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4RVP
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BU of 4rvp by Molmil
Crystal structure of superoxide dismutase from sedum alfredii
分子名称: ZINC ION, superoxide dismutase
著者Qiu, R, Li, C, Zhai, J, Tang, L, Zhang, H, Yuan, M, Hu, X.
登録日2014-11-27
公開日2015-12-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The positive effects of Cd and Cd-Zn relationship in the Zn-related physiological processes involved in growth in the Zn/Cd hyperaccumulator Sedum alfredii
To be Published
3ED0
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BU of 3ed0 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, BENZAMIDINE, ...
著者Zhang, L, Zhang, H, Liu, W, Guo, Y, Shen, X, Jiang, H.
登録日2008-09-02
公開日2009-07-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
BMC MICROBIOL., 9, 2009
4MGJ
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BU of 4mgj by Molmil
Crystal structure of cytochrome P450 2B4 F429H in complex with 4-CPI
分子名称: 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
著者Yang, Y, Zhang, H, Usharani, D, Bu, W, Im, S, Tarasev, M, Rwere, F, Meagher, J, Sun, C, Stuckey, J, Shaik, S, Waskell, L.
登録日2013-08-28
公開日2014-08-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structural and Functional Characterization of a Cytochrome P450 2B4 F429H Mutant with an Axial Thiolate-Histidine Hydrogen Bond.
Biochemistry, 53, 2014
4O5P
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BU of 4o5p by Molmil
Crystal structure of an uncharacterized protein from Pseudomonas aeruginosa
分子名称: Uncharacterized protein
著者Hu, H.D, Gao, Z.Q, Zhang, H, Dong, Y.H.
登録日2013-12-19
公開日2014-08-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structure of the type VI secretion phospholipase effector Tle1 provides insight into its hydrolysis and membrane targeting.
Acta Crystallogr.,Sect.D, 70, 2014
7LJC
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BU of 7ljc by Molmil
Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein
分子名称: (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ...
著者Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
登録日2021-01-28
公開日2021-03-03
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
7LJD
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BU of 7ljd by Molmil
Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein
分子名称: 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ...
著者Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
登録日2021-01-28
公開日2021-03-03
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
4I8O
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BU of 4i8o by Molmil
Crystal structure of the toxin RnlA from Escherichia coli
分子名称: TOXIN RNLA
著者Wei, Y, Gao, Z.Q, Zhang, H, Dong, Y.H.
登録日2012-12-04
公開日2013-10-23
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Structure-function studies of Escherichia coli RnlA reveal a novel toxin structure involved in bacteriophage resistance.
Mol.Microbiol., 90, 2013
4HZ9
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BU of 4hz9 by Molmil
Crystal structure of the type VI native effector-immunity complex Tae3-Tai3 from Ralstonia pickettii
分子名称: Putative cytoplasmic protein, Putative periplasmic protein
著者Dong, C, Zhang, H, Gao, Z.Q, Dong, Y.H.
登録日2012-11-14
公開日2013-08-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3
Biochem.J., 454, 2013
4HZB
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BU of 4hzb by Molmil
Crystal structure of the type VI SeMet effector-immunity complex Tae3-Tai3 from Ralstonia pickettii
分子名称: Putative cytoplasmic protein, Putative periplasmic protein
著者Dong, C, Zhang, H, Gao, Z.Q, Dong, Y.H.
登録日2012-11-15
公開日2013-08-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3
Biochem.J., 454, 2013
8WLD
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BU of 8wld by Molmil
Cryo-EM structure of SIR2/HerA antiphage complex
分子名称: Helicase HerA central domain-containing protein, SIR2-like domain-containing protein
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-09-29
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Cryo-EM structure of SIR2/HerA antiphage complex
To Be Published
8WIV
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BU of 8wiv by Molmil
Cryo-EM structure of a bacterial protein
分子名称: Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-09-25
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Cryo-EM structure of a bacterial protein
To Be Published
8WOC
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BU of 8woc by Molmil
Cryo-EM structure of SIR2/HerA complex
分子名称: Helicase HerA central domain-containing protein, SIR2-like domain-containing protein
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-10-07
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Cryo-EM structure of a bacterial protein
To Be Published
8WOF
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BU of 8wof by Molmil
Cryo-EM structure of SIR2/HerA complex
分子名称: Helicase HerA central domain-containing protein, SIR2-like domain-containing protein
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-10-07
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of a bacterial protein
To Be Published
8WOD
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BU of 8wod by Molmil
Cryo-EM structure of SIR2/HerA complex
分子名称: Helicase HerA central domain-containing protein, SIR2-like domain-containing protein
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-10-07
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Cryo-EM structure of a bacterial protein
To Be Published
8W9L
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BU of 8w9l by Molmil
Cryo-EM structure of PsSIR2
分子名称: SIR2-like domain-containing protein
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-09-05
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of PsSIR2
To Be Published
8W9X
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BU of 8w9x by Molmil
Structure of a bacterial protein
分子名称: SIR2-like domain-containing protein
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-09-06
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献structure of a bacterial protein
To Be Published
8WJ3
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BU of 8wj3 by Molmil
Cryo-EM structure of a bacterial protein
分子名称: Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-09-25
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Cryo-EM structure of a bacterial protein
To Be Published
8WK0
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BU of 8wk0 by Molmil
Cryo-EM structure of a bacterial protein
分子名称: Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2023-09-26
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Cryo-EM structure of a bacterial protein
To Be Published
8YQF
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BU of 8yqf by Molmil
Structure of PsSIR2 tetradecamer
分子名称: SIR2-like domain-containing protein
著者Yu, G, Liao, F, Li, X, Li, Z, Zhang, H.
登録日2024-03-19
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Structure of a bacterial protein
To Be Published
6LG4
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BU of 6lg4 by Molmil
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-1024
分子名称: 7-chloranyl-5-nitro-quinolin-8-ol, Bromodomain-containing protein 4
著者Xu, H, Zuo, Y, Zhang, H.
登録日2019-12-04
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
6LG8
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BU of 6lg8 by Molmil
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-2138
分子名称: 2-azanyl-5-fluoranyl-4-imidazol-1-yl-quinolin-8-ol, Bromodomain-containing protein 4
著者Xu, H, Zuo, Y, Zhang, H.
登録日2019-12-04
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
8HEF
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BU of 8hef by Molmil
The Crystal structure of deuterated S-217622 (Ensitrelvir) bound to the main protease (3CLpro/Mpro) of SARS-CoV-2
分子名称: 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, GLYCEROL
著者Yan, M, Zhang, H.
登録日2022-11-08
公開日2023-04-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Synthesis of deuterated S-217622 (Ensitrelvir) with antiviral activity against coronaviruses including SARS-CoV-2.
Antiviral Res., 213, 2023
5H14
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BU of 5h14 by Molmil
EED in complex with an allosteric PRC2 inhibitor EED666
分子名称: 2-[3-(3,5-dimethylpyrazol-1-yl)-4-nitro-phenyl]-3,4-dihydro-1H-isoquinoline, GLYCEROL, Histone-lysine N-methyltransferase EZH2, ...
著者Zhao, K, Zhao, M, Luo, X, Zhang, H.
登録日2016-10-08
公開日2017-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
5H15
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BU of 5h15 by Molmil
EED in complex with PRC2 allosteric inhibitor EED709
分子名称: (3R,4S)-1-[(2-methoxyphenyl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED
著者Zhao, K, Zhao, M, Luo, X, Zhang, H.
登録日2016-10-08
公開日2017-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
5H13
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BU of 5h13 by Molmil
EED in complex with PRC2 allosteric inhibitor EED396
分子名称: 4-azanylidene-2-(3-methoxy-4-propan-2-yloxy-phenyl)-6,7-dihydro-[1,3]benzodioxolo[6,5-a]quinolizine-3-carbonitrile, GLYCEROL, PRASEODYMIUM ION, ...
著者Zhao, K, Zhao, M, Luo, X, Zhang, H.
登録日2016-10-08
公開日2017-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017

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