4PW7
structure of UHRF2-SRA in complex with a 5mC-containing DNA
Summary for 4PW7
Entry DOI | 10.2210/pdb4pw7/pdb |
Related | 4PW5 4PW6 |
Descriptor | E3 ubiquitin-protein ligase UHRF2, 5mC-containing DNA1, 5mC-containing DNA2, ... (4 entities in total) |
Functional Keywords | sra, 5hmc binding, 5hmc-containing dna, methylation, nuclear, ligase-dna complex, ligase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q96PU4 |
Total number of polymer chains | 8 |
Total formula weight | 116920.56 |
Authors | |
Primary citation | Zhou, T.,Xiong, J.,Wang, M.,Yang, N.,Wong, J.,Zhu, B.,Xu, R.M. Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2. Mol.Cell, 54:879-886, 2014 Cited by PubMed: 24813944DOI: 10.1016/j.molcel.2014.04.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.001 Å) |
Structure validation
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