7NB8
Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule.
Summary for 7NB8
Entry DOI | 10.2210/pdb7nb8/pdb |
EMDB information | 12257 |
Descriptor | Tubulin alpha-1B chain, Tubulin beta chain, Kinesin-5, ... (6 entities in total) |
Functional Keywords | cytoskeleton, motor protein, mitosis |
Biological source | Plasmodium falciparum (isolate 3D7) More |
Total number of polymer chains | 3 |
Total formula weight | 148115.33 |
Authors | Cook, A.D.,Roberts, A.,Atherton, J.,Tewari, R.,Topf, M.,Moores, C.A. (deposition date: 2021-01-25, release date: 2021-10-13, Last modification date: 2024-07-10) |
Primary citation | Cook, A.D.,Roberts, A.J.,Atherton, J.,Tewari, R.,Topf, M.,Moores, C.A. Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297:101063-101063, 2021 Cited by PubMed: 34375637DOI: 10.1016/j.jbc.2021.101063 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.4 Å) |
Structure validation
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