1UK3
| Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) At pH7.6 | 分子名称: | 3C-like proteinase | 著者 | Yang, H, Yang, M, Liu, Y, Bartlam, M, Ding, Y, Lou, Z, Sun, L, Zhou, Z, Ye, S, Anand, K, Pang, H, Gao, G.F, Hilgenfeld, R, Rao, Z. | 登録日 | 2003-08-14 | 公開日 | 2003-11-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor Proc.Natl.Acad.Sci.USA, 100, 2003
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1UK4
| Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor | 分子名称: | 3C-like proteinase nsp5, 5-mer peptide of inhibitor | 著者 | Yang, H, Yang, M, Liu, Y, Bartlam, M, Ding, Y, Lou, Z, Sun, L, Zhou, Z, Ye, S, Anand, K, Pang, H, Gao, G.F, Hilgenfeld, R, Rao, Z. | 登録日 | 2003-08-14 | 公開日 | 2003-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor Proc.Natl.Acad.Sci.USA, 100, 2003
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1XMA
| Structure of a transcriptional regulator from Clostridium thermocellum Cth-833 | 分子名称: | MERCURY (II) ION, Predicted transcriptional regulator, UNKNOWN ATOM OR ION | 著者 | Yang, H, Chen, L, Lee, D, Habel, J, Nguyen, J, Chang, S.-H, Kataeva, I, Xu, H, Chang, J, Zhao, M, Horanyi, P, Florence, Q, Zhou, W, Tempel, W, Lin, D, Praissman, J, Zhang, H, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Ljungdahl, L, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-10-01 | 公開日 | 2004-12-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structure of a transcriptional regulator from Clostridium thermocellum Cth-833 To be published
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2AMP
| Crystal Structure Of Porcine Transmissible Gastroenteritis Virus Mpro in Complex with an Inhibitor N1 | 分子名称: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | 著者 | Yang, H, Xue, X, Yang, K, Zhao, Q, Bartlam, M, Rao, Z. | 登録日 | 2005-08-10 | 公開日 | 2005-09-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3, 2005
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2AMD
| Crystal Structure Of SARS_CoV Mpro in Complex with an Inhibitor N9 | 分子名称: | 3C-like proteinase, N-(3-FUROYL)-D-VALYL-L-VALYL-N~1~-((1R,2Z)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-D-LEUCINAMIDE | 著者 | Yang, H, Xue, X, Yang, K, Zhao, Q, Bartlam, M, Rao, Z. | 登録日 | 2005-08-09 | 公開日 | 2005-09-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3, 2005
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2AMQ
| Crystal Structure Of SARS_CoV Mpro in Complex with an Inhibitor N3 | 分子名称: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | 著者 | Yang, H, Xue, X, Yang, K, Zhao, Q, Bartlam, M, Rao, Z. | 登録日 | 2005-08-10 | 公開日 | 2005-09-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3, 2005
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2D2D
| Crystal Structure Of SARS-CoV Mpro in Complex with an Inhibitor I2 | 分子名称: | 3C-like proteinase, ETHYL (2E,4S)-4-[((2R)-2-{[N-(TERT-BUTOXYCARBONYL)-L-VALYL]AMINO}-2-PHENYLETHANOYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENT-2-ENOATE | 著者 | Yang, H, Bartlam, M, Xue, X, Yang, K, Liang, W, Ding, Y, Rao, Z. | 登録日 | 2005-09-08 | 公開日 | 2005-09-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3, 2005
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1ZGH
| Methionyl-tRNA formyltransferase from Clostridium thermocellum | 分子名称: | Methionyl-tRNA formyltransferase, UNKNOWN ATOM OR ION | 著者 | Yang, H, Kataeva, I, Xu, H, Zhao, M, Chang, J, Liu, Z, Chen, L, Tempel, W, Habel, J, Zhou, W, Lee, D, Lin, D, Chang, S, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Wang, B, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2005-04-21 | 公開日 | 2005-05-03 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Methionyl-tRNA formyltransferase from Clostridium thermocellum To be published
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5GXJ
| Zika Virus NS2B-NS3 protease | 分子名称: | FLAVIVIRUS_NS2B,LINKER,Peptidase S7 | 著者 | Yang, H, Chen, X, Ji, X, Xiong, Y, Yang, K. | 登録日 | 2016-09-18 | 公開日 | 2017-05-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Viral protease activation mechanism To Be Published
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3NK6
| Structure of the Nosiheptide-resistance methyltransferase | 分子名称: | 23S rRNA methyltransferase | 著者 | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | 登録日 | 2010-06-18 | 公開日 | 2010-07-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus Biochemistry, 49, 2010
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3NK7
| Structure of the Nosiheptide-resistance methyltransferase S-adenosyl-L-methionine Complex | 分子名称: | 23S rRNA methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | 登録日 | 2010-06-18 | 公開日 | 2010-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus Biochemistry, 49, 2010
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3NFP
| Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain | 分子名称: | Heavy chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha, Light chain of Fab fragment of daclizumab | 著者 | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | 登録日 | 2010-06-10 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
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7UU5
| Crystal structure of APOBEC3G complex with 5'-Overhang dsRNA | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*AP*AP*CP*CP*GP*CP*AP*GP*CP*G)-3'), RNA (5'-R(P*UP*AP*AP*CP*GP*CP*UP*GP*CP*GP*G)-3'), ... | 著者 | Yang, H, Li, S, Chen, X.S. | 登録日 | 2022-04-28 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
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7UU4
| Crystal structure of APOBEC3G complex with ssRNA | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*AP*AP*UP*UP*U)-3'), SULFATE ION, ... | 著者 | Yang, H, Li, S, Chen, X.S. | 登録日 | 2022-04-28 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
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7UU3
| Crystal structure of APOBEC3G complex with 3'overhangs RNA-Complex | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(*CP*CP*CP*AP*CP*GP*GP*GP*AP*AP*U)-3'), RNA (5'-R(*CP*CP*CP*GP*UP*GP*GP*GP*AP*AP*U)-3'), ... | 著者 | Yang, H, Li, S, Chen, X.S. | 登録日 | 2022-04-28 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.099 Å) | 主引用文献 | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
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3NFS
| Crystal structure the Fab fragment of therapeutic antibody daclizumab | 分子名称: | Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab | 著者 | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | 登録日 | 2010-06-10 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
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6V44
| The crystal structure of hemagglutinin from swine influenza virus A/swine/Missouri/A01727926/2015 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | 著者 | Yang, H, Stevens, J. | 登録日 | 2019-11-27 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins Heliyon, 6, 2020
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6V47
| The crystal structure of hemagglutinin from A/duck/Memphis/546/1974 (H11N9) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Yang, H, Stevens, J. | 登録日 | 2019-11-27 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins Heliyon, 6, 2020
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6V48
| The crystal structure of hemagglutinin from A/mallard/Gurjev/263/1982 (H14N5) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | 著者 | Yang, H, Stevens, J. | 登録日 | 2019-11-27 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | 主引用文献 | Molecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins Heliyon, 6, 2020
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6V46
| The crystal structure of hemagglutinin from A/turkey/Ontario/6118/1968 (H8N4) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yang, H, Stevens, J. | 登録日 | 2019-11-27 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.248 Å) | 主引用文献 | Molecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins Heliyon, 6, 2020
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6V49
| The crystal structure of hemagglutinin from A/wedge-tailed shearwater/Western Australia/2576/1979 (H15N9) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | 著者 | Yang, H, Stevens, J. | 登録日 | 2019-11-27 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins Heliyon, 6, 2020
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5H64
| Cryo-EM structure of mTORC1 | 分子名称: | Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 | 著者 | Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H. | 登録日 | 2016-11-10 | 公開日 | 2017-01-25 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | 4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1 Protein Cell, 7, 2016
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1YEM
| Conserved hypothetical protein Pfu-838710-001 from Pyrococcus furiosus | 分子名称: | Conserved hypothetical protein Pfu-838710-001, PLATINUM (II) ION, UNKNOWN ATOM OR ION | 著者 | Yang, H, Chang, J, Shah, A, Ng, J.D, Liu, Z.-J, Chen, L, Lee, D, Tempel, W, Praissman, J.L, Lin, D, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Jenney Jr, F.E, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-12-28 | 公開日 | 2005-01-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Conserved hypothetical protein Pfu-838710-001 from Pyrococcus furiosus To be published
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3V9R
| Crystal structure of Saccharomyces cerevisiae MHF complex | 分子名称: | SULFATE ION, Uncharacterized protein YDL160C-A, Uncharacterized protein YOL086W-A | 著者 | Yang, H, Zhang, T, Zhong, C, Li, H, Zhou, J, Ding, J. | 登録日 | 2011-12-28 | 公開日 | 2012-02-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Saccharomyces Cerevisiae MHF Complex Structurally Resembles the Histones (H3-H4)(2) Heterotetramer and Functions as a Heterotetramer Structure, 20, 2012
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1MIU
| Structure of a BRCA2-DSS1 complex | 分子名称: | Breast Cancer type 2 susceptibility protein, Deleted in split hand/split foot protein 1, MERCURY (II) ION | 著者 | Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P. | 登録日 | 2002-08-23 | 公開日 | 2002-09-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA
structure Science, 297, 2002
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