7PG2
 
 | | Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin, conf 1 | | 分子名称: | Insulin, Isoform Short of Insulin receptor | | 著者 | Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P. | | 登録日 | 2021-08-12 | | 公開日 | 2022-02-02 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
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7PG4
 | | Low resolution Cryo-EM structure of the full-length insulin receptor bound to 2 insulin, conf 3 | | 分子名称: | Insulin, Isoform Short of Insulin receptor | | 著者 | Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P. | | 登録日 | 2021-08-12 | | 公開日 | 2022-02-02 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
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7PG3
 | | Low resolution Cryo-EM structure of the full-length insulin receptor bound to 3 insulin, conf 2 | | 分子名称: | Insulin, Isoform Short of Insulin receptor | | 著者 | Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P. | | 登録日 | 2021-08-12 | | 公開日 | 2022-02-02 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | | 主引用文献 | Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
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8PI5
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8PI4
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8PI6
 | | Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension | | 分子名称: | Insulin B chain,Insulin A chain | | 著者 | Johansson, E, Schluckebier, G. | | 登録日 | 2023-06-21 | | 公開日 | 2023-11-08 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
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4AJZ
 | | Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | | 分子名称: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | | 著者 | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | | 登録日 | 2012-02-21 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
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4AKJ
 | | Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | | 分子名称: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | | 著者 | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | | 登録日 | 2012-02-23 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
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4CBP
 | | Crystal structure of neural ectodermal development factor IMP-L2. | | 分子名称: | GLYCEROL, NEURAL/ECTODERMAL DEVELOPMENT FACTOR IMP-L2 | | 著者 | Kulahin, N, Kristensen, O, Brzozowski, M, Schluckebier, G, Meyts, P.D. | | 登録日 | 2013-10-15 | | 公開日 | 2014-10-29 | | 最終更新日 | 2019-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Analysis of Imp-L2 Function
To be Published
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4AK0
 | | Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | | 分子名称: | INSULIN A CHAIN, INSULIN B CHAIN | | 著者 | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | | 登録日 | 2012-02-21 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
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4AJX
 | | Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | | 分子名称: | IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ... | | 著者 | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | | 登録日 | 2012-02-20 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
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2OLY
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2OM1
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2OMH
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2OMI
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2OMG
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2OLZ
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2OM0
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2VJZ
 | | Crystal structure form ultalente insulin microcrystals | | 分子名称: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | | 著者 | Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. | | 登録日 | 2007-12-14 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Ultralente-A Microcrystalline Insulin Suspension.
Proteins, 74, 2009
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2IH4
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1TRQ
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2IBS
 | | Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position | | 分子名称: | 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... | | 著者 | Pljevaljcic, G, Lenz, T, Scheidig, A.J, Weinhold, E. | | 登録日 | 2006-09-12 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence
J.Am.Chem.Soc., 129, 2007
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2IBT
 | | Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position | | 分子名称: | 5'-D(*GP*AP*CP*AP*(3DR)P*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... | | 著者 | Lenz, T, Scheidig, A.J, Weinhold, E. | | 登録日 | 2006-09-12 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence
J.Am.Chem.Soc., 129, 2007
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1G38
 | | ADENINE-SPECIFIC METHYLTRANSFERASE M. TAQ I/DNA COMPLEX | | 分子名称: | 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... | | 著者 | Goedecke, K, Pignot, M, Goody, R.S, Scheidig, A.J, Weinhold, E. | | 登録日 | 2000-10-23 | | 公開日 | 2001-03-05 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog.
Nat.Struct.Biol., 8, 2001
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2IH2
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