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5M5N

Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations.

Summary for 5M5N
Entry DOI10.2210/pdb5m5n/pdb
EMDB information3445
DescriptorTubulin alpha-1D chain, Tubulin beta-2B chain, Kinesin-like protein cut7, ... (8 entities in total)
Functional Keywordsmicrotubule-bound s.pombe kinesin-5, motor domain, amppnp bound state, modeller 9.10 2013-08 complex, motor protein
Biological sourceSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
More
Cellular locationCytoplasm, cytoskeleton : Q2HJ86 Q6B856
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body: P24339
Total number of polymer chains3
Total formula weight143256.74
Authors
Goulet, A.,Moores, C.A.,Cross, R.A. (deposition date: 2016-10-22, release date: 2016-11-30, Last modification date: 2017-08-02)
Primary citationBritto, M.,Goulet, A.,Rizvi, S.,von Loeffelholz, O.,Moores, C.A.,Cross, R.A.
Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism.
Proc. Natl. Acad. Sci. U.S.A., 113:E7483-E7489, 2016
Cited by
PubMed: 27834216
DOI: 10.1073/pnas.1611581113
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (9.3 Å)
Structure validation

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