5EX3
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![BU of 5ex3 by Molmil](/molmil-images/mine/5ex3) | Crystal structure of human SMYD3 in complex with a VEGFR1 peptide | 分子名称: | ACETIC ACID, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Qiao, Q, Fu, W, Liu, N, Wang, M, Min, J, Zhu, B, Xu, R.M, Yang, N. | 登録日 | 2015-11-23 | 公開日 | 2016-03-09 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.408 Å) | 主引用文献 | Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase J.Biol.Chem., 291, 2016
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5BTR
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![BU of 5btr by Molmil](/molmil-images/mine/5btr) | Crystal structure of SIRT1 in complex with resveratrol and an AMC-containing peptide | 分子名称: | AMC-containing peptide, NAD-dependent protein deacetylase sirtuin-1, RESVERATROL, ... | 著者 | Cao, D, Wang, M, Qiu, X, Liu, D, Jiang, H, Yang, N, Xu, R.M. | 登録日 | 2015-06-03 | 公開日 | 2015-07-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol Genes Dev., 29, 2015
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5C3I
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![BU of 5c3i by Molmil](/molmil-images/mine/5c3i) | Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 | 分子名称: | DNA replication licensing factor MCM2,MCM2, Histone H3.1, Histone H4, ... | 著者 | Wang, H, Wang, M, Yang, N, Xu, R.M. | 登録日 | 2015-06-17 | 公開日 | 2015-07-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Protein Cell, 6, 2015
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5CQQ
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![BU of 5cqq by Molmil](/molmil-images/mine/5cqq) | Crystal structure of the Drosophila Zeste DNA binding domain in complex with DNA | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*AP*CP*GP*AP*GP*TP*GP*GP*AP*AP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*TP*TP*CP*CP*AP*CP*TP*CP*GP*TP*TP*TP*TP*T)-3'), Regulatory protein zeste | 著者 | Gao, G.N, Wang, M, Yang, N, Huang, Y, Xu, R.M. | 登録日 | 2015-07-22 | 公開日 | 2015-11-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of Zeste-DNA Complex Reveals a New Modality of DNA Recognition by Homeodomain-Like Proteins J.Mol.Biol., 427, 2015
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4PW6
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![BU of 4pw6 by Molmil](/molmil-images/mine/4pw6) | structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex II | 分子名称: | 5hmC-containing DNA1, 5hmC-containing DNA2, E3 ubiquitin-protein ligase UHRF2 | 著者 | Zhou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M. | 登録日 | 2014-03-18 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.789 Å) | 主引用文献 | Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2. Mol.Cell, 54, 2014
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4PW5
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![BU of 4pw5 by Molmil](/molmil-images/mine/4pw5) | structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex I | 分子名称: | 5hmC-containing DNA1, 5hmC-containing DNA2, E3 ubiquitin-protein ligase UHRF2 | 著者 | ZHou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M. | 登録日 | 2014-03-18 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | 主引用文献 | Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2. Mol.Cell, 54, 2014
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4PW7
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![BU of 4pw7 by Molmil](/molmil-images/mine/4pw7) | structure of UHRF2-SRA in complex with a 5mC-containing DNA | 分子名称: | 5mC-containing DNA1, 5mC-containing DNA2, E3 ubiquitin-protein ligase UHRF2 | 著者 | ZHou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M. | 登録日 | 2014-03-19 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2. Mol.Cell, 54, 2014
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4Q5W
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![BU of 4q5w by Molmil](/molmil-images/mine/4q5w) | Crystal structure of extended-Tudor 9 of Drosophila melanogaster | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Maternal protein tudor | 著者 | Ren, R, Liu, H, Wang, W, Wang, M, Yang, N, Dong, Y, Gong, W, Lehmann, R, Xu, R.M. | 登録日 | 2014-04-17 | 公開日 | 2014-05-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Structure and domain organization of Drosophila Tudor Cell Res., 24, 2014
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4Q5Y
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![BU of 4q5y by Molmil](/molmil-images/mine/4q5y) | Crystal structure of extended-Tudor 10-11 of Drosophila melanogaster | 分子名称: | Maternal protein tudor | 著者 | Liu, H, Ren, R, Wang, W, Wang, M, Yang, N, Dong, Y, Gong, W, Lehmann, R, Xu, R.M. | 登録日 | 2014-04-18 | 公開日 | 2014-05-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and domain organization of Drosophila Tudor Cell Res., 24, 2014
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4KUL
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![BU of 4kul by Molmil](/molmil-images/mine/4kul) | Crystal structure of N-terminal acetylated yeast Sir3 BAH domain V83P mutant | 分子名称: | Regulatory protein SIR3 | 著者 | Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M. | 登録日 | 2013-05-22 | 公開日 | 2013-08-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain. Nat.Struct.Mol.Biol., 20, 2013
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4KUI
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![BU of 4kui by Molmil](/molmil-images/mine/4kui) | Crystal structure of N-terminal acetylated yeast Sir3 BAH domain | 分子名称: | ACETIC ACID, ISOPROPYL ALCOHOL, Regulatory protein SIR3 | 著者 | Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M. | 登録日 | 2013-05-22 | 公開日 | 2013-08-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain. Nat.Struct.Mol.Biol., 20, 2013
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4KUD
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![BU of 4kud by Molmil](/molmil-images/mine/4kud) | Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast nucleosome core particle | 分子名称: | Histone H2A.2, Histone H2B.1, Histone H3, ... | 著者 | Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M. | 登録日 | 2013-05-22 | 公開日 | 2013-08-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.203 Å) | 主引用文献 | N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain. Nat.Struct.Mol.Biol., 20, 2013
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5E5A
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![BU of 5e5a by Molmil](/molmil-images/mine/5e5a) | Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle | 分子名称: | C-terminal domain of Regulatory protein IE1, DNA (146-MER), Histone H2A, ... | 著者 | Fang, Q, Chen, P, Wang, M, Fang, J, Yang, N, Li, G, Xu, R.M. | 登録日 | 2015-10-08 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.809 Å) | 主引用文献 | Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome Elife, 5, 2016
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5EX7
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![BU of 5ex7 by Molmil](/molmil-images/mine/5ex7) | Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA | 分子名称: | Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3') | 著者 | Wang, Y, Yu, Z, Wang, M, Liu, C.P, Yang, N, Xu, R.M. | 登録日 | 2015-11-23 | 公開日 | 2015-12-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA To Be Published
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5H1L
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![BU of 5h1l by Molmil](/molmil-images/mine/5h1l) | Crystal structure of WD40 repeat domains of Gemin5 in complex with 7-nt U4 snRNA fragment | 分子名称: | GLYCEROL, Gem-associated protein 5, U4 snRNA (5'-R(*AP*UP*UP*UP*UP*UP*G)-3') | 著者 | Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M. | 登録日 | 2016-10-10 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5 Genes Dev., 30, 2016
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5H1M
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![BU of 5h1m by Molmil](/molmil-images/mine/5h1m) | Crystal structure of WD40 repeat domains of Gemin5 in complex with M7G | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Gem-associated protein 5 | 著者 | Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M. | 登録日 | 2016-10-10 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.492 Å) | 主引用文献 | Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5 Genes Dev., 30, 2016
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5H1K
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![BU of 5h1k by Molmil](/molmil-images/mine/5h1k) | Crystal structure of WD40 repeat domains of Gemin5 in complex with 13-nt U4 snRNA fragment | 分子名称: | Gem-associated protein 5, U4 snRNA (5'-R(*GP*CP*AP*AP*UP*UP*UP*UP*UP*GP*AP*CP*A)-3') | 著者 | Wang, Y, Jin, W, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M. | 登録日 | 2016-10-10 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5 Genes Dev., 30, 2016
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5H1J
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![BU of 5h1j by Molmil](/molmil-images/mine/5h1j) | Crystal structure of WD40 repeat domains of Gemin5 | 分子名称: | Gem-associated protein 5 | 著者 | Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M. | 登録日 | 2016-10-10 | 公開日 | 2016-11-23 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5 Genes Dev., 30, 2016
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2IV0
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![BU of 2iv0 by Molmil](/molmil-images/mine/2iv0) | Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers | 分子名称: | CHLORIDE ION, ISOCITRATE DEHYDROGENASE, ZINC ION | 著者 | Stokke, R, Karlstrom, M, Yang, N, Leiros, I, Ladenstein, R, Birkeland, N.K, Steen, I.H. | 登録日 | 2006-06-08 | 公開日 | 2007-04-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Thermal Stability of Isocitrate Dehydrogenase from Archaeoglobus Fulgidus Studied by Crystal Structure Analysis and Engineering of Chimers Extremophiles, 11, 2007
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1XD5
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![BU of 1xd5 by Molmil](/molmil-images/mine/1xd5) | Crystal structures of novel monomeric monocot mannose-binding lectins from Gastrodia elata | 分子名称: | SULFATE ION, antifungal protein GAFP-1 | 著者 | Liu, W, Yang, N, Wang, M, Huang, R.H, Hu, Z, Wang, D.C. | 登録日 | 2004-09-04 | 公開日 | 2005-01-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Mechanism Governing the Quaternary Organization of Monocot Mannose-binding Lectin Revealed by the Novel Monomeric Structure of an Orchid Lectin J.Biol.Chem., 280, 2005
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1XD6
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![BU of 1xd6 by Molmil](/molmil-images/mine/1xd6) | Crystal structures of novel monomeric monocot mannose-binding lectins from Gastrodia elata | 分子名称: | SULFATE ION, gastrodianin-4 | 著者 | Liu, W, Yang, N, Wang, M, Huang, R.H, Hu, Z, Wang, D.C. | 登録日 | 2004-09-04 | 公開日 | 2005-01-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Mechanism Governing the Quaternary Organization of Monocot Mannose-binding Lectin Revealed by the Novel Monomeric Structure of an Orchid Lectin J.Biol.Chem., 280, 2005
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6JN2
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![BU of 6jn2 by Molmil](/molmil-images/mine/6jn2) | Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10 | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10 | 著者 | Song, X, Wang, M, Yang, N, Xu, R.M. | 登録日 | 2019-03-13 | 公開日 | 2019-09-18 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity. Proc.Natl.Acad.Sci.USA, 116, 2019
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8J72
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![BU of 8j72 by Molmil](/molmil-images/mine/8j72) | Crystal structure of mammalian Trim71 in complex with lncRNA Trincr1 | 分子名称: | E3 ubiquitin-protein ligase TRIM71, lncRNA Trincr1 | 著者 | Shi, F.D, Zhang, K, Che, S.Y, Zhi, S.X, Yang, N. | 登録日 | 2023-04-27 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Molecular mechanism governing RNA-binding property of mammalian TRIM71 protein. Sci Bull (Beijing), 69, 2024
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3UA4
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![BU of 3ua4 by Molmil](/molmil-images/mine/3ua4) | Crystal Structure of Protein Arginine Methyltransferase PRMT5 | 分子名称: | GLYCEROL, Protein arginine N-methyltransferase 5 | 著者 | Sun, L, Wang, M, Lv, Z, Yang, N, Liu, Y, Bao, S, Gong, W, Xu, R.M. | 登録日 | 2011-10-21 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | 主引用文献 | Structural insights into protein arginine symmetric dimethylation by PRMT5 Proc.Natl.Acad.Sci.USA, 108, 2011
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7CQ2
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![BU of 7cq2 by Molmil](/molmil-images/mine/7cq2) | Crystal structure of Slx1-Slx4 | 分子名称: | GLYCEROL, SLX4 isoform 1, Structure-specific endonuclease subunit SLX1, ... | 著者 | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | 登録日 | 2020-08-08 | 公開日 | 2021-06-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res., 49, 2021
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