-09-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers. J.Am.Chem.Soc., 136, 2014
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6KOE
| X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis | 分子名称: | 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, ... | 著者 | Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J. | 登録日 | 2019-08-09 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | 主引用文献 | Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KOC
| X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis complexed with 3-iodo-N-oxo-2-heptyl-4-hydroxyquinoline | 分子名称: | 2-heptyl-3-iodanyl-1-oxidanyl-quinolin-4-one, AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, ... | 著者 | Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J. | 登録日 | 2019-08-09 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site. Proc.Natl.Acad.Sci.USA, 117, 2020
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1MI1
| Crystal Structure of the PH-BEACH Domain of Human Neurobeachin | 分子名称: | Neurobeachin | 著者 | Jogl, G, Shen, Y, Gebauer, D, Li, J, Wiegmann, K, Kashkar, H, Kroenke, M, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2002-08-21 | 公開日 | 2002-09-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain. EMBO J., 21, 2002
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6LTJ
| Structure of nucleosome-bound human BAF complex | 分子名称: | AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... | 著者 | He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. | 登録日 | 2020-01-22 | 公開日 | 2020-02-12 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of nucleosome-bound human BAF complex. Science, 367, 2020
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3UJK
| Crystal structure of protein phosphatase ABI2 | 分子名称: | MAGNESIUM ION, Protein phosphatase 2C 77 | 著者 | Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E. | 登録日 | 2011-11-07 | 公開日 | 2012-02-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science, 335, 2012
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3UC3
| The crystal structure of Snf1-related kinase 2.3 | 分子名称: | COBALT (II) ION, Serine/threonine-protein kinase SRK2I | 著者 | Zhou, X.E, Ng, L.-M, Soon, F.-F, Kovach, A, Suino-Powell, K.M, Li, J, Melcher, K, Xu, H.E. | 登録日 | 2011-10-25 | 公開日 | 2011-12-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases. Proc.Natl.Acad.Sci.USA, 108, 2011
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2ZJG
| Crystal structural of mouse kynurenine aminotransferase III | 分子名称: | GLYCEROL, Kynurenine-oxoglutarate transaminase 3 | 著者 | Han, Q, Cai, T, Tagle, D.A, Robinson, H, Li, J. | 登録日 | 2008-03-07 | 公開日 | 2009-01-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and functional characterization of mouse kynurenine aminotransferase III To be Published
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3UJG
| Crystal structure of SnRK2.6 in complex with HAB1 | 分子名称: | MAGNESIUM ION, Protein phosphatase 2C 16, SULFATE ION, ... | 著者 | Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E. | 登録日 | 2011-11-07 | 公開日 | 2012-02-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science, 335, 2012
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3N2Y
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2ZKJ
| Crystal structure of human PDK4-ADP complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Li, J, Chuang, D.T. | 登録日 | 2008-03-25 | 公開日 | 2008-08-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Pyruvate Dehydrogenase Kinase-4 Structures Reveal a Metastable Open Conformation Fostering Robust Core-free Basal Activity J.Biol.Chem., 283, 2008
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3E2Y
| Crystal structure of mouse kynurenine aminotransferase III in complex with glutamine | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLUTAMINE, GLYCEROL, ... | 著者 | Han, Q, Robinson, R, Cai, T, Tagle, D.A, Li, J. | 登録日 | 2008-08-06 | 公開日 | 2008-12-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Correction for Han et al., "Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III". Mol. Cell. Biol., 38, 2018
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3E2Z
| Crystal structure of mouse kynurenine aminotransferase III in complex with kynurenine | 分子名称: | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ... | 著者 | Han, Q, Robinson, R, Cai, T, Tagle, D.A, Li, J. | 登録日 | 2008-08-06 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Correction for Han et al., "Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III". Mol. Cell. Biol., 38, 2018
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8FNE
| phiPA3 PhuN Tetramer, p2 | 分子名称: | Maltose/maltodextrin-binding periplasmic protein, PhuN | 著者 | Nieweglowska, E.S, Brilot, A.F, Mendez-Moran, M, Kokontis, C, Baek, M, Li, J, Cheng, Y, Baker, D, Bondy-Denomy, J, Agard, D.A. | 登録日 | 2022-12-27 | 公開日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The phi PA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice. Nat Commun, 14, 2023
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8FV5
| Representation of 16-mer phiPA3 PhuN Lattice, p2 | 分子名称: | Maltose/maltodextrin-binding periplasmic protein, phiPA3 PhuN | 著者 | Nieweglowska, E.S, Brilot, A.F, Mendez-Moran, M, Kokontis, C, Baek, M, Li, J, Cheng, Y, Baker, D, Bondy-Denomy, J, Agard, D.A. | 登録日 | 2023-01-18 | 公開日 | 2023-03-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.21 Å) | 主引用文献 | The phi PA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice. Nat Commun, 14, 2023
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3E2F
| Crystal structure of mouse kynurenine aminotransferase III, PLP-bound form | 分子名称: | GLYCEROL, Kynurenine-oxoglutarate transaminase 3 | 著者 | Han, Q, Robinson, R, Cai, T, Tagle, D.A, Li, J. | 登録日 | 2008-08-05 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Correction for Han et al., "Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III". Mol. Cell. Biol., 38, 2018
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3H84
| Crystal structure of GET3 | 分子名称: | ATPase GET3, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Hu, J, Li, J, Qian, X, Sha, B. | 登録日 | 2009-04-28 | 公開日 | 2009-12-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion. Plos One, 4, 2009
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5DQU
| Crystal Structure of Cas-DNA-10 complex | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*TP*TP*TP*T)-3'), ... | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | 登録日 | 2015-09-15 | 公開日 | 2015-11-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems. Cell, 163, 2015
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