5M50
| Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins | 分子名称: | Calmodulin-regulated spectrin-associated protein 3, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Akhmanova, A, Moores, C.A, Baldus, M, Steinmetz, M.O, Topf, M, Roberts, A.J, Grant, B.J, Scarabelli, G, Joseph, A.-P, van Hooff, J.J.E, Houben, K, Hua, S, Luo, Y, Stangier, M.M, Jiang, K, Atherton, J. | 登録日 | 2016-10-20 | 公開日 | 2017-10-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nat. Struct. Mol. Biol., 24, 2017
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5M5N
| Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations. | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | 著者 | Goulet, A, Moores, C.A, Cross, R.A. | 登録日 | 2016-10-22 | 公開日 | 2016-11-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | 主引用文献 | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5L
| Pseudo-atomic model of microtubule-bound S. pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | 著者 | Goulet, A, Moores, C.A, Cross, R.A. | 登録日 | 2016-10-21 | 公開日 | 2016-11-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | 主引用文献 | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5I
| Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus conformation allows formation of a cover neck bundle. | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | 著者 | Goulet, A, Moores, C.A, Cross, R.A. | 登録日 | 2016-10-21 | 公開日 | 2016-11-30 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | 主引用文献 | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5O
| Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations. | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | 著者 | Goulet, A, Moores, C.A, Cross, R.A. | 登録日 | 2016-10-22 | 公開日 | 2016-11-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | 主引用文献 | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5M
| Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations. | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | 著者 | Goulet, A, Moores, C.A, Cross, R.A. | 登録日 | 2016-10-21 | 公開日 | 2016-11-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | 主引用文献 | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M54
| Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins | 分子名称: | Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Akhmanova, A, Moores, C.A, Baldus, M, Steinmetz, M.O, Topf, M, Roberts, A.J, Grant, B.J, Scarabelli, G, Joseph, A.-J, van Hooff, J.J.E, Houben, K, Hua, S, Luo, Y, Stangier, M.M, Jiang, K, Atherton, J. | 登録日 | 2016-10-20 | 公開日 | 2017-10-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nat. Struct. Mol. Biol., 24, 2017
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8RC1
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4ATX
| Rigor kinesin motor domain with an ordered neck-linker, docked on tubulin dimer, modelled into the 8A cryo-EM map of doublecortin- microtubules decorated with kinesin | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-1 HEAVY CHAIN, ... | 著者 | Liu, J.S, Schubert, C.R, Fu, X, Fourniol, F.J, Jaiswal, J.K, Houdusse, A, Stultz, C.M, Moores, C.A, Walsh, C.A. | 登録日 | 2012-05-10 | 公開日 | 2012-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | 主引用文献 | Molecular Basis for Specific Regulation of Neuronal Kinesin- 3 Motors by Doublecortin Family Proteins. Mol.Cell, 47, 2012
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4ATU
| Human doublecortin N-DC repeat plus linker, and tubulin (2XRP) docked into an 8A cryo-EM map of doublecortin-stabilised microtubules reconstructed in absence of kinesin | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, NEURONAL MIGRATION PROTEIN DOUBLECORTIN, ... | 著者 | Liu, J.S, Schubert, C.R, Fu, X, Fourniol, F.J, Jaiswal, J.K, Houdusse, A, Stultz, C.M, Moores, C.A, Walsh, C.A. | 登録日 | 2012-05-09 | 公開日 | 2012-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | Molecular Basis for Specific Regulation of Neuronal Kinesin- 3 Motors by Doublecortin Family Proteins. Mol.Cell, 47, 2012
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3LRE
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2VE7
| Crystal structure of a bonsai version of the human Ndc80 complex | 分子名称: | GLYCEROL, KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25, ... | 著者 | Ciferri, C, Pasqualato, S, Dos Reis, G, Screpanti, E, Maiolica, A, Polka, J, De Luca, J.G, De Wulf, P, Salek, M, Rappsilber, J, Moores, C.A, Salmon, E.D, Musacchio, A. | 登録日 | 2007-10-17 | 公開日 | 2008-05-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex Cell(Cambridge,Mass.), 133, 2008
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1QAG
| Actin binding region of the dystrophin homologue utrophin | 分子名称: | UTROPHIN ACTIN BINDING REGION | 著者 | Keep, N.H, Winder, S.J, Moores, C.A, Walke, S, Norwood, F.L.M, Kendrick-Jones, J. | 登録日 | 1999-03-05 | 公開日 | 2000-01-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer Structure Fold.Des., 7, 1999
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6TIW
| Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2) | 分子名称: | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... | 著者 | Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | 登録日 | 2019-11-22 | 公開日 | 2020-03-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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6TA4
| Human kinesin-5 motor domain in the AMPPNP state bound to microtubules | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ... | 著者 | Pena, A.P, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | 登録日 | 2019-10-29 | 公開日 | 2020-03-04 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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4ABO
| Mal3 CH domain homology model and mammalian tubulin (2XRP) docked into the 8.6-Angstrom cryo-EM map of Mal3-GTPgammaS-microtubules | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MICROTUBULE INTEGRITY PROTEIN MAL3, ... | 著者 | Maurer, S.P, Fourniol, F.J, Bohner, G, Moores, C.A, Surrey, T. | 登録日 | 2011-12-09 | 公開日 | 2012-06-06 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | 主引用文献 | Ebs Recognize a Nucleotide-Dependent Structural CAP at Growing Microtubule Ends. Cell(Cambridge,Mass.), 149, 2012
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6TA3
| Human kinesin-5 motor domain in the GSK-1 state bound to microtubules (Conformation 1) | 分子名称: | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... | 著者 | Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | 登録日 | 2019-10-29 | 公開日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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7NBA
| Plasmodium falciparum kinesin-5 motor domain bound to AMPPNP, complexed with 14 protofilament microtubule. | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin motor domain-containing protein,Kinesin motor domain-containing protein, MAGNESIUM ION, ... | 著者 | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | 登録日 | 2021-01-25 | 公開日 | 2021-10-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297, 2021
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7NB8
| Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule. | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-5, MAGNESIUM ION, ... | 著者 | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | 登録日 | 2021-01-25 | 公開日 | 2021-10-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297, 2021
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5MM7
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5MM4
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4UXT
| Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ... | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | 登録日 | 2014-08-27 | 公開日 | 2014-09-24 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXS
| Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | 登録日 | 2014-08-27 | 公開日 | 2014-09-24 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXR
| Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | 登録日 | 2014-08-27 | 公開日 | 2014-09-24 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UY0
| Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | 登録日 | 2014-08-27 | 公開日 | 2014-09-24 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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