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5E34
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Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1) with LSTa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E32
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BU of 5e32 by Molmil
Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E2Y
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BU of 5e2y by Molmil
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E99
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Bovine Fab fragment F08_B11
分子名称: Fab F08_B11 heavy chain, Fab F08_B11 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2015-10-14
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
5E35
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Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1) with LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5BZD
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BU of 5bzd by Molmil
Crystal Structure of PCDN-27A, an antibody from the PCDN family of HIV-1 antibodies
分子名称: 5G8 HIV Antibody heavy chain, 5G8 HIV Antibody light chain, GLYCEROL
著者Garces, F, WILSON, I.A.
登録日2015-06-11
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
Immunity, 44, 2016
5C7K
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BU of 5c7k by Molmil
Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 8ANC195 heavy chain, ...
著者Kong, L, Stanfield, R.L, Wilson, I.A.
登録日2015-06-24
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.6019 Å)
主引用文献Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Acta Crystallogr.,Sect.D, 71, 2015
5CEX
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BU of 5cex by Molmil
Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
分子名称: Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ...
著者Garces, F, Wilson, I.A.
登録日2015-07-07
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5E30
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BU of 5e30 by Molmil
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) with LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
1A3L
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BU of 1a3l by Molmil
CATALYSIS OF A DISFAVORED REACTION: AN ANTIBODY EXO DIELS-ALDERASE-TSA-INHIBITOR COMPLEX AT 1.95 A RESOLUTION
分子名称: 1-CARBOXY-1'-[(DIMETHYLAMINO)-CARBONYL]FERROCENE, IMMUNOGLOBULIN FAB 13G5 (HEAVY CHAIN), IMMUNOGLOBULIN FAB 13G5 (LIGHT CHAIN)
著者Heine, A, Wilson, I.A.
登録日1998-01-22
公開日1999-02-16
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.
Science, 279, 1998
3P3T
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BU of 3p3t by Molmil
Human transthyretin (TTR) complexed with 4-(3-(2-flourophenoxy)propyl)-3,5-dimethyl-1H-pyrazole
分子名称: 4-[3-(2-fluorophenoxy)propyl]-3,5-dimethyl-1H-pyrazole, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2010-10-05
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med, 3, 2011
3P3R
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BU of 3p3r by Molmil
Transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)(2-fluorophenyl)methanone
分子名称: (3,4-dihydroxy-5-nitrophenyl)(2-fluorophenyl)methanone, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2010-10-05
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med, 3, 2011
1AHW
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BU of 1ahw by Molmil
A COMPLEX OF EXTRACELLULAR DOMAIN OF TISSUE FACTOR WITH AN INHIBITORY FAB (5G9)
分子名称: IMMUNOGLOBULIN FAB 5G9 (HEAVY CHAIN), IMMUNOGLOBULIN FAB 5G9 (LIGHT CHAIN), TISSUE FACTOR
著者Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A.
登録日1997-04-10
公開日1998-02-25
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.5G9 complex.
J.Mol.Biol., 275, 1998
1ACY
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BU of 1acy by Molmil
CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1
分子名称: HIV-1 GP120 (MN ISOLATE), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), IGG1-KAPPA 59.1 FAB (LIGHT CHAIN)
著者Ghiara, J.B, Wilson, I.A.
登録日1994-02-10
公開日1994-07-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the principal neutralization site of HIV-1.
Science, 264, 1994
1C1E
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BU of 1c1e by Molmil
CRYSTAL STRUCTURE OF A DIELS-ALDERASE CATALYTIC ANTIBODY 1E9 IN COMPLEX WITH ITS HAPTEN
分子名称: 1,7,8,9,10,10-HEXACHLORO-4-METHYL-4-AZA-TRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE, CATALYTIC ANTIBODY 1E9 (HEAVY CHAIN), CATALYTIC ANTIBODY 1E9 (LIGHT CHAIN), ...
著者Xu, J, Wilson, I.A.
登録日1999-07-22
公開日2000-03-01
最終更新日2013-01-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolution of shape complementarity and catalytic efficiency from a primordial antibody template.
Science, 286, 1999
1AI1
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BU of 1ai1 by Molmil
HIV-1 V3 LOOP MIMIC
分子名称: AIB142, IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), IGG1-KAPPA 59.1 FAB (LIGHT CHAIN)
著者Ghiara, J.B, Wilson, I.A.
登録日1996-11-06
公開日1997-05-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.
J.Mol.Biol., 266, 1997
1C16
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BU of 1c16 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE GAMMA/DELTA T CELL LIGAND T22
分子名称: MHC-LIKE PROTEIN T22, PROTEIN (BETA-2-MICROGLOBULIN)
著者Wingren, C, Crowley, M.P, Degano, M, Chien, Y, Wilson, I.A.
登録日1999-07-20
公開日2000-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of a gammadelta T cell receptor ligand T22: a truncated MHC-like fold.
Science, 287, 2000
3P3S
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BU of 3p3s by Molmil
Human transthyretin (TTR) complexed with (Z)-5-(3,5-dibromo-4-hydroxybenzylidene)-imino-1-methylimidazolidin-4-one
分子名称: (5Z)-2-amino-5-(3,5-dibromo-4-hydroxybenzylidene)-1-methyl-1,5-dihydro-4H-imidazol-4-one, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2010-10-05
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med, 3, 2011
3P3U
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Human transthyretin (TTR) complexed with 5-(2-ethoxyphenyl)-3-(pyridin-4-yl)-1,2,4-oxadiazole
分子名称: 4-[5-(2-ethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2010-10-05
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med, 3, 2011
1C5B
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BU of 1c5b by Molmil
DECARBOXYLASE CATALYTIC ANTIBODY 21D8 UNLIGANDED FORM
分子名称: CHIMERIC DECARBOXYLASE ANTIBODY 21D8
著者Hotta, K, Wilson, I.A.
登録日1999-11-08
公開日2000-10-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.
J.Mol.Biol., 302, 2000
1C5C
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BU of 1c5c by Molmil
DECARBOXYLASE CATALYTIC ANTIBODY 21D8-HAPTEN COMPLEX
分子名称: 2-ACETYLAMINO-NAPTHALENE-1,5-DISULFONIC ACID, CHIMERIC DECARBOXYLASE ANTIBODY 21D8, GLYCEROL
著者Hotta, K, Wilson, I.A.
登録日1999-11-09
公開日2000-10-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.
J.Mol.Biol., 302, 2000
1AXT
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BU of 1axt by Molmil
IMMUNE VERSUS NATURAL SELECTION: ANTIBODY ALDOLASES WITH THE RATES OF NATURAL ENZYMES
分子名称: IMMUNOGLOBULIN IGG2A
著者Heine, A, Wilson, I.A.
登録日1997-10-20
公開日1998-10-28
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Immune versus natural selection: antibody aldolases with enzymic rates but broader scope.
Science, 278, 1997
1CD1
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BU of 1cd1 by Molmil
CD1(MOUSE) ANTIGEN PRESENTING MOLECULE
分子名称: CD1
著者Zeng, Z.H, Segelke, B.W, Wilson, I.A.
登録日1997-04-02
公開日1997-10-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove.
Science, 277, 1997
1D5T
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GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM
分子名称: GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, SULFATE ION
著者Peng, L, Zeng, K, Heine, A, Moyer, B, Greasley, S.E, Kuhn, P, Balch, W.E, Wilson, I.A.
登録日1999-10-11
公開日2000-10-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling.
Traffic, 1, 2000
6MNF
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Anti-HIV-1 Fab 2G12 + Man8 re-refinement
分子名称: Fab 2G12, light chain, Fab 2g12, ...
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-10-01
公開日2018-10-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005

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