8AXT

Sialidases and Fucosidases of Akkermansia muciniphila are key for rapid growth on colonic mucin and nutrient sharing amongst mucin-associated human gut microbiota

Summary for 8AXT

Entry DOI	10.2210/pdb8axt/pdb
Descriptor	Sialidase domain-containing protein, CALCIUM ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	sialidase, neuraminidase, hydrolase
Biological source	Akkermansia muciniphila
Total number of polymer chains	2
Total formula weight	130556.24
Authors	Sakanaka, H.,Nielsen, T.S.,Pichler, M.J.,Nordberg Karlsson, E.,Abou Hachem, M.,Morth, J.P. (deposition date: 2022-08-31, release date: 2023-03-01, Last modification date: 2024-05-01)
Primary citation	Shuoker, B.,Pichler, M.J.,Jin, C.,Sakanaka, H.,Wu, H.,Gascuena, A.M.,Liu, J.,Nielsen, T.S.,Holgersson, J.,Nordberg Karlsson, E.,Juge, N.,Meier, S.,Morth, J.P.,Karlsson, N.G.,Abou Hachem, M. Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria. Nat Commun, 14:1833-1833, 2023 Cited by PubMed: 37005422 DOI: 10.1038/s41467-023-37533-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation