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7JZ1
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BU of 7jz1 by Molmil
Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34
分子名称: MGC34 heavy chain, MGC34 light chain
著者Xu, K, Kwong, P.D.
登録日2020-09-01
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
6CDM
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BU of 6cdm by Molmil
Structure of vaccine-elicited HIV-1 neutralizing antibody vFP7.04 in complex with HIV-1 fusion peptide residue 512-519
分子名称: HIV fusion peptide (512-519), vFP7.04 heavy chain, vFP7.04 light chain
著者Xu, K, Liu, K, Kwong, P.D.
登録日2018-02-08
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.408 Å)
主引用文献Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
6CDO
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BU of 6cdo by Molmil
Structure of vaccine-elicited HIV-1 neutralizing antibody vFP16.02 in complex with HIV-1 fusion peptide residue 512-519
分子名称: HIV-1 fusion peptide 512-519, SULFATE ION, vFP16.02 Fab heavy chain, ...
著者Xu, K, Liu, K, Kwong, P.D.
登録日2018-02-08
公開日2018-05-16
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
6CDP
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BU of 6cdp by Molmil
Vaccine-elicited HIV-1 neutralizing antibody vFP20.01 in complex with HIV-1 fusion peptide residue 512-519
分子名称: HIV-1 fusion peptide 512-519, SULFATE ION, vFP20.01 Fab heavy chain, ...
著者Xu, K, Liu, K, Kwong, P.D.
登録日2018-02-08
公開日2018-05-16
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.456 Å)
主引用文献Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
6CMG
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BU of 6cmg by Molmil
Crystal Structure of the Hendra Virus Attachment G Glycoprotein Bound to a Potent Cross-Reactive Neutralizing Human Monoclonal Antibody m102.3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G, ...
著者Xu, K, Nikolov, D.
登録日2018-03-05
公開日2018-04-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.
PLoS Pathog., 9, 2013
6CMI
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BU of 6cmi by Molmil
Crystal Structure of the Hendra Virus Attachment G Glycoprotein Bound to a Potent Cross-Reactive Neutralizing Human Monoclonal Antibody m102.3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G, ...
著者Xu, K, Nikolov, D.
登録日2018-03-05
公開日2018-04-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.
PLoS Pathog., 9, 2013
5ED0
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BU of 5ed0 by Molmil
Structure of the Shigella flexneri VapC mutant D7N
分子名称: tRNA(fMet)-specific endonuclease VapC
著者Xu, K, Dedic, E, Brodersen, D.E.
登録日2015-10-20
公開日2016-02-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
5ECY
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BU of 5ecy by Molmil
Structure of the Shigella flexneri VapC mutant D98N crystal form 2
分子名称: tRNA(fMet)-specific endonuclease VapC
著者Xu, K, Dedic, E, Brodersen, D.E.
登録日2015-10-20
公開日2016-10-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis on the active site architecture of an activated VapC toxin from Shigella flexneri
to be published
5EVM
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BU of 5evm by Molmil
Crystal Structure of Nipah Virus Fusion Glycoprotein in the Prefusion State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MALONATE ION, ...
著者Xu, K, Nikolov, D.B.
登録日2015-11-20
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.367 Å)
主引用文献Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly.
Plos Pathog., 11, 2015
5ECW
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BU of 5ecw by Molmil
Structure of the Shigella flexneri VapC mutant D7A
分子名称: tRNA(fMet)-specific endonuclease VapC
著者Xu, K, Dedic, E, Brodersen, D.E.
登録日2015-10-20
公開日2016-02-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
5ECD
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BU of 5ecd by Molmil
Structure of the Shigella flexneri VapC mutant D98N crystal form 1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, tRNA(fMet)-specific endonuclease VapC
著者Xu, K.
登録日2015-10-20
公開日2016-02-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
3D11
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BU of 3d11 by Molmil
Crystal Structures of the Nipah G Attachment Glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase, ...
著者Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B.
登録日2008-05-02
公開日2008-08-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Proc.Natl.Acad.Sci.USA, 105, 2008
3D12
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BU of 3d12 by Molmil
Crystal Structures of Nipah Virus G Attachment Glycoprotein in Complex with its Receptor Ephrin-B3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-B3, ...
著者Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B.
登録日2008-05-02
公開日2008-08-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Proc.Natl.Acad.Sci.USA, 105, 2008
7XOT
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BU of 7xot by Molmil
Crystal structure of Keap1_6k
分子名称: 2-[[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]-[4-(2-diethoxyphosphorylethanoylamino)phenyl]sulfonyl-amino]ethanamide, Kelch-like ECH-associated protein 1
著者Xu, K.
登録日2022-05-01
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Keap1_6k
To Be Published
6WWC
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BU of 6wwc by Molmil
Vaccine-elicited mouse FP-targeting neutralizing antibody vFP16.02 with S48K mutation in light chain in complex with HIV fusion peptide (residue 512-519)
分子名称: fusion peptide, vFP16.02 antibody heavy chain, vFP16.02 antibody light chain
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2020-05-09
公開日2021-02-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.563 Å)
主引用文献Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 118, 2021
6WX2
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BU of 6wx2 by Molmil
Vaccine-elicited mouse FP-targeting neutralizing antibody vFP16.02 with F60P mutation on light chain in complex with HIV fusion peptide (residue 512-519)
分子名称: fusion peptide, vFP16.02 antibody heavy chain, vFP16.02 antibody light chain
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2020-05-09
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MY2
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BU of 7my2 by Molmil
CryoEM structure of neutralizing nanobody Nb30 in complex with SARS-CoV2 spike
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb30, ...
著者Xu, K, Kwong, P.D.
登録日2021-05-20
公開日2021-06-16
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.
Nature, 595, 2021
7MY3
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BU of 7my3 by Molmil
CryoEM structure of neutralizing nanobody Nb12 in complex with SARS-CoV2 spike
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb12, ...
著者Xu, K, Kwong, P.D.
登録日2021-05-20
公開日2021-06-16
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.
Nature, 595, 2021
7RDA
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BU of 7rda by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.138
分子名称: Circumsporozoite protein, antibody m43.138 heavy chain, antibody m43.138 light chain
著者Xu, K, Kwong, P.D.
登録日2021-07-09
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RD9
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BU of 7rd9 by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.159
分子名称: Circumsporozoite protein, antibody m43.159 heavy chain, antibody m43.159 light chain
著者Xu, K, Kwong, P.D.
登録日2021-07-09
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RD3
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BU of 7rd3 by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.126
分子名称: Circumsporozoite protein, antibody m42.126 heavy chain, antibody m42.126 light chain
著者Xu, K, Kwong, P.D.
登録日2021-07-09
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RCS
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BU of 7rcs by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.160
分子名称: Circumsporozoite protein, antibody m43.160 heavy chain, antibody m43.160 light chain
著者Xu, K, Kwong, P.D.
登録日2021-07-08
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RD4
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BU of 7rd4 by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.149
分子名称: Circumsporozoite protein, antibody m43.149 heavy chain, antibody m43.149 light chain
著者Xu, K, Kwong, P.D.
登録日2021-07-09
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
8ELI
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BU of 8eli by Molmil
Broadly neutralizing antibody VRC34-combo.1 in complex with HIV fusion peptide (residue 512-519)
分子名称: Fusion peptide, VRC34-combo.1 Fab Heavy chain, VRC34-combo.1 Fab Light chain
著者Xu, K, Kwong, P.D.
登録日2022-09-24
公開日2023-09-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.
Nat Commun, 14, 2023
5L0Q
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BU of 5l0q by Molmil
Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Disintegrin and metalloproteinase domain-containing protein 10, MAGNESIUM ION, ...
著者Xu, K, Saha, N, Nikolov, D.B.
登録日2016-07-28
公開日2016-11-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.759 Å)
主引用文献An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
J.Exp.Med., 213, 2016

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