7CVY
 
 | | Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124 | | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | | 登録日 | 2020-08-27 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
3EVP
 | | crystal structure of circular-permutated EGFP | | 分子名称: | Green fluorescent protein,Green fluorescent protein | | 著者 | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | | 登録日 | 2008-10-13 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.453 Å) | | 主引用文献 | Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
|
|
3EVR
 | | Crystal structure of Calcium bound monomeric GCAMP2 | | 分子名称: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | 著者 | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | | 登録日 | 2008-10-13 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
|
|
3EVU
 | | Crystal structure of Calcium bound dimeric GCAMP2 | | 分子名称: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | 著者 | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | | 登録日 | 2008-10-13 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
|
|
3EVV
 | | Crystal Structure of Calcium bound dimeric GCAMP2 (#2) | | 分子名称: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | 著者 | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | | 登録日 | 2008-10-13 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
|
|
5CGA
 | | Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with substrate analog 2-(1,3,5-trimethyl-1H-pyrazole-4-yl)ethanol | | 分子名称: | 2-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethanol, Hydroxyethylthiazole kinase, MAGNESIUM ION | | 著者 | Kuenz, M, Drebes, J, Windshuegel, B, Cang, H, Wrenger, C, Betzel, C. | | 登録日 | 2015-07-09 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
|
|
5CGE
 | | Structure of Hydroxyethylthiazole Kinase ThiM from Staphylococcus aureus in complex with substrate analog 2-(2-methyl-1H-imidazole-1-yl)ethanol | | 分子名称: | 2-(2-methyl-1H-imidazol-1-yl)ethanol, Hydroxyethylthiazole kinase, MAGNESIUM ION | | 著者 | Kuenz, M, Drebes, J, Windshuegel, B, Cang, H, Wrenger, C, Betzel, C. | | 登録日 | 2015-07-09 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
|
|
6T2B
 | | Glycoside hydrolase family 109 from Akkermansia muciniphila in complex with GalNAc and NAD+. | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Glycosyl hydrolase family 109 protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Chaberski, E.K, Fredslund, F, Teze, D, Shuoker, B, Kunstmann, S, Karlsson, E.N, Hachem, M.A, Welner, D.H. | | 登録日 | 2019-10-08 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | The Catalytic Acid-Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable alpha-Retaining and beta-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia muciniphila
Acs Catalysis, 2020
|
|
8AYR
 | | Sialidases and Fucosidases of Akkermansia muciniphila are key for rapid growth on colonic mucin and nutrient sharing amongst mucin-associated human gut microbiota | | 分子名称: | CALCIUM ION, Coagulation factor 5/8 type domain protein | | 著者 | Sakanaka, H, Nielsen, T.S, Pichler, M.J, Nordberg Karlsson, E, Abou Hachem, M, Morth, J.P. | | 登録日 | 2022-09-02 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.
Nat Commun, 14, 2023
|
|
8AXT
 | | Sialidases and Fucosidases of Akkermansia muciniphila are key for rapid growth on colonic mucin and nutrient sharing amongst mucin-associated human gut microbiota | | 分子名称: | CALCIUM ION, CHLORIDE ION, Sialidase domain-containing protein | | 著者 | Sakanaka, H, Nielsen, T.S, Pichler, M.J, Nordberg Karlsson, E, Abou Hachem, M, Morth, J.P. | | 登録日 | 2022-08-31 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.
Nat Commun, 14, 2023
|
|
8AXS
 | | Sialidases and Fucosidases of Akkermansia muciniphila are key for rapid growth on colonic mucin and nutrient sharing amongst mucin-associated human gut microbiota | | 分子名称: | 1,2-ETHANEDIOL, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CALCIUM ION, ... | | 著者 | Sakanaka, H, Nielsen, T.S, Pichler, M.J, Nordberg Karlsson, E, Abou Hachem, M, Morth, J.P. | | 登録日 | 2022-08-31 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.
Nat Commun, 14, 2023
|
|
8AXI
 | | Sialidases and Fucosidases of Akkermansia muciniphila are key for rapid growth on colonic mucin and nutrient sharing amongst mucin-associated human gut microbiota | | 分子名称: | 1,2-ETHANEDIOL, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CALCIUM ION, ... | | 著者 | Sakanaka, H, Nielsen, T.S, Pichler, M.J, Nordberg Karlsson, E, Abou Hachem, M, Morth, J.P. | | 登録日 | 2022-08-31 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.
Nat Commun, 14, 2023
|
|
3RWT
 | |
3RWA
 | |
8DV6
 | | Zika virus envelope protein structure in complex with a potent Human mAb | | 分子名称: | Envelope protein E, mAb Fab Heavy Chain, mAb Fab Light Chain | | 著者 | Cameron, A, Puhl, A.C, deSilva, A.M, Premkumar, L. | | 登録日 | 2022-07-28 | | 公開日 | 2023-01-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.
Plos Pathog., 19, 2023
|
|
6LSH
 | | Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6M form) | | 分子名称: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... | | 著者 | Li, R, Wang, M, Jing, X, Gong, P. | | 登録日 | 2020-01-17 | | 公開日 | 2020-04-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.231 Å) | | 主引用文献 | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
|
|
6LSG
 | | Crystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form) | | 分子名称: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... | | 著者 | Li, R, Wang, M, Jing, X, Gong, P. | | 登録日 | 2020-01-17 | | 公開日 | 2020-04-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
|
|
6WS4
 | | Crystal structure of KRAS-G12D/K104Q mutant, GDP-bound | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Tran, T.H, Simanshu, D.K. | | 登録日 | 2020-04-30 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Allosteric regulation of switch-II domain controls KRAS oncogenicity.
Cancer Res., 2023
|
|
6WS2
 | |
8STN
 | | Crystal structure of KRAS-G12D/G75A mutant, GDP-bound | | 分子名称: | CHLORIDE ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Tran, T.H, Dharmaiah, S, Simanshu, D.K. | | 登録日 | 2023-05-10 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
Cancer Res., 83, 2023
|
|
8STM
 | | Crystal structure of KRAS-G75A mutant, GDP-bound | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Tran, T.H, Dharmaiah, S, Simanshu, D.K. | | 登録日 | 2023-05-10 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
Cancer Res., 83, 2023
|
|
6KQT
 | | Crystal Structure of GH136 lacto-N-biosidase from Eubacterium ramulus - native protein | | 分子名称: | SODIUM ION, TRIETHYLENE GLYCOL, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yamada, C, Arakawa, T, Pichler, M.J, Abou Hachem, M, Fushinobu, S. | | 登録日 | 2019-08-18 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways.
Nat Commun, 11, 2020
|
|
6KQS
 | | Crystal Structure of GH136 lacto-N-biosidase from Eubacterium ramulus - selenomethionine derivative | | 分子名称: | GLYCEROL, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, lacto-N-biosidase | | 著者 | Yamada, C, Arakawa, T, Pichler, M.J, Abou Hachem, M, Fushinobu, S. | | 登録日 | 2019-08-18 | | 公開日 | 2020-06-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways.
Nat Commun, 11, 2020
|
|
5COJ
 | | Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol. | | 分子名称: | 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, Hydroxyethylthiazole kinase, MAGNESIUM ION | | 著者 | Drebes, J, Kuenz, M, Eberle, R.J, Oberthuer, D, Cang, H, Wrenger, C, Betzel, C. | | 登録日 | 2015-07-20 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
|
|
5CM5
 | | Structure of Hydroxyethylthiazole Kinase ThiM from Staphylococcus aureus | | 分子名称: | Hydroxyethylthiazole kinase | | 著者 | Drebes, J, Kuenz, M, Eberle, R.J, Oberthuer, D, Cang, H, Wrenger, C, Betzel, C. | | 登録日 | 2015-07-16 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
|
|
