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2VE7

Crystal structure of a bonsai version of the human Ndc80 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0007059biological_processchromosome segregation
A0031262cellular_componentNdc80 complex
A0051315biological_processattachment of mitotic spindle microtubules to kinetochore
B0007059biological_processchromosome segregation
B0031262cellular_componentNdc80 complex
B0051315biological_processattachment of mitotic spindle microtubules to kinetochore
C0000776cellular_componentkinetochore
C0031262cellular_componentNdc80 complex
D0000776cellular_componentkinetochore
D0031262cellular_componentNdc80 complex
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE IPH C2194
ChainResidue
ATYR228
CCYS134
CTHR137
DARG19

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE IPH D2198
ChainResidue
DTHR137
BTYR228
BPHE243
CARG19
DALA133
DCYS134

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL B2225
ChainResidue
ALYS199
AGLU200
BPRO120
BTHR171
BVAL172
BGLY173

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL A2222
ChainResidue
APRO120
ASER121
AVAL172
AGLY173
BPHE135

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine; by NEK2","evidences":[{"source":"PubMed","id":"12386167","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9D0F1","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues65
DetailsRegion: {"description":"Interaction with the C-terminus of SPBC25"}
ChainResidueDetails

246333

PDB entries from 2025-12-17

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