2VE7

Crystal structure of a bonsai version of the human Ndc80 complex

Summary for 2VE7

DescriptorKINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25, KINETOCHORE PROTEIN NUF2, KINETOCHORE PROTEIN SPC24, GLYCEROL, ... (5 entities in total)
Functional Keywordsmitosis, centromere, cell cycle, microtubule, kinetochore, cell division, calponin homology
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus Q9HBM1 Q8NBT2
Total number of polymer chains4
Total molecular weight131061.84
Authors
Ciferri, C.,Pasqualato, S.,Dos Reis, G.,Screpanti, E.,Maiolica, A.,Polka, J.,De Luca, J.G.,De Wulf, P.,Salek, M.,Rappsilber, J.,Moores, C.A.,Salmon, E.D.,Musacchio, A. (deposition date: 2007-10-17, release date: 2008-05-13, Last modification date: 2017-06-21)
Primary citation
Ciferri, C.,Pasqualato, S.,Screpanti, E.,Varetti, G.,Santaguida, S.,Dos Reis, G.,Maiolica, A.,Polka, J.,De Luca, J.G.,De Wulf, P.,Salek, M.,Rappsilber, J.,Moores, C.A.,Salmon, E.D.,Musacchio, A.
Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
Cell(Cambridge,Mass.), 133:427-, 2008
PubMed: 18455984 (PDB entries with the same primary citation)
DOI: 10.1016/J.CELL.2008.03.020
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.88 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.242121.9%8.9%10.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report