4Z2Z
 
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5KES
 | | Solution structure of the yeast Ddi1 HDD domain | | 分子名称: | DNA damage-inducible protein 1 | | 著者 | Trempe, J.-F, Ratcliffe, C, Veverka, V, Saskova, K, Gehring, K. | | 登録日 | 2016-06-10 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.
Sci Rep, 6, 2016
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6SGI
 | | Nek2 kinase bound to inhibitor 96 | | 分子名称: | 4-[(6-ethyl-7~{H}-purin-2-yl)amino]benzenesulfonamide, CHLORIDE ION, Serine/threonine-protein kinase Nek2 | | 著者 | Richards, M.W, Mas-Droux, C.P, Bayliss, R. | | 登録日 | 2019-08-05 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | 2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase.
Rsc Med Chem, 11, 2020
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6SGH
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1G0Z
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5J5T
 | | GLK co-crystal structure with aminopyrrolopyrimidine inhibitor | | 分子名称: | 5-[2-(piperidin-4-yl)-1,3-thiazol-5-yl]-3-[(pyridin-4-yl)methoxy]pyridin-2-amine, Mitogen-activated protein kinase kinase kinase kinase 3 | | 著者 | Silvian, L.F, Marcotte, D. | | 登録日 | 2016-04-03 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension.
Protein Sci., 26, 2017
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1BIY
 | | STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN | | 分子名称: | CARBONATE ION, FE (III) ION, LACTOFERRIN | | 著者 | Karthikeyan, S, Yadav, S, Singh, T.P. | | 登録日 | 1998-06-21 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | | 主引用文献 | Structure of buffalo lactoferrin at 3.3 A resolution at 277 K.
Acta Crystallogr.,Sect.D, 56, 2000
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5KO1
 | | Pseudokinase Domain of MLKL bound to Compound 4. | | 分子名称: | Mixed lineage kinase domain-like protein, [(1~{R})-2-[(4-fluorophenyl)amino]-2-oxidanylidene-1-phenyl-ethyl] 3-azanylpyrazine-2-carboxylate | | 著者 | Marcotte, D.J. | | 登録日 | 2016-06-29 | | 公開日 | 2016-11-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis.
Plos One, 11, 2016
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5KNJ
 | | Pseudokinase Domain of MLKL bound to Compound 1. | | 分子名称: | 1-[4-[methyl-[2-[(3-sulfamoylphenyl)amino]pyrimidin-4-yl]amino]phenyl]-3-[4-(trifluoromethyloxy)phenyl]urea, Mixed lineage kinase domain-like protein | | 著者 | Marcotte, D.J. | | 登録日 | 2016-06-28 | | 公開日 | 2016-11-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis.
Plos One, 11, 2016
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6SGK
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6SGD
 | | Nek2 kinase covalently bound to 2-arylamino-6-ethynylpurine inhibitor 24 | | 分子名称: | 4-[(6-ethenyl-7~{H}-purin-2-yl)amino]benzenesulfonamide, CHLORIDE ION, SODIUM ION, ... | | 著者 | Richards, M.W, Mas-Droux, C.P, Bayliss, R. | | 登録日 | 2019-08-04 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase.
Rsc Med Chem, 11, 2020
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1B1X
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5M55
 | | Nek2 bound to arylaminopurine 71 | | 分子名称: | 6-[(~{Z})-2-(diethylamino)ethenyl]-~{N}-phenyl-7~{H}-purin-2-amine, CHLORIDE ION, SULFATE ION, ... | | 著者 | Bayliss, R. | | 登録日 | 2016-10-20 | | 公開日 | 2016-11-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
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5M51
 | | Nek2 bound to arylaminopurine compound 8 | | 分子名称: | 3-[[6-(cyclohexylmethoxy)-9~{H}-purin-2-yl]amino]benzamide, Serine/threonine-protein kinase Nek2 | | 著者 | Bayliss, R, Yeoh, S. | | 登録日 | 2016-10-20 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | | 主引用文献 | Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
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5M53
 | | Nek2 bound to arylaminopurine inhibitor 11 | | 分子名称: | 1,2-ETHANEDIOL, 3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N},~{N}-dimethyl-benzamide, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Bayliss, R, Carr, K.H. | | 登録日 | 2016-10-20 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
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5M57
 | | Nek2 bound to arylaminopurine 6 | | 分子名称: | O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE, Serine/threonine-protein kinase Nek2 | | 著者 | Bayliss, R. | | 登録日 | 2016-10-20 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
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5XEP
 | | Crystal structure of BRP39, a chitinase-like protein, at 2.6 Angstorm resolution | | 分子名称: | 1,2-ETHANEDIOL, Chitinase-3-like protein 1 | | 著者 | Mohanty, A.K, Fisher, A.J, Choudhary, S, Kaushik, J.K. | | 登録日 | 2017-04-05 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of BRP39, a signalling glycoprotein expressed during mammary gland apoptosis.
To be published
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1PC8
 | | Crystal Structure of a novel form of mistletoe lectin from Himalayan Viscum album L. at 3.8A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Himalayan mistletoe ribosome-inactivating protein, ... | | 著者 | Mishra, V, Ethayathulla, A.S, Paramasivam, M, Singh, G, Yadav, S, Kaur, P, Sharma, R.S, Babu, C.R, Singh, T.P. | | 登録日 | 2003-05-16 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structure of a novel ribosome-inactivating protein from a hemi-parasitic plant inhabiting the northwestern Himalayas.
Acta Crystallogr.,Sect.D, 60, 2004
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