1B54
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![BU of 1b54 by Molmil](/molmil-images/mine/1b54) | CRYSTAL STRUCTURE OF A YEAST HYPOTHETICAL PROTEIN-A STRUCTURE FROM BNL'S HUMAN PROTEOME PROJECT | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, YEAST HYPOTHETICAL PROTEIN | 著者 | Swaminathan, S, Eswaramoorthy, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 1999-01-12 | 公開日 | 1999-01-27 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of a yeast hypothetical protein selected by a structural genomics approach. Acta Crystallogr.,Sect.D, 59, 2003
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1G0Z
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1I4X
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5XVQ
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![BU of 5xvq by Molmil](/molmil-images/mine/5xvq) | Crystal structure of monkey Nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl Nicotinamide (MNA) | 分子名称: | 3-carbamoyl-1-methylpyridin-1-ium, GLYCEROL, Nicotinamide N-methyltransferase (NNMT), ... | 著者 | Birudukota, S, Swaminathan, S, Thakur, M.K, Parveen, R, Kandan, S, Kannt, A, Gosu, R. | 登録日 | 2017-06-28 | 公開日 | 2017-08-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide Biochem. Biophys. Res. Commun., 491, 2017
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5YJF
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![BU of 5yjf by Molmil](/molmil-images/mine/5yjf) | Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with small molecule analog of Nicotinamide | 分子名称: | 6-methoxy-1-methyl-2H-pyridine-3-carboxamide, Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Swaminathan, S, Birudukota, S, Thakur, M.K, Parveen, R, Kandan, S, Hallur, M.S, Rajagopal, S, Ruf, S, Dhakshinamoorthy, S, Kannt, A, Gosu, R. | 登録日 | 2017-10-10 | 公開日 | 2018-03-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep, 8, 2018
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7EU5
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![BU of 7eu5 by Molmil](/molmil-images/mine/7eu5) | Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with tricyclic small molecule inhibitor JBSNF-000107 | 分子名称: | 6-fluoranyl-10-methyl-1,10-diazatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-11-imine, Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Swaminathan, S, Gosu, R, Birudukota, S, Kandan, S, Vaithilingam, K. | 登録日 | 2021-05-16 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.731 Å) | 主引用文献 | Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep, 12, 2022
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7ET7
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![BU of 7et7 by Molmil](/molmil-images/mine/7et7) | Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with tricyclic small molecule inhibitor JBSNF-000028 | 分子名称: | 10-methyl-1,10-diazatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-11-imine, Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Swaminathan, S, Gosu, R, Birudukota, S, Kandan, S, Vaithilingam, K. | 登録日 | 2021-05-12 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep, 12, 2022
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4LIZ
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2RHB
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![BU of 2rhb by Molmil](/molmil-images/mine/2rhb) | Crystal structure of Nsp15-H234A mutant- Hexamer in asymmetric unit | 分子名称: | Uridylate-specific endoribonuclease | 著者 | Palaninathan, S, Bhardwaj, K, Alcantara, J.M.O, Guarino, L, Yi, L.L, Kao, C.C, Sacchettini, J. | 登録日 | 2007-10-08 | 公開日 | 2007-11-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15. J.Biol.Chem., 283, 2008
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5W5A
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![BU of 5w5a by Molmil](/molmil-images/mine/5w5a) | Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c) | 分子名称: | CHLORIDE ION, HTH-type transcriptional regulator Cmr, SULFATE ION | 著者 | Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A. | 登録日 | 2017-06-14 | 公開日 | 2017-12-13 | 最終更新日 | 2019-01-09 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria. Nucleic Acids Res., 46, 2018
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5W5B
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![BU of 5w5b by Molmil](/molmil-images/mine/5w5b) | Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c), truncated construct | 分子名称: | CHLORIDE ION, HTH-type transcriptional regulator Cmr | 著者 | Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A. | 登録日 | 2017-06-14 | 公開日 | 2017-12-13 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria. Nucleic Acids Res., 46, 2018
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2ETF
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2EUI
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3HKF
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![BU of 3hkf by Molmil](/molmil-images/mine/3hkf) | Murine unglycosylated IgG Fc fragment | 分子名称: | CHLORIDE ION, Igh protein, MAGNESIUM ION | 著者 | Feige, M.J, Nath, S, Catharino, S.R, Weinfurtner, D, Steinbacher, S, Buchner, J. | 登録日 | 2009-05-23 | 公開日 | 2009-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the murine unglycosylated IgG1 Fc fragment J.Mol.Biol., 391, 2009
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6KRB
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![BU of 6krb by Molmil](/molmil-images/mine/6krb) | High resolution crystal structure of an Acylphosphatase protein cage | 分子名称: | Acylphosphatase, GLYCEROL, SULFATE ION | 著者 | Chatterjee, S, Nath, S, Sen, U. | 登録日 | 2019-08-21 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.375 Å) | 主引用文献 | High resolution structure of Vibrio cholerae acylphosphatase (VcAcP) cage: Identification of drugs, location of its binding site and engineering to facilitate cage formation. Biochem.Biophys.Res.Commun., 523, 2020
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4DVD
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3RX6
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![BU of 3rx6 by Molmil](/molmil-images/mine/3rx6) | Crystal structure of Polarity Suppression protein from Enterobacteria phage P4 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IODIDE ION, MERCURY (II) ION, ... | 著者 | Banerjee, R, Nath, S, Khamrui, S, Sen, R, Sen, U. | 登録日 | 2011-05-10 | 公開日 | 2012-07-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.039 Å) | 主引用文献 | The first structure of polarity suppression protein, Psu from enterobacteria phage P4, reveals a novel fold and a knotted dimer J.Biol.Chem., 287, 2012
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5YGG
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![BU of 5ygg by Molmil](/molmil-images/mine/5ygg) | Crystal structure of Fructokinase Double-Mutant (T261C-H108C) from Vibrio cholerae O395 in fructose, ADP and potassium ion bound form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Fructokinase, ... | 著者 | Chatterjee, S, Paul, R, Nath, S, Sen, U. | 登録日 | 2017-09-22 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.671 Å) | 主引用文献 | Large-scale conformational changes and redistribution of surface negative charge upon sugar binding dictate the fidelity of phosphorylation in Vibrio cholerae fructokinase. Sci Rep, 8, 2018
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5Z3M
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![BU of 5z3m by Molmil](/molmil-images/mine/5z3m) | Crystal structure of Low Molecular Weight Phosphotyrosine phosphatase (VcLMWPTP-2) from Vibrio choleraeO395 | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, Phosphotyrosine protein phosphatase, ... | 著者 | Chatterjee, S, Nath, S, Sen, U. | 登録日 | 2018-01-08 | 公開日 | 2018-09-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Vibrio cholerae LMWPTP-2 display unique surface charge and grooves around the active site: Indicative of distinctive substrate specificity and scope to design specific inhibitor. Biochim Biophys Acta Proteins Proteom, 1867, 2019
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5F11
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5EYN
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![BU of 5eyn by Molmil](/molmil-images/mine/5eyn) | Crystal structure of Fructokinase from Vibrio cholerae O395 in fructose, ADP, Beryllium trifluoride and calcium ion bound form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... | 著者 | Paul, R, Nath, S, Sen, U. | 登録日 | 2015-11-25 | 公開日 | 2016-11-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.289 Å) | 主引用文献 | Crystal structure of Fructokinase from Vibrio cholerae O395 in apo form To Be Published
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5F0Z
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5EY7
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1VQW
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![BU of 1vqw by Molmil](/molmil-images/mine/1vqw) | Crystal structure of a protein with similarity to flavin-containing monooxygenases and to mammalian dimethylalanine monooxygenases | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN WITH SIMILARITY TO FLAVIN-CONTAINING MONOOXYGENASES AND TO MAMMALIAN DIMETHYLALANINE MONOOXYGENASES | 著者 | Eswaramoorthy, S, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2005-01-05 | 公開日 | 2005-01-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanism of action of a flavin-containing monooxygenase. Proc.Natl.Acad.Sci.Usa, 103, 2006
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4FGS
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![BU of 4fgs by Molmil](/molmil-images/mine/4fgs) | Crystal structure of a probable dehydrogenase protein | 分子名称: | Probable dehydrogenase protein, SULFATE ION | 著者 | Eswaramoorthy, S, Rice, S, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2012-06-04 | 公開日 | 2012-08-15 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal structure of a probable dehydrogenase protein To be Published
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