6CDX
| High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin | 分子名称: | cystine knot (fluoropropylated) | 著者 | Kimura, R, Nix, J, Bongura, C, Chakraborti, S, Gambhir, S, Filipp, F.V. | 登録日 | 2018-02-09 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Evaluation of integrin alpha v beta6cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis. Nat Commun, 10, 2019
|
|
7LUK
| CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS-RORGT(244-487)-L6-SRC1(678-692) IN COMPLEX WITH AN AZATRICYCLIC RORGT INVERSE AGONIST | 分子名称: | (2S)-N-[(6aS,7R,9aS)-9a-[(4-fluorophenyl)sulfonyl]-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6,6a,7,8,9,9a-hexahydro-5H-cyclopenta[f]quinolin-7-yl]-2-hydroxy-2-methyl-3-(methylsulfonyl)propanamide, Nuclear receptor ROR-gamma | 著者 | Sack, J.S. | 登録日 | 2021-02-22 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.087 Å) | 主引用文献 | Azatricyclic Inverse Agonists of ROR gamma t That Demonstrate Efficacy in Models of Rheumatoid Arthritis and Psoriasis. Acs Med.Chem.Lett., 12, 2021
|
|
6Z7N
| |
7JH5
| Co-LOCKR: de novo designed protein switch | 分子名称: | Co-LOCKR: de novo designed protein switch | 著者 | Bick, M.J, Lajoie, M.J, Boyken, S.E, Sankaran, B, Baker, D. | 登録日 | 2020-07-20 | 公開日 | 2020-09-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | Designed protein logic to target cells with precise combinations of surface antigens. Science, 369, 2020
|
|
6Z7Q
| |
5IF4
| Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) inhibitors using Structure-Based Design | 分子名称: | 4-{8-chloro-11-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-1-oxo-7-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4,5-dihydro-1H-[1,4]diazepino[1,2-a]indol-2(3H)-yl}-1-methyl-1H-indole-6-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | 著者 | Zhao, B. | 登録日 | 2016-02-25 | 公開日 | 2017-01-18 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.392 Å) | 主引用文献 | Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors. FEBS Lett., 591, 2017
|
|
4XL8
| Crystal Structure of Human Adenovirus 52 Short Fiber Knob in Complex with 2-O-Methyl-5-N-Acetylneuraminic Acid | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, ... | 著者 | Stehle, T, Liaci, A.M. | 登録日 | 2015-01-13 | 公開日 | 2015-01-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells. Plos Pathog., 11, 2015
|
|
1B2K
| Structural effects of monovalent anions on polymorphic lysozyme crystals | 分子名称: | IODIDE ION, PROTEIN (LYSOZYME) | 著者 | Vaney, M.C, Broutin, I, Ries-Kautt, M, Ducruix, A. | 登録日 | 1998-11-26 | 公開日 | 1998-12-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural effects of monovalent anions on polymorphic lysozyme crystals. Acta Crystallogr.,Sect.D, 57, 2001
|
|
2N0X
| Three dimensional structure of EPI-X4, a human albumin-derived peptide that regulates innate immunity through the CXCR4/CXCL12 chemotactic axis and antagonizes HIV-1 entry | 分子名称: | Serum albumin | 著者 | Perez-Castells, J, Canales, A, Jimenez-Barbero, J, Gimenez-Gallego, G. | 登録日 | 2015-03-18 | 公開日 | 2015-04-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery and characterization of an endogenous CXCR4 antagonist. Cell Rep, 11, 2015
|
|
5IEZ
| |
6NE5
| |
8GLB
| Selenomethionine Derivatized Citrate Synthase (CitA) in Mycobacterium tuberculosis with Pyruvate | 分子名称: | 1,2-ETHANEDIOL, PYRUVIC ACID, citrate synthase | 著者 | Pathirage, R, Ronning, D, Favrot, L. | 登録日 | 2023-03-21 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
|
|
8GMI
| |
8GMK
| Pyruvate bound structure of Citrate Synthase (CitA) in Mycobacterium Tuberculosis | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRUVIC ACID, ... | 著者 | Pathirage, R, Ronning, D, Yamsek, M. | 登録日 | 2023-03-26 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
|
|
8GI7
| |
8GM9
| Structure of Citrate Synthase(CitA) in Mycobacterium Tuberculosis | 分子名称: | 1,2-ETHANEDIOL, ACRYLIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Pathirage, R, Ronning, D, Favrot, L. | 登録日 | 2023-03-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
|
|
8GIW
| |
8GLL
| R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Pathirage, R, Ronning, D, Petit, C. | 登録日 | 2023-03-22 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
|
|
8GMF
| |
6I2G
| |
6WNO
| |
6WTV
| |
6WOZ
| |
6WTY
| |
6WM9
| |