1FX8
 
 | | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITH SUBSTRATE GLYCEROL | | 分子名称: | GLYCEROL, GLYCEROL UPTAKE FACILITATOR PROTEIN, octyl beta-D-glucopyranoside | | 著者 | Fu, D, Libson, A, Miercke, L.J.W, Weitzman, C, Nollert, P, Stroud, R.M. | | 登録日 | 2000-09-25 | | 公開日 | 2000-11-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a glycerol-conducting channel and the basis for its selectivity.
Science, 290, 2000
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1PLG
 | | EVIDENCE FOR THE EXTENDED HELICAL NATURE OF POLYSACCHARIDE EPITOPES. THE 2.8 ANGSTROMS RESOLUTION STRUCTURE AND THERMODYNAMICS OF LIGAND BINDING OF AN ANTIGEN BINDING FRAGMENT SPECIFIC FOR ALPHA-(2->8)-POLYSIALIC ACID | | 分子名称: | IGG2A=KAPPA= | | 著者 | Evans, S.V, Sigurskjold, B.W, Jennings, H.J, Brisson, J.-R, Tse, W.C, To, R, Altman, E, Frosch, M, Weisgerber, C, Kratzin, H, Klebert, S, Vaesen, M, Bitter-Suermann, D, Rose, D.R, Young, N.M, Bundle, D.R. | | 登録日 | 1995-04-24 | | 公開日 | 1996-04-03 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid.
Biochemistry, 34, 1995
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4A4V
 | | Ligand binding domain of human PPAR gamma in complex with amorfrutin 2 | | 分子名称: | AMORFRUTIN 2, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | | 著者 | de Groot, J.C, Weidner, C, Krausze, J, Kawamoto, K, Schroeder, F.C, Sauer, S, Buessow, K. | | 登録日 | 2011-10-20 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor Gamma.
J.Med.Chem., 56, 2013
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4A4W
 | | Ligand binding domain of human PPAR gamma in complex with amorfrutin B | | 分子名称: | AMORFRUTIN B, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | | 著者 | de Groot, J.C, Weidner, C, Krausze, J, Kawamoto, K, Schroeder, F.C, Sauer, S, Buessow, K. | | 登録日 | 2011-10-20 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor Gamma.
J.Med.Chem., 56, 2013
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6B5N
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6B5L
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6B5S
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6B5P
 | | Structure of PfCSP peptide 20 with human antibody CIS42 | | 分子名称: | CIS42 Fab Heavy chain, CIS42 Fab Light chain, pfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP | | 著者 | Pancera, M, Weidle, C. | | 登録日 | 2017-09-29 | | 公開日 | 2018-03-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | | 主引用文献 | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
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6B5R
 | | Structure of PfCSP peptide 21 with human antibody CIS42 | | 分子名称: | CIS42 Fab Heavy chain, CIS42 Fab Light chain, PfCSP peptide 21: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN | | 著者 | Pancera, M, Weidle, C. | | 登録日 | 2017-09-29 | | 公開日 | 2018-03-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.775 Å) | | 主引用文献 | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
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6BLA
 | | Structure of AMM01 Fab, an anti EBV gH/gL neutralizing antibody | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMM01 Fab Heavy chain, ... | | 著者 | Pancera, M, Weidle, C, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2017-11-09 | | 公開日 | 2018-04-25 | | 最終更新日 | 2019-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
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6B5M
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6B5T
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6B5O
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6C5V
 | | An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ... | | 著者 | Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2018-01-16 | | 公開日 | 2018-05-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
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7RDW
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2YFE
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6MFT
 | | Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Weidle, C, Pancera, M, Stamatatos, L, Gray, M. | | 登録日 | 2018-09-12 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.315 Å) | | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
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6J1O
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6J46
 | | LepI-SAH complex structure | | 分子名称: | O-methyltransferase lepI, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Qiu, S, Wei, C. | | 登録日 | 2019-01-08 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.621 Å) | | 主引用文献 | Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme.
Signal Transduct Target Ther, 4, 2019
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4J6I
 | | Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform | | 分子名称: | 2-methyl-1-(4-{2-[1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl]-4,5-dihydro[1]benzoxepino[5,4-d][1,3]thiazol-8-yl}-1H-pyrazol-1-yl)propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | | 著者 | Murray, J.M, Rouge, L, Wu, P. | | 登録日 | 2013-02-11 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform.
Bioorg.Med.Chem.Lett., 23, 2013
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7DEY
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3T8M
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2AYD
 | | Crystal Structure of the C-terminal WRKY domainof AtWRKY1, an SA-induced and partially NPR1-dependent transcription factor | | 分子名称: | SUCCINIC ACID, WRKY transcription factor 1, ZINC ION | | 著者 | Duan, M.R, Nan, J, Li, Y, Su, X.D. | | 登録日 | 2005-09-07 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | DNA binding mechanism revealed by high resolution crystal structure of Arabidopsis thaliana WRKY1 protein.
Nucleic Acids Res., 35, 2007
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7DZ2
 | | Crystal structures of D-allulose 3-epimerase from Sinorhizobium fredii | | 分子名称: | D-tagatose 3-epimerase, MAGNESIUM ION, SULFATE ION | | 著者 | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | | 登録日 | 2021-01-23 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
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7DZ3
 | | Crystal structures of D-allulose 3-epimerase with D-fructose from Sinorhizobium fredii | | 分子名称: | D-fructose, D-tagatose 3-epimerase, MAGNESIUM ION | | 著者 | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | | 登録日 | 2021-01-23 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
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